| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C1orf109 | ZNF674 | ENSP00000350704 | ENSP00000429148 | Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition | Zinc finger protein 674; May be involved in transcriptional regulation; X-linked mental retardation | 0.514 |
| CHST7 | SLC9A7 | ENSP00000276055 | ENSP00000480916 | Carbohydrate sulfotransferase 7; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues. Preferentially acts on mannose-linked GlcNAc. Also able to catalyze the transfer of sulfate to position 6 of the N- acetylgalactosamine (GalNAc) residue of chondroitin. Also acts on core 2 mucin-type oligosaccharide and N-acetyllactosamine oligomer with a lower efficiency. Has weak or no activity toward keratan sulfate and oligosaccharides containing the Galbeta1- [...] | Sodium/hydrogen exchanger 7; Mediates electroneutral exchange of protons for Na(+) and K(+) across endomembranes. May contribute to Golgi volume and cation homeostasis; Solute carriers | 0.771 |
| CHST7 | ZNF674 | ENSP00000276055 | ENSP00000429148 | Carbohydrate sulfotransferase 7; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues. Preferentially acts on mannose-linked GlcNAc. Also able to catalyze the transfer of sulfate to position 6 of the N- acetylgalactosamine (GalNAc) residue of chondroitin. Also acts on core 2 mucin-type oligosaccharide and N-acetyllactosamine oligomer with a lower efficiency. Has weak or no activity toward keratan sulfate and oligosaccharides containing the Galbeta1- [...] | Zinc finger protein 674; May be involved in transcriptional regulation; X-linked mental retardation | 0.748 |
| CLHC1 | ZNF674 | ENSP00000384869 | ENSP00000429148 | Clathrin heavy chain linker domain containing 1 | Zinc finger protein 674; May be involved in transcriptional regulation; X-linked mental retardation | 0.532 |
| DLG3 | TRIM28 | ENSP00000363480 | ENSP00000253024 | Disks large homolog 3; Required for learning most likely through its role in synaptic plasticity following NMDA receptor signaling; Membrane associated guanylate kinases | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.406 |
| DLG3 | ZNF674 | ENSP00000363480 | ENSP00000429148 | Disks large homolog 3; Required for learning most likely through its role in synaptic plasticity following NMDA receptor signaling; Membrane associated guanylate kinases | Zinc finger protein 674; May be involved in transcriptional regulation; X-linked mental retardation | 0.518 |
| FCHO1 | ZNF674 | ENSP00000473001 | ENSP00000429148 | F-BAR domain only protein 1; Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. May regulate Bmp signaling by regulating clathrin-mediated endocytosis of Bmp receptors; F-BAR domain containing | Zinc finger protein 674; May be involved in transcriptional regulation; X-linked mental retardation | 0.546 |
| NBPF10 | ZNF674 | ENSP00000463957 | ENSP00000429148 | Neuroblastoma breakpoint family member 10; NBPF member 10 | Zinc finger protein 674; May be involved in transcriptional regulation; X-linked mental retardation | 0.567 |
| NXF5 | ZNF674 | ENSP00000426978 | ENSP00000429148 | Nuclear RNA export factor 5; Could be involved in the export of mRNA from the nucleus to the cytoplasm. Could also have a role in polarized cytoplasmic transport and localization of mRNA in neurons | Zinc finger protein 674; May be involved in transcriptional regulation; X-linked mental retardation | 0.522 |
| SLC9A7 | CHST7 | ENSP00000480916 | ENSP00000276055 | Sodium/hydrogen exchanger 7; Mediates electroneutral exchange of protons for Na(+) and K(+) across endomembranes. May contribute to Golgi volume and cation homeostasis; Solute carriers | Carbohydrate sulfotransferase 7; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues. Preferentially acts on mannose-linked GlcNAc. Also able to catalyze the transfer of sulfate to position 6 of the N- acetylgalactosamine (GalNAc) residue of chondroitin. Also acts on core 2 mucin-type oligosaccharide and N-acetyllactosamine oligomer with a lower efficiency. Has weak or no activity toward keratan sulfate and oligosaccharides containing the Galbeta1- [...] | 0.771 |
| SLC9A7 | ZNF674 | ENSP00000480916 | ENSP00000429148 | Sodium/hydrogen exchanger 7; Mediates electroneutral exchange of protons for Na(+) and K(+) across endomembranes. May contribute to Golgi volume and cation homeostasis; Solute carriers | Zinc finger protein 674; May be involved in transcriptional regulation; X-linked mental retardation | 0.647 |
| TRIM28 | DLG3 | ENSP00000253024 | ENSP00000363480 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Disks large homolog 3; Required for learning most likely through its role in synaptic plasticity following NMDA receptor signaling; Membrane associated guanylate kinases | 0.406 |
| TRIM28 | ZNF674 | ENSP00000253024 | ENSP00000429148 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 674; May be involved in transcriptional regulation; X-linked mental retardation | 0.545 |
| ZNF385B | ZNF674 | ENSP00000386845 | ENSP00000429148 | Zinc finger protein 385B; May play a role in p53/TP53-mediated apoptosis | Zinc finger protein 674; May be involved in transcriptional regulation; X-linked mental retardation | 0.806 |
| ZNF674 | C1orf109 | ENSP00000429148 | ENSP00000350704 | Zinc finger protein 674; May be involved in transcriptional regulation; X-linked mental retardation | Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition | 0.514 |
| ZNF674 | CHST7 | ENSP00000429148 | ENSP00000276055 | Zinc finger protein 674; May be involved in transcriptional regulation; X-linked mental retardation | Carbohydrate sulfotransferase 7; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues. Preferentially acts on mannose-linked GlcNAc. Also able to catalyze the transfer of sulfate to position 6 of the N- acetylgalactosamine (GalNAc) residue of chondroitin. Also acts on core 2 mucin-type oligosaccharide and N-acetyllactosamine oligomer with a lower efficiency. Has weak or no activity toward keratan sulfate and oligosaccharides containing the Galbeta1- [...] | 0.748 |
| ZNF674 | CLHC1 | ENSP00000429148 | ENSP00000384869 | Zinc finger protein 674; May be involved in transcriptional regulation; X-linked mental retardation | Clathrin heavy chain linker domain containing 1 | 0.532 |
| ZNF674 | DLG3 | ENSP00000429148 | ENSP00000363480 | Zinc finger protein 674; May be involved in transcriptional regulation; X-linked mental retardation | Disks large homolog 3; Required for learning most likely through its role in synaptic plasticity following NMDA receptor signaling; Membrane associated guanylate kinases | 0.518 |
| ZNF674 | FCHO1 | ENSP00000429148 | ENSP00000473001 | Zinc finger protein 674; May be involved in transcriptional regulation; X-linked mental retardation | F-BAR domain only protein 1; Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. May regulate Bmp signaling by regulating clathrin-mediated endocytosis of Bmp receptors; F-BAR domain containing | 0.546 |
| ZNF674 | NBPF10 | ENSP00000429148 | ENSP00000463957 | Zinc finger protein 674; May be involved in transcriptional regulation; X-linked mental retardation | Neuroblastoma breakpoint family member 10; NBPF member 10 | 0.567 |
