node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADAD1 | ANKRD50 | ENSP00000296513 | ENSP00000425658 | Adenosine deaminase domain-containing protein 1; Plays a role in spermatogenesis. Binds to RNA but not to DNA (By similarity); Adenosine deaminases acting on RNA | Ankyrin repeat domain-containing protein 50; Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1; Ankyrin repeat domain containing | 0.645 |
ADAD1 | ARL9 | ENSP00000296513 | ENSP00000353210 | Adenosine deaminase domain-containing protein 1; Plays a role in spermatogenesis. Binds to RNA but not to DNA (By similarity); Adenosine deaminases acting on RNA | ADP-ribosylation factor-like protein 9; ADP ribosylation factor like GTPase 9; ARF GTPase family | 0.662 |
ADAD1 | LIMCH1 | ENSP00000296513 | ENSP00000316891 | Adenosine deaminase domain-containing protein 1; Plays a role in spermatogenesis. Binds to RNA but not to DNA (By similarity); Adenosine deaminases acting on RNA | LIM and calponin homology domains 1 | 0.514 |
ADAD1 | SPATA5 | ENSP00000296513 | ENSP00000274008 | Adenosine deaminase domain-containing protein 1; Plays a role in spermatogenesis. Binds to RNA but not to DNA (By similarity); Adenosine deaminases acting on RNA | Spermatogenesis-associated protein 5; May be involved in morphological and functional mitochondrial transformations during spermatogenesis; Belongs to the AAA ATPase family. AFG2 subfamily | 0.486 |
ADAD1 | TAPT1 | ENSP00000296513 | ENSP00000385347 | Adenosine deaminase domain-containing protein 1; Plays a role in spermatogenesis. Binds to RNA but not to DNA (By similarity); Adenosine deaminases acting on RNA | Transmembrane anterior posterior transformation protein 1 homolog; Plays a role in primary cilia formation. May act as a downstream effector of HOXC8 possibly by transducing or transmitting extracellular information required for axial skeletal patterning during development (By similarity). May be involved in cartilage and bone development (By similarity). May play a role in the differentiation of cranial neural crest cells (By similarity) | 0.545 |
ADAD1 | TMEM33 | ENSP00000296513 | ENSP00000422473 | Adenosine deaminase domain-containing protein 1; Plays a role in spermatogenesis. Binds to RNA but not to DNA (By similarity); Adenosine deaminases acting on RNA | Transmembrane protein 33; Acts as a regulator of the tubular endoplasmic reticulum (ER) network. Suppresses the RTN3/4-induced formation of the ER tubules. Positively regulates PERK-mediated and IRE1-mediated unfolded protein response signaling | 0.660 |
ANKRD50 | ADAD1 | ENSP00000425658 | ENSP00000296513 | Ankyrin repeat domain-containing protein 50; Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1; Ankyrin repeat domain containing | Adenosine deaminase domain-containing protein 1; Plays a role in spermatogenesis. Binds to RNA but not to DNA (By similarity); Adenosine deaminases acting on RNA | 0.645 |
ANKRD50 | ARL9 | ENSP00000425658 | ENSP00000353210 | Ankyrin repeat domain-containing protein 50; Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1; Ankyrin repeat domain containing | ADP-ribosylation factor-like protein 9; ADP ribosylation factor like GTPase 9; ARF GTPase family | 0.735 |
ANKRD50 | DNAJC13 | ENSP00000425658 | ENSP00000260818 | Ankyrin repeat domain-containing protein 50; Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1; Ankyrin repeat domain containing | DnaJ homolog subfamily C member 13; Involved in membrane trafficking through early endosomes, such as the early endosome to recycling endosome transport implicated in the recycling of transferrin and the early endosome to late endosome transport implicated in degradation of EGF and EGFR. Involved in the regulation of endosomal membrane tubulation and regulates th dynamics of SNX1 on the endosomal membrane; via association with WASHC2 may link the WASH complex to the retromer SNX-BAR subcomplex; Armadillo-like helical domain containing | 0.618 |
ANKRD50 | LIMCH1 | ENSP00000425658 | ENSP00000316891 | Ankyrin repeat domain-containing protein 50; Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1; Ankyrin repeat domain containing | LIM and calponin homology domains 1 | 0.648 |
