• Version:
  • 11.0 [archived version]
STRINGSTRING
PLA2G4B PLA2G4B TMEM192 TMEM192 TRIM60 TRIM60 FAM218A FAM218A NINJ1 NINJ1 TMEM254 TMEM254 ENSG00000168970 ENSG00000168970
"FAM218A" - Protein FAM218A in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM218AProtein FAM218A; Family with sequence similarity 218 member A (157 aa)    
Predicted Functional Partners:
TMEM192
Transmembrane protein 192 (271 aa)
           
  0.642
TRIM60
Tripartite motif containing 60; Belongs to the TRIM/RBCC family (471 aa)
           
  0.588
ENSG00000168970
JMJD7-PLA2G4B readthrough (1012 aa)
           
  0.516
PLA2G4B
Cytosolic phospholipase A2 beta; Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position with a preference for arachidonoyl phospholipids. Has a much weaker activity than PLA2G4A. Isoform 3 has calcium-dependent activity against palmitoyl-arachidonyl-phosphatidylethanolamine and low level lysophospholipase activity but no activity against phosphatidylcholine. Isoform 5 does have activity against phosphatidylcholine; C2 domain containing phospholipases (781 aa)
           
  0.511
NINJ1
Ninjurin-1; Homophilic cell adhesion molecule that promotes axonal growth. May play a role in nerve regeneration and in the formation and function of other tissues. Cell adhesion requires divalent cations (152 aa)
           
  0.429
TMEM254
Transmembrane protein 254 (123 aa)
           
  0.426
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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