ZNF829 protein (human) - STRING database

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ZNF829

Zinc finger protein 829; May be involved in transcriptional regulation; Zinc fingers C2H2-type (513 aa)

Predicted Functional Partners:

TRIM28

0.551

PBX2

0.479

POU2F2

0.449

CCDC82

0.439

ATF7

0.420

AIM1

0.403

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIM1	ZNF829	ENSP00000358062	ENSP00000428679	Beta/gamma crystallin domain-containing protein 1; May function as suppressor of malignant melanoma. It may exert its effects through interactions with the cytoskeleton	Zinc finger protein 829; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.403
ATF7	ZNF829	ENSP00000399465	ENSP00000428679	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus- 5’-GTGACGT[AG][AG]- 3’), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family; Basic leucine zipper proteins	Zinc finger protein 829; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.420
CCDC82	POU2F2	ENSP00000278520	ENSP00000431603	Coiled-coil domain containing 82	POU domain, class 2, transcription factor 2; Transcription factor that specifically binds to the octamer motif (5’-ATTTGCAT-3’). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter; POU class homeoboxes and pseudogenes	0.403
CCDC82	ZNF829	ENSP00000278520	ENSP00000428679	Coiled-coil domain containing 82	Zinc finger protein 829; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.439
PBX2	ZNF829	ENSP00000364190	ENSP00000428679	Pre-B-cell leukemia transcription factor 2; Transcriptional activator that binds the sequence 5’- ATCAATCAA-3’. Activates transcription of PF4 in complex with MEIS1; TALE class homeoboxes and pseudogenes	Zinc finger protein 829; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.479
POU2F2	CCDC82	ENSP00000431603	ENSP00000278520	POU domain, class 2, transcription factor 2; Transcription factor that specifically binds to the octamer motif (5’-ATTTGCAT-3’). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter; POU class homeoboxes and pseudogenes	Coiled-coil domain containing 82	0.403
POU2F2	ZNF829	ENSP00000431603	ENSP00000428679	POU domain, class 2, transcription factor 2; Transcription factor that specifically binds to the octamer motif (5’-ATTTGCAT-3’). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter; POU class homeoboxes and pseudogenes	Zinc finger protein 829; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.449
TRIM28	ZNF829	ENSP00000253024	ENSP00000428679	Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...]	Zinc finger protein 829; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.551
ZNF829	AIM1	ENSP00000428679	ENSP00000358062	Zinc finger protein 829; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Beta/gamma crystallin domain-containing protein 1; May function as suppressor of malignant melanoma. It may exert its effects through interactions with the cytoskeleton	0.403
ZNF829	ATF7	ENSP00000428679	ENSP00000399465	Zinc finger protein 829; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus- 5’-GTGACGT[AG][AG]- 3’), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family; Basic leucine zipper proteins	0.420
ZNF829	CCDC82	ENSP00000428679	ENSP00000278520	Zinc finger protein 829; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Coiled-coil domain containing 82	0.439
ZNF829	PBX2	ENSP00000428679	ENSP00000364190	Zinc finger protein 829; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Pre-B-cell leukemia transcription factor 2; Transcriptional activator that binds the sequence 5’- ATCAATCAA-3’. Activates transcription of PF4 in complex with MEIS1; TALE class homeoboxes and pseudogenes	0.479
ZNF829	POU2F2	ENSP00000428679	ENSP00000431603	Zinc finger protein 829; May be involved in transcriptional regulation; Zinc fingers C2H2-type	POU domain, class 2, transcription factor 2; Transcription factor that specifically binds to the octamer motif (5’-ATTTGCAT-3’). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter; POU class homeoboxes and pseudogenes	0.449
ZNF829	TRIM28	ENSP00000428679	ENSP00000253024	Zinc finger protein 829; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...]	0.551

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