SRP19 protein (human) - STRING database

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Score

SRP19

Signal recognition particle 19 kDa protein; Signal-recognition-particle assembly, binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP (144 aa)

Predicted Functional Partners:

SRP9

0.999

SRP54

0.999

SRP14

0.999

SRP68

0.999

SRP72

0.999

RPL23A

0.998

RPS16

0.998

RPL23

0.997

RPS8

0.996

RPS15

0.996

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RPL23	RPL23A	ENSP00000420311	ENSP00000389103	Ribosomal protein L23	60S ribosomal protein L23a; This protein binds to a specific region on the 26S rRNA; Belongs to the universal ribosomal protein uL23 family	0.999
RPL23	RPS15	ENSP00000420311	ENSP00000467466	Ribosomal protein L23	Ribosomal protein S15	0.999
RPL23	RPS16	ENSP00000420311	ENSP00000251453	Ribosomal protein L23	Ribosomal protein S16	0.999
RPL23	RPS8	ENSP00000420311	ENSP00000379888	Ribosomal protein L23	Ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family	0.999
RPL23	SRP14	ENSP00000420311	ENSP00000267884	Ribosomal protein L23	Signal recognition particle 14 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding	0.996
RPL23	SRP19	ENSP00000420311	ENSP00000424870	Ribosomal protein L23	Signal recognition particle 19 kDa protein; Signal-recognition-particle assembly, binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP	0.997
RPL23	SRP54	ENSP00000420311	ENSP00000451818	Ribosomal protein L23	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein)	0.998
RPL23	SRP68	ENSP00000420311	ENSP00000312066	Ribosomal protein L23	Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function	0.986
RPL23	SRP72	ENSP00000420311	ENSP00000342181	Ribosomal protein L23	Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. Binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function; Belongs to the SRP72 family	0.976
RPL23	SRP9	ENSP00000420311	ENSP00000305230	Ribosomal protein L23	Signal recognition particle 9 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding	0.996
RPL23A	RPL23	ENSP00000389103	ENSP00000420311	60S ribosomal protein L23a; This protein binds to a specific region on the 26S rRNA; Belongs to the universal ribosomal protein uL23 family	Ribosomal protein L23	0.999
RPL23A	RPS15	ENSP00000389103	ENSP00000467466	60S ribosomal protein L23a; This protein binds to a specific region on the 26S rRNA; Belongs to the universal ribosomal protein uL23 family	Ribosomal protein S15	0.999
RPL23A	RPS16	ENSP00000389103	ENSP00000251453	60S ribosomal protein L23a; This protein binds to a specific region on the 26S rRNA; Belongs to the universal ribosomal protein uL23 family	Ribosomal protein S16	0.999
RPL23A	RPS8	ENSP00000389103	ENSP00000379888	60S ribosomal protein L23a; This protein binds to a specific region on the 26S rRNA; Belongs to the universal ribosomal protein uL23 family	Ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family	0.999
RPL23A	SRP14	ENSP00000389103	ENSP00000267884	60S ribosomal protein L23a; This protein binds to a specific region on the 26S rRNA; Belongs to the universal ribosomal protein uL23 family	Signal recognition particle 14 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding	0.997
RPL23A	SRP19	ENSP00000389103	ENSP00000424870	60S ribosomal protein L23a; This protein binds to a specific region on the 26S rRNA; Belongs to the universal ribosomal protein uL23 family	Signal recognition particle 19 kDa protein; Signal-recognition-particle assembly, binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP	0.998
RPL23A	SRP54	ENSP00000389103	ENSP00000451818	60S ribosomal protein L23a; This protein binds to a specific region on the 26S rRNA; Belongs to the universal ribosomal protein uL23 family	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein)	0.999
RPL23A	SRP68	ENSP00000389103	ENSP00000312066	60S ribosomal protein L23a; This protein binds to a specific region on the 26S rRNA; Belongs to the universal ribosomal protein uL23 family	Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function	0.989
RPL23A	SRP72	ENSP00000389103	ENSP00000342181	60S ribosomal protein L23a; This protein binds to a specific region on the 26S rRNA; Belongs to the universal ribosomal protein uL23 family	Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. Binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function; Belongs to the SRP72 family	0.962
RPL23A	SRP9	ENSP00000389103	ENSP00000305230	60S ribosomal protein L23a; This protein binds to a specific region on the 26S rRNA; Belongs to the universal ribosomal protein uL23 family	Signal recognition particle 9 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding	0.997

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