• Version:
  • 11.0 [archived version]
STRINGSTRING
GLB1L3 GLB1L3 FAM71C FAM71C PAIP1 PAIP1 C5orf28 C5orf28 KNCN KNCN SETD9 SETD9 FASTKD3 FASTKD3 ETV3L ETV3L KIAA1211 KIAA1211 ZNHIT1 ZNHIT1 ICE1 ICE1
"C5orf28" - Transmembrane protein 267 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C5orf28Transmembrane protein 267; Chromosome 5 open reading frame 28 (215 aa)    
Predicted Functional Partners:
SETD9
SET domain containing 9 (299 aa)
           
  0.763
PAIP1
Polyadenylate-binding protein-interacting protein 1; Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of [...] (479 aa)
     
   
  0.631
KNCN
Kinocilin (101 aa)
           
  0.578
FAM71C
Protein FAM71C; Family with sequence similarity 71 member C (241 aa)
           
  0.556
GLB1L3
Beta-galactosidase-1-like protein 3; Galactosidase beta 1 like 3 (653 aa)
           
  0.510
ZNHIT1
Zinc finger HIT domain-containing protein 1; Seems to play a role in p53-mediated apoptosis induction. Binds to NR1D2 and relieves it of its inhibitory effect on the transcription of APOC3 without affecting its DNA-binding activity; Belongs to the ZNHIT1 family (154 aa)
           
  0.500
ETV3L
ETS translocation variant 3-like protein; Transcriptional regulator; ETS transcription factor family (361 aa)
           
  0.497
KIAA1211
Uncharacterized protein KIAA1211; KIAA1211 (1233 aa)
           
  0.476
ICE1
Little elongation complex subunit 1; Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. Specifically acts as a scaffold protein that promotes the LEC complex formation and recruitment and RNA polymerase II occupancy at snRNA genes in subnuclear bodies; Belongs to the ICE1 family (2266 aa)
     
   
  0.465
FASTKD3
FAST kinase domain-containing protein 3, mitochondrial; Required for normal mitochondrial respiration; Belongs to the FAST kinase family (662 aa)
     
   
  0.462
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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