ANKAR protein (human) - STRING database

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ANKAR

Ankyrin and armadillo repeat containing (1434 aa)

Predicted Functional Partners:

OSGEPL1

0.904

TMF1

0.802

TMEM194B

0.657

ORMDL1

0.656

DIRC1

0.634

AK9

0.578

STARD9

0.561

C2orf88

0.558

ASNSD1

0.555

WDR75

0.552

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AK9	ANKAR	ENSP00000410186	ENSP00000427882	Adenylate kinase 9; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has both nucleoside monophosphate and diphosphate kinase activities. Catalyzes the phosphorylation of AMP, dAMP, CMP and dCMP with ATP as phosphate donor and of CMP with GTP as phosphate donor. Also catalyzes the production of ATP, CTP, GTP, UTP, dATP, dCTP, dGTP and TTP from the corresponding diphosphate substrates with either ATP or GTP as phosphate donor. Shows substrate preference of CDP > UDP > ADP > GDP > TDP; Belongs to the adenylate kin [...]	Ankyrin and armadillo repeat containing	0.578
AK9	STARD9	ENSP00000410186	ENSP00000290607	Adenylate kinase 9; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has both nucleoside monophosphate and diphosphate kinase activities. Catalyzes the phosphorylation of AMP, dAMP, CMP and dCMP with ATP as phosphate donor and of CMP with GTP as phosphate donor. Also catalyzes the production of ATP, CTP, GTP, UTP, dATP, dCTP, dGTP and TTP from the corresponding diphosphate substrates with either ATP or GTP as phosphate donor. Shows substrate preference of CDP > UDP > ADP > GDP > TDP; Belongs to the adenylate kin [...]	StAR-related lipid transfer protein 9; Microtubule-dependent motor protein required for spindle pole assembly during mitosis. Required to stabilize the pericentriolar material (PCM); Kinesins	0.472
ANKAR	AK9	ENSP00000427882	ENSP00000410186	Ankyrin and armadillo repeat containing	Adenylate kinase 9; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has both nucleoside monophosphate and diphosphate kinase activities. Catalyzes the phosphorylation of AMP, dAMP, CMP and dCMP with ATP as phosphate donor and of CMP with GTP as phosphate donor. Also catalyzes the production of ATP, CTP, GTP, UTP, dATP, dCTP, dGTP and TTP from the corresponding diphosphate substrates with either ATP or GTP as phosphate donor. Shows substrate preference of CDP > UDP > ADP > GDP > TDP; Belongs to the adenylate kin [...]	0.578
ANKAR	ASNSD1	ENSP00000427882	ENSP00000260952	Ankyrin and armadillo repeat containing	Asparagine synthetase domain containing 1	0.555
ANKAR	C2orf88	ENSP00000427882	ENSP00000345107	Ankyrin and armadillo repeat containing	Small membrane A-kinase anchor protein; Binds to type I regulatory subunits of protein kinase A (PKA-RI) and may anchor/target them to the plasma membrane; Belongs to the small membrane AKAP family	0.558
ANKAR	DIRC1	ENSP00000427882	ENSP00000307860	Ankyrin and armadillo repeat containing	Disrupted in renal carcinoma 1	0.634
ANKAR	ORMDL1	ENSP00000427882	ENSP00000326869	Ankyrin and armadillo repeat containing	ORM1-like protein 1; Negative regulator of sphingolipid synthesis	0.656
ANKAR	OSGEPL1	ENSP00000427882	ENSP00000264151	Ankyrin and armadillo repeat containing	Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance	0.904
ANKAR	STARD9	ENSP00000427882	ENSP00000290607	Ankyrin and armadillo repeat containing	StAR-related lipid transfer protein 9; Microtubule-dependent motor protein required for spindle pole assembly during mitosis. Required to stabilize the pericentriolar material (PCM); Kinesins	0.561
ANKAR	TMEM194B	ENSP00000427882	ENSP00000386292	Ankyrin and armadillo repeat containing	Nuclear envelope integral membrane protein 2; Transmembrane protein 194B; Belongs to the NEMP family	0.657
ANKAR	TMF1	ENSP00000427882	ENSP00000381567	Ankyrin and armadillo repeat containing	TATA element modulatory factor; Potential coactivator of the androgen receptor. Mediates STAT3 degradation. May play critical roles in two RAB6-dependent retrograde transport processes- one from endosomes to the Golgi and the other from the Golgi to the ER. This protein binds the HIV-1 TATA element and inhibits transcriptional activation by the TATA-binding protein (TBP)	0.802
ANKAR	WDR75	ENSP00000427882	ENSP00000314193	Ankyrin and armadillo repeat containing	WD repeat-containing protein 75; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre- ribosomal RNA transcription by RNA polymerase I; UTPa subcomplex	0.552
ASNSD1	ANKAR	ENSP00000260952	ENSP00000427882	Asparagine synthetase domain containing 1	Ankyrin and armadillo repeat containing	0.555
ASNSD1	C2orf88	ENSP00000260952	ENSP00000345107	Asparagine synthetase domain containing 1	Small membrane A-kinase anchor protein; Binds to type I regulatory subunits of protein kinase A (PKA-RI) and may anchor/target them to the plasma membrane; Belongs to the small membrane AKAP family	0.558
ASNSD1	DIRC1	ENSP00000260952	ENSP00000307860	Asparagine synthetase domain containing 1	Disrupted in renal carcinoma 1	0.491
ASNSD1	ORMDL1	ENSP00000260952	ENSP00000326869	Asparagine synthetase domain containing 1	ORM1-like protein 1; Negative regulator of sphingolipid synthesis	0.676
ASNSD1	OSGEPL1	ENSP00000260952	ENSP00000264151	Asparagine synthetase domain containing 1	Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance	0.562
ASNSD1	TMEM194B	ENSP00000260952	ENSP00000386292	Asparagine synthetase domain containing 1	Nuclear envelope integral membrane protein 2; Transmembrane protein 194B; Belongs to the NEMP family	0.668
ASNSD1	WDR75	ENSP00000260952	ENSP00000314193	Asparagine synthetase domain containing 1	WD repeat-containing protein 75; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre- ribosomal RNA transcription by RNA polymerase I; UTPa subcomplex	0.494
C2orf88	ANKAR	ENSP00000345107	ENSP00000427882	Small membrane A-kinase anchor protein; Binds to type I regulatory subunits of protein kinase A (PKA-RI) and may anchor/target them to the plasma membrane; Belongs to the small membrane AKAP family	Ankyrin and armadillo repeat containing	0.558

page 1 of 4

Network

Fusion

Experiments

Cooccurrence

Textmining

Coexpression

Databases

Neighborhood

© STRING Consortium 2020

Credits

Access

Info

About