| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACRBP | AKAP3 | ENSP00000229243 | ENSP00000228850 | Acrosin-binding protein; May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin; Armadillo-like helical domain containing | A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction; A-kinase anchoring proteins | 0.420 |
| ACRBP | ROPN1 | ENSP00000229243 | ENSP00000184183 | Acrosin-binding protein; May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin; Armadillo-like helical domain containing | Ropporin-1A; Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation; Belongs to the ropporin family | 0.565 |
| ACRBP | ROPN1B | ENSP00000229243 | ENSP00000426271 | Acrosin-binding protein; May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin; Armadillo-like helical domain containing | Ropporin-1B; Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation; Belongs to the ropporin family | 0.449 |
| ACRBP | SUCLA2 | ENSP00000229243 | ENSP00000367923 | Acrosin-binding protein; May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin; Armadillo-like helical domain containing | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit (By similarity) | 0.577 |
| AKAP3 | ACRBP | ENSP00000228850 | ENSP00000229243 | A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction; A-kinase anchoring proteins | Acrosin-binding protein; May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin; Armadillo-like helical domain containing | 0.420 |
| AKAP3 | AKAP4 | ENSP00000228850 | ENSP00000351327 | A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction; A-kinase anchoring proteins | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility; A-kinase anchoring proteins | 0.453 |
| AKAP3 | PRKAR2A | ENSP00000228850 | ENSP00000265563 | A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction; A-kinase anchoring proteins | cAMP-dependent protein kinase type II-alpha regulatory subunit; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase | 0.569 |
| AKAP3 | ROPN1 | ENSP00000228850 | ENSP00000184183 | A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction; A-kinase anchoring proteins | Ropporin-1A; Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation; Belongs to the ropporin family | 0.943 |
| AKAP3 | ROPN1B | ENSP00000228850 | ENSP00000426271 | A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction; A-kinase anchoring proteins | Ropporin-1B; Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation; Belongs to the ropporin family | 0.447 |
| AKAP4 | AKAP3 | ENSP00000351327 | ENSP00000228850 | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility; A-kinase anchoring proteins | A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction; A-kinase anchoring proteins | 0.453 |
| AKAP4 | PRKAR2A | ENSP00000351327 | ENSP00000265563 | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility; A-kinase anchoring proteins | cAMP-dependent protein kinase type II-alpha regulatory subunit; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase | 0.955 |
| AKAP4 | ROPN1 | ENSP00000351327 | ENSP00000184183 | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility; A-kinase anchoring proteins | Ropporin-1A; Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation; Belongs to the ropporin family | 0.697 |
| AKAP4 | ROPN1B | ENSP00000351327 | ENSP00000426271 | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility; A-kinase anchoring proteins | Ropporin-1B; Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation; Belongs to the ropporin family | 0.502 |
| GOLT1B | ROPN1B | ENSP00000229314 | ENSP00000426271 | Vesicle transport protein GOT1B; May be involved in fusion of ER-derived transport vesicles with the Golgi complex | Ropporin-1B; Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation; Belongs to the ropporin family | 0.441 |
| GOLT1B | TULP4 | ENSP00000229314 | ENSP00000356064 | Vesicle transport protein GOT1B; May be involved in fusion of ER-derived transport vesicles with the Golgi complex | Tubby-related protein 4; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the TUB family | 0.457 |
| LRCOL1 | NYAP1 | ENSP00000479730 | ENSP00000300179 | Leucine-rich colipase-like protein 1; Leucine rich colipase like 1 | Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1; Activates PI3K and concomitantly recruits the WAVE1 complex to the close vicinity of PI3K and regulates neuronal morphogenesis; Belongs to the NYAP family | 0.700 |
| LRCOL1 | ROPN1 | ENSP00000479730 | ENSP00000184183 | Leucine-rich colipase-like protein 1; Leucine rich colipase like 1 | Ropporin-1A; Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation; Belongs to the ropporin family | 0.537 |
| LRCOL1 | ROPN1B | ENSP00000479730 | ENSP00000426271 | Leucine-rich colipase-like protein 1; Leucine rich colipase like 1 | Ropporin-1B; Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation; Belongs to the ropporin family | 0.537 |
| NYAP1 | LRCOL1 | ENSP00000300179 | ENSP00000479730 | Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1; Activates PI3K and concomitantly recruits the WAVE1 complex to the close vicinity of PI3K and regulates neuronal morphogenesis; Belongs to the NYAP family | Leucine-rich colipase-like protein 1; Leucine rich colipase like 1 | 0.700 |
| NYAP1 | ROPN1 | ENSP00000300179 | ENSP00000184183 | Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1; Activates PI3K and concomitantly recruits the WAVE1 complex to the close vicinity of PI3K and regulates neuronal morphogenesis; Belongs to the NYAP family | Ropporin-1A; Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation; Belongs to the ropporin family | 0.446 |
