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  • 11.0 [archived version]
STRINGSTRING
FOXD4L1 FOXD4L1 RBMXL3 RBMXL3 ARHGEF11 ARHGEF11 LRRIQ4 LRRIQ4 PEAR1 PEAR1 ETV3L ETV3L LRRC71 LRRC71 KIAA1211 KIAA1211 KNCN KNCN ZNHIT1 ZNHIT1 ZNF649 ZNF649
"ETV3L" - ETS translocation variant 3-like protein in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
ETV3LETS translocation variant 3-like protein; Transcriptional regulator; ETS transcription factor family (361 aa)    
Predicted Functional Partners:
LRRC71
Leucine-rich repeat-containing protein 71; Leucine rich repeat containing 71 (559 aa)
            
  0.793
RBMXL3
RNA binding motif protein, X-linked like 3 (1067 aa)
            
  0.705
PEAR1
Platelet endothelial aggregation receptor 1; When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells; Belongs to the MEGF family (1037 aa)
            
  0.660
ZNHIT1
Zinc finger HIT domain-containing protein 1; Seems to play a role in p53-mediated apoptosis induction. Binds to NR1D2 and relieves it of its inhibitory effect on the transcription of APOC3 without affecting its DNA-binding activity; Belongs to the ZNHIT1 family (154 aa)
            
  0.598
KIAA1211
Uncharacterized protein KIAA1211; KIAA1211 (1233 aa)
            
  0.593
LRRIQ4
Leucine rich repeats and IQ motif containing 4 (560 aa)
            
  0.585
ARHGEF11
Rho guanine nucleotide exchange factor 11; May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. Involved in neurotrophin-induced neurite outgrowth; PDZ domain containing (1562 aa)
  
       
  0.581
FOXD4L1
Forkhead box D4 like 1 (408 aa)
        
 
  0.573
ZNF649
Zinc finger protein 649; Transcriptional repressor. Regulator of transcriptional factor complexes and may suppress SRE and AP-1 transcription activities mediated by growth factor signaling pathways; Belongs to the krueppel C2H2-type zinc-finger protein family (505 aa)
        
 
  0.521
KNCN
Kinocilin (101 aa)
            
  0.517
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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