• Version:
  • 11.0 [archived version]
STRINGSTRING
IMMP2L IMMP2L HNRNPCL1 HNRNPCL1 SLC35F2 SLC35F2 DOPEY2 DOPEY2 CCDC68 CCDC68 CSMD1 CSMD1 ZNF804A ZNF804A WBP1L WBP1L PTPRD PTPRD CACNA1C CACNA1C TENM3 TENM3
"CSMD1" - CUB and sushi domain-containing protein 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CSMD1CUB and sushi domain-containing protein 1; Potential suppressor of squamous cell carcinomas; Protein phosphatase 1 regulatory subunits (3565 aa)    
Predicted Functional Partners:
SLC35F2
Solute carrier family 35 member F2; Putative solute transporter (374 aa)
           
  0.794
DOPEY2
Protein dopey-2; May be involved in protein traffic between late Golgi and early endosomes; Belongs to the dopey family (2298 aa)
     
   
  0.750
WBP1L
WW domain binding protein 1 like; WBP1/VOPP1 family (363 aa)
           
  0.708
IMMP2L
Mitochondrial inner membrane protease subunit 2; Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO; Belongs to the peptidase S26 family. IMP2 subfamily (175 aa)
           
  0.665
CCDC68
Coiled-coil domain-containing protein 68; Centriolar protein required for centriole subdistal appendage assembly and microtubule anchoring in interphase cells. Together with CCDC120, cooperate with subdistal appendage components ODF2, NIN and CEP170 for hierarchical subdistal appendage assembly (335 aa)
           
  0.645
ZNF804A
Zinc finger protein 804A (1209 aa)
     
   
  0.613
HNRNPCL1
Heterogeneous nuclear ribonucleoprotein C-like 1; May play a role in nucleosome assembly by neutralizing basic proteins such as A and B core hnRNPs; RNA binding motif containing (293 aa)
           
  0.597
PTPRD
Receptor-type tyrosine-protein phosphatase delta; Can bidirectionally induce pre- and post-synaptic differentiation of neurons by mediating interaction with IL1RAP and IL1RAPL1 trans-synaptically. Involved in pre-synaptic differentiation through interaction with SLITRK2; Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily (1912 aa)
     
   
  0.592
CACNA1C
Voltage-dependent L-type calcium channel subunit alpha-1C; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1C gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the ’high-voltage activated’ (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by o [...] (2186 aa)
     
   
  0.563
TENM3
Teneurin-3; Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Promotes axon guidance and homophilic cell adhesion. Plays a role in the development of the visual pathway; regulates the formation in ipsilateral retinal mapping to both the dorsal lateral geniculate nucleus (dLGN) and the superior colliculus (SC). May be involved in the differentiation of the fibroblast-like cells in the superficial layer of mandibular condylar cartilage into chondrocytes. May function as a cellular signal transducer (By similarity) (2699 aa)
     
   
  0.559
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (1%) [HD]