| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GKN1 | NKX6-3 | ENSP00000367172 | ENSP00000429553 | Gastrokine-1; Has mitogenic activity and may be involved in maintaining the integrity of the gastric mucosal epithelium; BRICHOS domain containing | Homeobox protein Nkx-6.3; Putative transcription factor, which may be involved in patterning of central nervous system and pancreas; NKL subclass homeoboxes and pseudogenes | 0.561 |
| KCNIP3 | NKX6-3 | ENSP00000295225 | ENSP00000429553 | Calsenilin; Calcium-dependent transcriptional repressor that binds to the DRE element of genes including PDYN and FOS. Affinity for DNA is reduced upon binding to calcium and enhanced by binding to magnesium. Seems to be involved in nociception (By similarity); EF-hand domain containing | Homeobox protein Nkx-6.3; Putative transcription factor, which may be involved in patterning of central nervous system and pancreas; NKL subclass homeoboxes and pseudogenes | 0.400 |
| NEUROG3 | NKX6-3 | ENSP00000242462 | ENSP00000429553 | Neurogenin-3; Acts as a transcriptional regulator. Together with NKX2- 2, initiates transcriptional activation of NEUROD1. Involved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types (By similarity); Basic helix-loop-helix proteins | Homeobox protein Nkx-6.3; Putative transcription factor, which may be involved in patterning of central nervous system and pancreas; NKL subclass homeoboxes and pseudogenes | 0.411 |
| NKX1-1 | NKX6-3 | ENSP00000407978 | ENSP00000429553 | NK1 transcription factor-related protein 1; NKL subclass homeoboxes and pseudogenes; Belongs to the NK-1 homeobox family | Homeobox protein Nkx-6.3; Putative transcription factor, which may be involved in patterning of central nervous system and pancreas; NKL subclass homeoboxes and pseudogenes | 0.451 |
| NKX2-3 | NKX6-3 | ENSP00000342828 | ENSP00000429553 | Homeobox protein Nkx-2.3; Transcription factor; NKL subclass homeoboxes and pseudogenes | Homeobox protein Nkx-6.3; Putative transcription factor, which may be involved in patterning of central nervous system and pancreas; NKL subclass homeoboxes and pseudogenes | 0.446 |
| NKX6-3 | GKN1 | ENSP00000429553 | ENSP00000367172 | Homeobox protein Nkx-6.3; Putative transcription factor, which may be involved in patterning of central nervous system and pancreas; NKL subclass homeoboxes and pseudogenes | Gastrokine-1; Has mitogenic activity and may be involved in maintaining the integrity of the gastric mucosal epithelium; BRICHOS domain containing | 0.561 |
| NKX6-3 | KCNIP3 | ENSP00000429553 | ENSP00000295225 | Homeobox protein Nkx-6.3; Putative transcription factor, which may be involved in patterning of central nervous system and pancreas; NKL subclass homeoboxes and pseudogenes | Calsenilin; Calcium-dependent transcriptional repressor that binds to the DRE element of genes including PDYN and FOS. Affinity for DNA is reduced upon binding to calcium and enhanced by binding to magnesium. Seems to be involved in nociception (By similarity); EF-hand domain containing | 0.400 |
| NKX6-3 | NEUROG3 | ENSP00000429553 | ENSP00000242462 | Homeobox protein Nkx-6.3; Putative transcription factor, which may be involved in patterning of central nervous system and pancreas; NKL subclass homeoboxes and pseudogenes | Neurogenin-3; Acts as a transcriptional regulator. Together with NKX2- 2, initiates transcriptional activation of NEUROD1. Involved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types (By similarity); Basic helix-loop-helix proteins | 0.411 |
| NKX6-3 | NKX1-1 | ENSP00000429553 | ENSP00000407978 | Homeobox protein Nkx-6.3; Putative transcription factor, which may be involved in patterning of central nervous system and pancreas; NKL subclass homeoboxes and pseudogenes | NK1 transcription factor-related protein 1; NKL subclass homeoboxes and pseudogenes; Belongs to the NK-1 homeobox family | 0.451 |
| NKX6-3 | NKX2-3 | ENSP00000429553 | ENSP00000342828 | Homeobox protein Nkx-6.3; Putative transcription factor, which may be involved in patterning of central nervous system and pancreas; NKL subclass homeoboxes and pseudogenes | Homeobox protein Nkx-2.3; Transcription factor; NKL subclass homeoboxes and pseudogenes | 0.446 |
| NKX6-3 | TGIF2 | ENSP00000429553 | ENSP00000362981 | Homeobox protein Nkx-6.3; Putative transcription factor, which may be involved in patterning of central nervous system and pancreas; NKL subclass homeoboxes and pseudogenes | Homeobox protein TGIF2; Transcriptional repressor, which probably repress transcription by binding directly the 5’-CTGTCAA-3’ DNA sequence or by interacting with TGF-beta activated SMAD proteins. Probably represses transcription via the recruitment of histone deacetylase proteins; TALE class homeoboxes and pseudogenes | 0.429 |
| NKX6-3 | TLE2 | ENSP00000429553 | ENSP00000466542 | Homeobox protein Nkx-6.3; Putative transcription factor, which may be involved in patterning of central nervous system and pancreas; NKL subclass homeoboxes and pseudogenes | Transducin-like enhancer protein 2; Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity); Belongs to the WD repeat Groucho/TLE family | 0.422 |
| NKX6-3 | TMEM88 | ENSP00000429553 | ENSP00000301599 | Homeobox protein Nkx-6.3; Putative transcription factor, which may be involved in patterning of central nervous system and pancreas; NKL subclass homeoboxes and pseudogenes | Transmembrane protein 88; Inhibits the Wnt/beta-catenin signaling pathway. Crucial for heart development and acts downstream of GATA factors in the pre-cardiac mesoderm to specify lineage commitment of cardiomyocyte development | 0.488 |
| TGIF2 | NKX6-3 | ENSP00000362981 | ENSP00000429553 | Homeobox protein TGIF2; Transcriptional repressor, which probably repress transcription by binding directly the 5’-CTGTCAA-3’ DNA sequence or by interacting with TGF-beta activated SMAD proteins. Probably represses transcription via the recruitment of histone deacetylase proteins; TALE class homeoboxes and pseudogenes | Homeobox protein Nkx-6.3; Putative transcription factor, which may be involved in patterning of central nervous system and pancreas; NKL subclass homeoboxes and pseudogenes | 0.429 |
| TLE2 | NKX6-3 | ENSP00000466542 | ENSP00000429553 | Transducin-like enhancer protein 2; Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity); Belongs to the WD repeat Groucho/TLE family | Homeobox protein Nkx-6.3; Putative transcription factor, which may be involved in patterning of central nervous system and pancreas; NKL subclass homeoboxes and pseudogenes | 0.422 |
| TMEM88 | NKX6-3 | ENSP00000301599 | ENSP00000429553 | Transmembrane protein 88; Inhibits the Wnt/beta-catenin signaling pathway. Crucial for heart development and acts downstream of GATA factors in the pre-cardiac mesoderm to specify lineage commitment of cardiomyocyte development | Homeobox protein Nkx-6.3; Putative transcription factor, which may be involved in patterning of central nervous system and pancreas; NKL subclass homeoboxes and pseudogenes | 0.488 |
