| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANKRD18A | FAM196A | ENSP00000382610 | ENSP00000429763 | Ankyrin repeat domain-containing protein 18A; Ankyrin repeat domain containing | Protein FAM196A; Family with sequence similarity 196 member A | 0.581 |
| ANKRD18A | TMEM132E | ENSP00000382610 | ENSP00000316532 | Ankyrin repeat domain-containing protein 18A; Ankyrin repeat domain containing | Transmembrane protein 132E; Required for normal inner ear hair cell function and hearing; Belongs to the TMEM132 family | 0.529 |
| ANKRD18A | ZNF541 | ENSP00000382610 | ENSP00000375770 | Ankyrin repeat domain-containing protein 18A; Ankyrin repeat domain containing | Zinc finger protein 541; Component of some chromatin remodeling multiprotein complex that plays a role during spermatogenesis; Myb/SANT domain containing | 0.585 |
| C15orf59 | FAM196A | ENSP00000457205 | ENSP00000429763 | UPF0583 protein C15orf59; Chromosome 15 open reading frame 59 | Protein FAM196A; Family with sequence similarity 196 member A | 0.677 |
| C15orf59 | IQSEC3 | ENSP00000457205 | ENSP00000437554 | UPF0583 protein C15orf59; Chromosome 15 open reading frame 59 | IQ motif and SEC7 domain-containing protein 3; Acts as a guanine nucleotide exchange factor (GEF) for ARF1 | 0.585 |
| CPXM1 | DOCK1 | ENSP00000369979 | ENSP00000280333 | Probable carboxypeptidase X1; May be involved in cell-cell interactions. No carboxypeptidase activity was found yet (By similarity); M14 carboxypeptidases | Dedicator of cytokinesis protein 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 | 0.559 |
| CPXM1 | FAM196A | ENSP00000369979 | ENSP00000429763 | Probable carboxypeptidase X1; May be involved in cell-cell interactions. No carboxypeptidase activity was found yet (By similarity); M14 carboxypeptidases | Protein FAM196A; Family with sequence similarity 196 member A | 0.798 |
| CPXM1 | NKX2-3 | ENSP00000369979 | ENSP00000342828 | Probable carboxypeptidase X1; May be involved in cell-cell interactions. No carboxypeptidase activity was found yet (By similarity); M14 carboxypeptidases | Homeobox protein Nkx-2.3; Transcription factor; NKL subclass homeoboxes and pseudogenes | 0.480 |
| CPXM1 | PPP2R2B | ENSP00000369979 | ENSP00000377936 | Probable carboxypeptidase X1; May be involved in cell-cell interactions. No carboxypeptidase activity was found yet (By similarity); M14 carboxypeptidases | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity (By similarity). Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance (By similarity) | 0.598 |
| CPXM1 | STC1 | ENSP00000369979 | ENSP00000290271 | Probable carboxypeptidase X1; May be involved in cell-cell interactions. No carboxypeptidase activity was found yet (By similarity); M14 carboxypeptidases | Stanniocalcin-1; Stimulates renal phosphate reabsorption, and could therefore prevent hypercalcemia | 0.566 |
| DOCK1 | CPXM1 | ENSP00000280333 | ENSP00000369979 | Dedicator of cytokinesis protein 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 | Probable carboxypeptidase X1; May be involved in cell-cell interactions. No carboxypeptidase activity was found yet (By similarity); M14 carboxypeptidases | 0.559 |
| DOCK1 | FAM196A | ENSP00000280333 | ENSP00000429763 | Dedicator of cytokinesis protein 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 | Protein FAM196A; Family with sequence similarity 196 member A | 0.599 |
| DOCK1 | NKX2-3 | ENSP00000280333 | ENSP00000342828 | Dedicator of cytokinesis protein 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 | Homeobox protein Nkx-2.3; Transcription factor; NKL subclass homeoboxes and pseudogenes | 0.415 |
| DOCK1 | PPP2R2B | ENSP00000280333 | ENSP00000377936 | Dedicator of cytokinesis protein 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity (By similarity). Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance (By similarity) | 0.445 |
| DOCK1 | STC1 | ENSP00000280333 | ENSP00000290271 | Dedicator of cytokinesis protein 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 | Stanniocalcin-1; Stimulates renal phosphate reabsorption, and could therefore prevent hypercalcemia | 0.612 |
| FAM196A | ANKRD18A | ENSP00000429763 | ENSP00000382610 | Protein FAM196A; Family with sequence similarity 196 member A | Ankyrin repeat domain-containing protein 18A; Ankyrin repeat domain containing | 0.581 |
| FAM196A | C15orf59 | ENSP00000429763 | ENSP00000457205 | Protein FAM196A; Family with sequence similarity 196 member A | UPF0583 protein C15orf59; Chromosome 15 open reading frame 59 | 0.677 |
| FAM196A | CPXM1 | ENSP00000429763 | ENSP00000369979 | Protein FAM196A; Family with sequence similarity 196 member A | Probable carboxypeptidase X1; May be involved in cell-cell interactions. No carboxypeptidase activity was found yet (By similarity); M14 carboxypeptidases | 0.798 |
| FAM196A | DOCK1 | ENSP00000429763 | ENSP00000280333 | Protein FAM196A; Family with sequence similarity 196 member A | Dedicator of cytokinesis protein 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 | 0.599 |
| FAM196A | IQSEC3 | ENSP00000429763 | ENSP00000437554 | Protein FAM196A; Family with sequence similarity 196 member A | IQ motif and SEC7 domain-containing protein 3; Acts as a guanine nucleotide exchange factor (GEF) for ARF1 | 0.548 |
