• Version:
  • 11.0 [archived version]
STRINGSTRING
FBRSL1 FBRSL1 OR4N5 OR4N5 MTX3 MTX3 MTX2 MTX2 TOMM70A TOMM70A SAMM50 SAMM50 TIMM50 TIMM50 TOMM22 TOMM22 TOMM40 TOMM40 TOMM40L TOMM40L MRPL43 MRPL43
"MTX3" - Metaxin-3 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTX3Metaxin-3; Could function in transport of proteins into the mitochondrion; Belongs to the metaxin family (251 aa)    
Predicted Functional Partners:
MTX2
Metaxin-2; Involved in transport of proteins into the mitochondrion (263 aa)
     
 
0.744
SAMM50
Sorting and assembly machinery component 50 homolog; Plays a crucial role in the maintenance of the structure of mitochondrial cristae and the proper assembly of the mitochondrial respiratory chain complexes. Required for the assembly of TOMM40 into the TOM complex (469 aa)
     
 
  0.715
TOMM22
Mitochondrial import receptor subunit TOM22 homolog; Central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with the peripheral receptor TOM20 functions as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore; Belongs to the Tom22 family (142 aa)
     
 
  0.705
TOMM40
Mitochondrial import receptor subunit TOM40 homolog; Channel-forming protein essential for import of protein precursors into mitochondria; Belongs to the Tom40 family (361 aa)
     
 
  0.606
TOMM40L
Mitochondrial import receptor subunit TOM40B; Potential channel-forming protein implicated in import of protein precursors into mitochondria; Belongs to the Tom40 family (308 aa)
     
 
  0.606
TOMM70A
Mitochondrial import receptor subunit TOM70; Receptor that accelerates the import of all mitochondrial precursor proteins (608 aa)
       
 
  0.543
OR4N5
Olfactory receptor 4N5; Odorant receptor; Olfactory receptors, family 4 (308 aa)
           
  0.511
MRPL43
Mitochondrial ribosomal protein L43 (235 aa)
     
        0.487
FBRSL1
Fibrosin-1-like protein; Fibrosin like 1; Belongs to the AUTS2 family (1045 aa)
           
  0.486
TIMM50
Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo. Isoform 2 may participate in the release of snRNPs and SMN from the Cajal body; Belongs to the TIM50 family (456 aa)
     
 
  0.485
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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