| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACN9 | LYRM1 | ENSP00000414066 | ENSP00000379367 | Succinate dehydrogenase assembly factor 3, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1 | LYR motif-containing protein 1; May promote cell proliferation and inhibition of apoptosis of preadipocytes; Belongs to the complex I LYR family | 0.525 |
| ACN9 | LYRM2 | ENSP00000414066 | ENSP00000430025 | Succinate dehydrogenase assembly factor 3, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1 | LYR motif containing 2 | 0.802 |
| ACN9 | LYRM4 | ENSP00000414066 | ENSP00000420026 | Succinate dehydrogenase assembly factor 3, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1 | LYR motif-containing protein 4; Required for nuclear and mitochondrial iron-sulfur protein biosynthesis; LYR motif containing | 0.784 |
| ACN9 | LYRM5 | ENSP00000414066 | ENSP00000370761 | Succinate dehydrogenase assembly factor 3, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1 | Electron transfer flavoprotein regulatory factor 1; Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme (composed of ETFA and ETFB) | 0.600 |
| ACN9 | LYRM7 | ENSP00000414066 | ENSP00000368688 | Succinate dehydrogenase assembly factor 3, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1 | Complex III assembly factor LYRM7; Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane; LYR motif containing | 0.698 |
| ACN9 | LYRM9 | ENSP00000414066 | ENSP00000368397 | Succinate dehydrogenase assembly factor 3, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1 | LYR motif containing 9; Belongs to the complex I LYR family. LYRM9 subfamily | 0.473 |
| ACN9 | NDUFAB1 | ENSP00000414066 | ENSP00000458770 | Succinate dehydrogenase assembly factor 3, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1 | Acyl carrier protein, mitochondrial; Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity). Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain; Belongs to the acyl carrier protein (ACP) family | 0.878 |
| ACN9 | NFS1 | ENSP00000414066 | ENSP00000363205 | Succinate dehydrogenase assembly factor 3, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1 | Cysteine desulfurase, mitochondrial; Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron- sulfur (Fe-S) clusters. May be involved in the biosynthesis of molybdenum cofactor | 0.590 |
| LYRM1 | ACN9 | ENSP00000379367 | ENSP00000414066 | LYR motif-containing protein 1; May promote cell proliferation and inhibition of apoptosis of preadipocytes; Belongs to the complex I LYR family | Succinate dehydrogenase assembly factor 3, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1 | 0.525 |
| LYRM1 | LYRM2 | ENSP00000379367 | ENSP00000430025 | LYR motif-containing protein 1; May promote cell proliferation and inhibition of apoptosis of preadipocytes; Belongs to the complex I LYR family | LYR motif containing 2 | 0.743 |
| LYRM1 | LYRM4 | ENSP00000379367 | ENSP00000420026 | LYR motif-containing protein 1; May promote cell proliferation and inhibition of apoptosis of preadipocytes; Belongs to the complex I LYR family | LYR motif-containing protein 4; Required for nuclear and mitochondrial iron-sulfur protein biosynthesis; LYR motif containing | 0.531 |
| LYRM1 | LYRM5 | ENSP00000379367 | ENSP00000370761 | LYR motif-containing protein 1; May promote cell proliferation and inhibition of apoptosis of preadipocytes; Belongs to the complex I LYR family | Electron transfer flavoprotein regulatory factor 1; Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme (composed of ETFA and ETFB) | 0.689 |
| LYRM1 | LYRM7 | ENSP00000379367 | ENSP00000368688 | LYR motif-containing protein 1; May promote cell proliferation and inhibition of apoptosis of preadipocytes; Belongs to the complex I LYR family | Complex III assembly factor LYRM7; Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane; LYR motif containing | 0.466 |
| LYRM1 | LYRM9 | ENSP00000379367 | ENSP00000368397 | LYR motif-containing protein 1; May promote cell proliferation and inhibition of apoptosis of preadipocytes; Belongs to the complex I LYR family | LYR motif containing 9; Belongs to the complex I LYR family. LYRM9 subfamily | 0.642 |
| LYRM2 | ACN9 | ENSP00000430025 | ENSP00000414066 | LYR motif containing 2 | Succinate dehydrogenase assembly factor 3, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1 | 0.802 |
| LYRM2 | LYRM1 | ENSP00000430025 | ENSP00000379367 | LYR motif containing 2 | LYR motif-containing protein 1; May promote cell proliferation and inhibition of apoptosis of preadipocytes; Belongs to the complex I LYR family | 0.743 |
| LYRM2 | LYRM4 | ENSP00000430025 | ENSP00000420026 | LYR motif containing 2 | LYR motif-containing protein 4; Required for nuclear and mitochondrial iron-sulfur protein biosynthesis; LYR motif containing | 0.716 |
| LYRM2 | LYRM5 | ENSP00000430025 | ENSP00000370761 | LYR motif containing 2 | Electron transfer flavoprotein regulatory factor 1; Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme (composed of ETFA and ETFB) | 0.803 |
| LYRM2 | LYRM7 | ENSP00000430025 | ENSP00000368688 | LYR motif containing 2 | Complex III assembly factor LYRM7; Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane; LYR motif containing | 0.637 |
| LYRM2 | LYRM9 | ENSP00000430025 | ENSP00000368397 | LYR motif containing 2 | LYR motif containing 9; Belongs to the complex I LYR family. LYRM9 subfamily | 0.701 |
