| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C10orf128 | FAM92A1 | ENSP00000363268 | ENSP00000429367 | Putative uncharacterized protein C10orf128; Chromosome 10 open reading frame 128 | Protein FAM92A; May play a role in ciliogenesis. In cooperation with CBY1 may facilitate ciliogenesis likely by the recruitment and fusion of endosomal vesicles at distal appendages during early stages of ciliogenesis | 0.541 |
| CBY1 | FAM92A1 | ENSP00000478962 | ENSP00000429367 | Protein chibby homolog 1; Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation; Belongs to the chibby family | Protein FAM92A; May play a role in ciliogenesis. In cooperation with CBY1 may facilitate ciliogenesis likely by the recruitment and fusion of endosomal vesicles at distal appendages during early stages of ciliogenesis | 0.673 |
| CCDC180 | FAM92A1 | ENSP00000434727 | ENSP00000429367 | Coiled-coil domain containing 180 | Protein FAM92A; May play a role in ciliogenesis. In cooperation with CBY1 may facilitate ciliogenesis likely by the recruitment and fusion of endosomal vesicles at distal appendages during early stages of ciliogenesis | 0.629 |
| CCDC180 | FRMD4B | ENSP00000434727 | ENSP00000381549 | Coiled-coil domain containing 180 | FERM domain-containing protein 4B; Member of GRP1 signaling complexes that are acutely recruited to plasma membrane ruffles in response to insulin receptor signaling. May function as a scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex. Plays a redundant role with FRMD4A in epithelial polarization; FERM domain containing | 0.470 |
| CCDC180 | OGFRL1 | ENSP00000434727 | ENSP00000359464 | Coiled-coil domain containing 180 | Opioid growth factor receptor like 1 | 0.556 |
| CCDC180 | ZNF345 | ENSP00000434727 | ENSP00000431202 | Coiled-coil domain containing 180 | Zinc finger protein 345; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.473 |
| FAM92A1 | C10orf128 | ENSP00000429367 | ENSP00000363268 | Protein FAM92A; May play a role in ciliogenesis. In cooperation with CBY1 may facilitate ciliogenesis likely by the recruitment and fusion of endosomal vesicles at distal appendages during early stages of ciliogenesis | Putative uncharacterized protein C10orf128; Chromosome 10 open reading frame 128 | 0.541 |
| FAM92A1 | CBY1 | ENSP00000429367 | ENSP00000478962 | Protein FAM92A; May play a role in ciliogenesis. In cooperation with CBY1 may facilitate ciliogenesis likely by the recruitment and fusion of endosomal vesicles at distal appendages during early stages of ciliogenesis | Protein chibby homolog 1; Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation; Belongs to the chibby family | 0.673 |
| FAM92A1 | CCDC180 | ENSP00000429367 | ENSP00000434727 | Protein FAM92A; May play a role in ciliogenesis. In cooperation with CBY1 may facilitate ciliogenesis likely by the recruitment and fusion of endosomal vesicles at distal appendages during early stages of ciliogenesis | Coiled-coil domain containing 180 | 0.629 |
| FAM92A1 | FRMD4B | ENSP00000429367 | ENSP00000381549 | Protein FAM92A; May play a role in ciliogenesis. In cooperation with CBY1 may facilitate ciliogenesis likely by the recruitment and fusion of endosomal vesicles at distal appendages during early stages of ciliogenesis | FERM domain-containing protein 4B; Member of GRP1 signaling complexes that are acutely recruited to plasma membrane ruffles in response to insulin receptor signaling. May function as a scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex. Plays a redundant role with FRMD4A in epithelial polarization; FERM domain containing | 0.517 |
| FAM92A1 | LYRM1 | ENSP00000429367 | ENSP00000379367 | Protein FAM92A; May play a role in ciliogenesis. In cooperation with CBY1 may facilitate ciliogenesis likely by the recruitment and fusion of endosomal vesicles at distal appendages during early stages of ciliogenesis | LYR motif-containing protein 1; May promote cell proliferation and inhibition of apoptosis of preadipocytes; Belongs to the complex I LYR family | 0.490 |