ANKRD50 | SDCCAG3 | ENSP00000425658 | ENSP00000349929 | Ankyrin repeat domain-containing protein 50; Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1; Ankyrin repeat domain containing | Serologically defined colon cancer antigen 3; May be involved in modulation of TNF response. May be involved in presentation of TNFRSF1A on the cell surface (By similarity). Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1. Involved in the regulation of cytokinesis; the function may involve PTPN13 and GIT1 | 0.777 |
ANKRD50 | SPATA5 | ENSP00000425658 | ENSP00000274008 | Ankyrin repeat domain-containing protein 50; Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1; Ankyrin repeat domain containing | Spermatogenesis-associated protein 5; May be involved in morphological and functional mitochondrial transformations during spermatogenesis; Belongs to the AAA ATPase family. AFG2 subfamily | 0.680 |
ANKRD50 | TAPT1 | ENSP00000425658 | ENSP00000385347 | Ankyrin repeat domain-containing protein 50; Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1; Ankyrin repeat domain containing | Transmembrane anterior posterior transformation protein 1 homolog; Plays a role in primary cilia formation. May act as a downstream effector of HOXC8 possibly by transducing or transmitting extracellular information required for axial skeletal patterning during development (By similarity). May be involved in cartilage and bone development (By similarity). May play a role in the differentiation of cranial neural crest cells (By similarity) | 0.628 |
ANKRD50 | TBC1D5 | ENSP00000425658 | ENSP00000402935 | Ankyrin repeat domain-containing protein 50; Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1; Ankyrin repeat domain containing | TBC1 domain family member 5; May act as a GTPase-activating protein (GAP) for Rab family protein(s). May act as a GAP for RAB7A. Can displace RAB7A and retromer CSC subcomplex from the endosomal membrane to the cytosol; at least retromer displacement seems to require its catalytic activity. Required for retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN); the function seems to require its catalytic activity. Involved in regulation of autophagy. May act as a molecular switch between endosomal and autophagosomal transport and is involved in reprogrammin [...] | 0.625 |
ANKRD50 | TMEM33 | ENSP00000425658 | ENSP00000422473 | Ankyrin repeat domain-containing protein 50; Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1; Ankyrin repeat domain containing | Transmembrane protein 33; Acts as a regulator of the tubular endoplasmic reticulum (ER) network. Suppresses the RTN3/4-induced formation of the ER tubules. Positively regulates PERK-mediated and IRE1-mediated unfolded protein response signaling | 0.739 |
ANKRD50 | VPS26B | ENSP00000425658 | ENSP00000281187 | Ankyrin repeat domain-containing protein 50; Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1; Ankyrin repeat domain containing | Vacuolar protein sorting-associated protein 26B; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for carg [...] | 0.674 |
ARL9 | ADAD1 | ENSP00000353210 | ENSP00000296513 | ADP-ribosylation factor-like protein 9; ADP ribosylation factor like GTPase 9; ARF GTPase family | Adenosine deaminase domain-containing protein 1; Plays a role in spermatogenesis. Binds to RNA but not to DNA (By similarity); Adenosine deaminases acting on RNA | 0.662 |
ARL9 | ANKRD50 | ENSP00000353210 | ENSP00000425658 | ADP-ribosylation factor-like protein 9; ADP ribosylation factor like GTPase 9; ARF GTPase family | Ankyrin repeat domain-containing protein 50; Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1; Ankyrin repeat domain containing | 0.735 |
ARL9 | LIMCH1 | ENSP00000353210 | ENSP00000316891 | ADP-ribosylation factor-like protein 9; ADP ribosylation factor like GTPase 9; ARF GTPase family | LIM and calponin homology domains 1 | 0.599 |
ARL9 | SPATA5 | ENSP00000353210 | ENSP00000274008 | ADP-ribosylation factor-like protein 9; ADP ribosylation factor like GTPase 9; ARF GTPase family | Spermatogenesis-associated protein 5; May be involved in morphological and functional mitochondrial transformations during spermatogenesis; Belongs to the AAA ATPase family. AFG2 subfamily | 0.590 |