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STRINGSTRING
FGF10 FGF10 CT45A1 CT45A1 C11orf57 C11orf57 PRPF40A PRPF40A RP9 RP9 SREK1 SREK1 SREK1IP1 SREK1IP1 CWC27 CWC27 PPWD1 PPWD1 LYAR LYAR FAM159B FAM159B
"SREK1IP1" - Protein SREK1IP1 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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SREK1IP1Protein SREK1IP1; Possible splicing regulator involved in the control of cellular survival (155 aa)    
Predicted Functional Partners:
FGF10
Fibroblast growth factor 10; Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. May play a role in wound healing; Belongs to the heparin-binding growth factors family (208 aa)
      
      0.805
PRPF40A
Pre-mRNA-processing factor 40 homolog A; Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing; Spliceosomal A complex (930 aa)
        
      0.803
LYAR
Cell growth-regulating nucleolar protein; Zinc fingers C2HC-type (379 aa)
        
      0.803
RP9
Retinitis pigmentosa 9 protein; Is thought to be a target protein for the PIM1 kinase. May play some roles in B-cell proliferation in association with PIM1 (By similarity) (221 aa)
      
      0.785
PPWD1
Peptidylprolyl isomerase domain and WD repeat-containing protein 1; Putative peptidylprolyl isomerase (PPIase). PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved in pre-mRNA splicing; Cyclophilin peptidylprolyl isomerases (646 aa)
      
   
  0.742
CT45A1
Cancer/testis antigen family 45 member A1; Belongs to the CT45 family (189 aa)
        
      0.737
C11orf57
Uncharacterized protein NKAPD1; Chromosome 11 open reading frame 57 (293 aa)
        
      0.716
CWC27
Peptidyl-prolyl cis-trans isomerase CWC27 homolog; PPIases accelerate the folding of proteins; Belongs to the cyclophilin-type PPIase family (472 aa)
      
 
  0.699
FAM159B
Membrane protein FAM159B; Family with sequence similarity 159, member B (160 aa)
            
  0.694
SREK1
Splicing regulatory glutamine/lysine-rich protein 1; Participates in the regulation of alternative splicing by modulating the activity of other splice facors. Inhibits the splicing activity of SFRS1, SFRS2 and SFRS6. Augments the splicing activity of SFRS3 (By similarity); RNA binding motif containing (624 aa)
      
   
  0.681
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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