node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AADACL3 | CCDC149 | ENSP00000352268 | ENSP00000425715 | Arylacetamide deacetylase-like 3; Arylacetamide deacetylase family | Coiled-coil domain containing 149 | 0.679 |
AADACL3 | SERPINB7 | ENSP00000352268 | ENSP00000381101 | Arylacetamide deacetylase-like 3; Arylacetamide deacetylase family | Serpin B7; Might function as an inhibitor of Lys-specific proteases. Might influence the maturation of megakaryocytes via its action as a serpin; Serpin peptidase inhibitors | 0.420 |
AADACL3 | SLC35B4 | ENSP00000352268 | ENSP00000367770 | Arylacetamide deacetylase-like 3; Arylacetamide deacetylase family | UDP-xylose and UDP-N-acetylglucosamine transporter; Sugar transporter that specifically mediates the transport of UDP-xylose (UDP-Xyl) and UDP-N-acetylglucosamine (UDP-GlcNAc) from cytosol into Golgi; Belongs to the nucleotide-sugar transporter family. SLC35B subfamily | 0.420 |
ACAP2 | CCDC149 | ENSP00000324287 | ENSP00000425715 | Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2; GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6); Ankyrin repeat domain containing | Coiled-coil domain containing 149 | 0.530 |
CCDC149 | AADACL3 | ENSP00000425715 | ENSP00000352268 | Coiled-coil domain containing 149 | Arylacetamide deacetylase-like 3; Arylacetamide deacetylase family | 0.679 |
CCDC149 | ACAP2 | ENSP00000425715 | ENSP00000324287 | Coiled-coil domain containing 149 | Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2; GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6); Ankyrin repeat domain containing | 0.530 |
CCDC149 | GPR125 | ENSP00000425715 | ENSP00000334952 | Coiled-coil domain containing 149 | Adhesion G protein-coupled receptor A3; Orphan receptor that may have a role in planar cell polarity pathway; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily | 0.448 |
CCDC149 | KCNJ4 | ENSP00000425715 | ENSP00000306497 | Coiled-coil domain containing 149 | Inward rectifier potassium channel 4; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity); Potassium voltage-gated channel subfamily J | 0.441 |
CCDC149 | OTUD5 | ENSP00000425715 | ENSP00000156084 | Coiled-coil domain containing 149 | OTU domain-containing protein 5; Deubiquitinating enzyme that functions as negative regulator of the innate immune system. Acts via TRAF3 deubiquitination and subsequent suppression of type I interferon (IFN) production. Has peptidase activity towards ’Lys-48’- and ’Lys-63’-linked polyubiquitin chains. Can also cleave ’Lys-11’- linked ubiquitin chains (in vitro) | 0.444 |
CCDC149 | RAB5B | ENSP00000425715 | ENSP00000353444 | Coiled-coil domain containing 149 | Ras-related protein Rab-5B; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family | 0.420 |
CCDC149 | SEL1L3 | ENSP00000425715 | ENSP00000382767 | Coiled-coil domain containing 149 | Protein sel-1 homolog 3; SEL1L family member 3 | 0.556 |
CCDC149 | SERPINB7 | ENSP00000425715 | ENSP00000381101 | Coiled-coil domain containing 149 | Serpin B7; Might function as an inhibitor of Lys-specific proteases. Might influence the maturation of megakaryocytes via its action as a serpin; Serpin peptidase inhibitors | 0.514 |
CCDC149 | SGSH | ENSP00000425715 | ENSP00000314606 | Coiled-coil domain containing 149 | N-sulphoglucosamine sulphohydrolase; Catalyzes a step in lysosomal heparan sulfate degradation; Belongs to the sulfatase family | 0.533 |
CCDC149 | SLC35B4 | ENSP00000425715 | ENSP00000367770 | Coiled-coil domain containing 149 | UDP-xylose and UDP-N-acetylglucosamine transporter; Sugar transporter that specifically mediates the transport of UDP-xylose (UDP-Xyl) and UDP-N-acetylglucosamine (UDP-GlcNAc) from cytosol into Golgi; Belongs to the nucleotide-sugar transporter family. SLC35B subfamily | 0.526 |
GPR125 | CCDC149 | ENSP00000334952 | ENSP00000425715 | Adhesion G protein-coupled receptor A3; Orphan receptor that may have a role in planar cell polarity pathway; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily | Coiled-coil domain containing 149 | 0.448 |
KCNJ4 | CCDC149 | ENSP00000306497 | ENSP00000425715 | Inward rectifier potassium channel 4; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity); Potassium voltage-gated channel subfamily J | Coiled-coil domain containing 149 | 0.441 |
OTUD5 | CCDC149 | ENSP00000156084 | ENSP00000425715 | OTU domain-containing protein 5; Deubiquitinating enzyme that functions as negative regulator of the innate immune system. Acts via TRAF3 deubiquitination and subsequent suppression of type I interferon (IFN) production. Has peptidase activity towards ’Lys-48’- and ’Lys-63’-linked polyubiquitin chains. Can also cleave ’Lys-11’- linked ubiquitin chains (in vitro) | Coiled-coil domain containing 149 | 0.444 |
RAB5B | CCDC149 | ENSP00000353444 | ENSP00000425715 | Ras-related protein Rab-5B; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family | Coiled-coil domain containing 149 | 0.420 |
SEL1L3 | CCDC149 | ENSP00000382767 | ENSP00000425715 | Protein sel-1 homolog 3; SEL1L family member 3 | Coiled-coil domain containing 149 | 0.556 |
SERPINB7 | AADACL3 | ENSP00000381101 | ENSP00000352268 | Serpin B7; Might function as an inhibitor of Lys-specific proteases. Might influence the maturation of megakaryocytes via its action as a serpin; Serpin peptidase inhibitors | Arylacetamide deacetylase-like 3; Arylacetamide deacetylase family | 0.420 |