• Version:
  • 11.0 [archived version]
STRINGSTRING
GPR125 GPR125 RAB5B RAB5B SGSH SGSH SEL1L3 SEL1L3 SERPINB7 SERPINB7 CCDC149 CCDC149 ACAP2 ACAP2 AADACL3 AADACL3 SLC35B4 SLC35B4 OTUD5 OTUD5 KCNJ4 KCNJ4
"CCDC149" - Coiled-coil domain containing 149 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
CCDC149Coiled-coil domain containing 149 (529 aa)    
Predicted Functional Partners:
AADACL3
Arylacetamide deacetylase-like 3; Arylacetamide deacetylase family (350 aa)
           
  0.679
SEL1L3
Protein sel-1 homolog 3; SEL1L family member 3 (1132 aa)
           
  0.556
SGSH
N-sulphoglucosamine sulphohydrolase; Catalyzes a step in lysosomal heparan sulfate degradation; Belongs to the sulfatase family (502 aa)
           
  0.533
ACAP2
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2; GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6); Ankyrin repeat domain containing (778 aa)
           
  0.530
SLC35B4
UDP-xylose and UDP-N-acetylglucosamine transporter; Sugar transporter that specifically mediates the transport of UDP-xylose (UDP-Xyl) and UDP-N-acetylglucosamine (UDP-GlcNAc) from cytosol into Golgi; Belongs to the nucleotide-sugar transporter family. SLC35B subfamily (331 aa)
           
  0.526
SERPINB7
Serpin B7; Might function as an inhibitor of Lys-specific proteases. Might influence the maturation of megakaryocytes via its action as a serpin; Serpin peptidase inhibitors (380 aa)
           
  0.514
GPR125
Adhesion G protein-coupled receptor A3; Orphan receptor that may have a role in planar cell polarity pathway; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily (1321 aa)
           
  0.448
OTUD5
OTU domain-containing protein 5; Deubiquitinating enzyme that functions as negative regulator of the innate immune system. Acts via TRAF3 deubiquitination and subsequent suppression of type I interferon (IFN) production. Has peptidase activity towards ’Lys-48’- and ’Lys-63’-linked polyubiquitin chains. Can also cleave ’Lys-11’- linked ubiquitin chains (in vitro) (571 aa)
           
  0.444
KCNJ4
Inward rectifier potassium channel 4; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity); Potassium voltage-gated channel subfamily J (445 aa)
           
  0.441
RAB5B
Ras-related protein Rab-5B; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family (215 aa)
           
  0.420
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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