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  • 11.0 [archived version]
STRINGSTRING
C12orf56 C12orf56 ARSK ARSK PC PC PRELID2 PRELID2 DTWD2 DTWD2 OCRL OCRL DTWD1 DTWD1 NUDT13 NUDT13 SERINC1 SERINC1 VAPA VAPA ZNF460 ZNF460
"DTWD2" - DTW domain containing 2 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DTWD2DTW domain containing 2 (298 aa)    
Predicted Functional Partners:
NUDT13
Nucleoside diphosphate-linked moiety X motif 13; Nudix hydrolase family (352 aa)
            
  0.707
SERINC1
Serine incorporator 1; Enhances the incorporation of serine into phosphatidylserine and sphingolipids; Belongs to the TDE1 family (453 aa)
            
  0.694
OCRL
Inositol polyphosphate 5-phosphatase OCRL-1; Converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate. Also converts inositol 1,4,5- trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5- tetrakisphosphate to inositol 1,3,4-trisphosphate. May function in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with lysosomes. Involved in primary cilia assembly; Belongs to the inositol 1,4,5-trisphosphate 5- phosphatase type II family (901 aa)
            
  0.657
ARSK
Arylsulfatase family member K; Sulfatases (536 aa)
            
  0.641
PC
Pyruvate carboxylase, mitochondrial; Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate (1178 aa)
        
      0.638
C12orf56
Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56 (622 aa)
            
  0.631
ZNF460
Zinc finger protein 460; May be involved in transcriptional regulation; Zinc fingers C2H2-type (562 aa)
            
  0.562
VAPA
Vesicle-associated membrane protein-associated protein A; VAMP associated protein A (294 aa)
            
  0.534
PRELID2
PRELI domain containing 2 (189 aa)
            
  0.486
DTWD1
DTW domain containing 1; Belongs to the DTW family (304 aa)
            
  0.486
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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