| FAM92A1 | LZTS1 | ENSP00000429367 | ENSP00000370981 | Protein FAM92A; May play a role in ciliogenesis. In cooperation with CBY1 may facilitate ciliogenesis likely by the recruitment and fusion of endosomal vesicles at distal appendages during early stages of ciliogenesis | Leucine zipper putative tumor suppressor 1; Involved in the regulation of cell growth. May stabilize the active CDC2-cyclin B1 complex and thereby contribute to the regulation of the cell cycle and the prevention of uncontrolled cell proliferation. May act as a tumor suppressor; Leucine zipper tumor suppressor family | 0.546 |
| FAM92A1 | OGFRL1 | ENSP00000429367 | ENSP00000359464 | Protein FAM92A; May play a role in ciliogenesis. In cooperation with CBY1 may facilitate ciliogenesis likely by the recruitment and fusion of endosomal vesicles at distal appendages during early stages of ciliogenesis | Opioid growth factor receptor like 1 | 0.621 |
| FAM92A1 | TTBK2 | ENSP00000429367 | ENSP00000267890 | Protein FAM92A; May play a role in ciliogenesis. In cooperation with CBY1 may facilitate ciliogenesis likely by the recruitment and fusion of endosomal vesicles at distal appendages during early stages of ciliogenesis | Tau-tubulin kinase 2; Serine/threonine kinase that acts as a key regulator of ciliogenesis- controls the initiation of ciliogenesis by binding to the distal end of the basal body and promoting the removal of CCP110, which caps the mother centriole, leading to the recruitment of IFT proteins, which build the ciliary axoneme. Has some substrate preference for proteins that are already phosphorylated on a Tyr residue at the +2 position relative to the phosphorylation site. Able to phosphorylate tau on serines in vitro | 0.503 |
| FAM92A1 | VWA8 | ENSP00000429367 | ENSP00000368612 | Protein FAM92A; May play a role in ciliogenesis. In cooperation with CBY1 may facilitate ciliogenesis likely by the recruitment and fusion of endosomal vesicles at distal appendages during early stages of ciliogenesis | Von Willebrand factor A domain-containing protein 8; Exhibits ATPase activity in vitro | 0.586 |
| FAM92A1 | ZNF345 | ENSP00000429367 | ENSP00000431202 | Protein FAM92A; May play a role in ciliogenesis. In cooperation with CBY1 may facilitate ciliogenesis likely by the recruitment and fusion of endosomal vesicles at distal appendages during early stages of ciliogenesis | Zinc finger protein 345; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.549 |
| FRMD4B | CCDC180 | ENSP00000381549 | ENSP00000434727 | FERM domain-containing protein 4B; Member of GRP1 signaling complexes that are acutely recruited to plasma membrane ruffles in response to insulin receptor signaling. May function as a scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex. Plays a redundant role with FRMD4A in epithelial polarization; FERM domain containing | Coiled-coil domain containing 180 | 0.470 |
| FRMD4B | FAM92A1 | ENSP00000381549 | ENSP00000429367 | FERM domain-containing protein 4B; Member of GRP1 signaling complexes that are acutely recruited to plasma membrane ruffles in response to insulin receptor signaling. May function as a scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex. Plays a redundant role with FRMD4A in epithelial polarization; FERM domain containing | Protein FAM92A; May play a role in ciliogenesis. In cooperation with CBY1 may facilitate ciliogenesis likely by the recruitment and fusion of endosomal vesicles at distal appendages during early stages of ciliogenesis | 0.517 |
| FRMD4B | OGFRL1 | ENSP00000381549 | ENSP00000359464 | FERM domain-containing protein 4B; Member of GRP1 signaling complexes that are acutely recruited to plasma membrane ruffles in response to insulin receptor signaling. May function as a scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex. Plays a redundant role with FRMD4A in epithelial polarization; FERM domain containing | Opioid growth factor receptor like 1 | 0.476 |
| FRMD4B | ZNF345 | ENSP00000381549 | ENSP00000431202 | FERM domain-containing protein 4B; Member of GRP1 signaling complexes that are acutely recruited to plasma membrane ruffles in response to insulin receptor signaling. May function as a scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex. Plays a redundant role with FRMD4A in epithelial polarization; FERM domain containing | Zinc finger protein 345; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.442 |
