RFPL4B protein (human) - STRING database

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

RFPL4B

Ret finger protein like 4B; Ring finger proteins (263 aa)

Predicted Functional Partners:

RFPL4A

0.717

DUX4L7

0.648

DUX4L8

0.648

DUX4

0.645

DUX4L1

0.645

ZSCAN4

0.593

KHDC1L

0.584

GOLGA6B

0.548

ARID4B

0.545

TRIM48

0.506

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARID4B	RFPL4B	ENSP00000264183	ENSP00000423391	AT-rich interactive domain-containing protein 4B; Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the Sin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes; AT-rich interaction domain containing	Ret finger protein like 4B; Ring finger proteins	0.545
DUX4	DUX4L1	ENSP00000458065	ENSP00000451207	Double homeobox protein 4; Involved in transcriptional regulation. May regulate microRNA (miRNA) expression; Belongs to the paired homeobox family	Double homeobox 4 like 1; PRD class homeoboxes and pseudogenes	0.800
DUX4	DUX4L7	ENSP00000458065	ENSP00000451411	Double homeobox protein 4; Involved in transcriptional regulation. May regulate microRNA (miRNA) expression; Belongs to the paired homeobox family	Double homeobox 4 like 7; PRD class homeoboxes and pseudogenes	0.801
DUX4	DUX4L8	ENSP00000458065	ENSP00000485452	Double homeobox protein 4; Involved in transcriptional regulation. May regulate microRNA (miRNA) expression; Belongs to the paired homeobox family	Double homeodomain protein DUX4-s; PRD class homeoboxes and pseudogenes	0.801
DUX4	KHDC1L	ENSP00000458065	ENSP00000359415	Double homeobox protein 4; Involved in transcriptional regulation. May regulate microRNA (miRNA) expression; Belongs to the paired homeobox family	Putative KHDC1-like protein; KH domain containing 1 like; Belongs to the KHDC1 family	0.511
DUX4	RFPL4B	ENSP00000458065	ENSP00000423391	Double homeobox protein 4; Involved in transcriptional regulation. May regulate microRNA (miRNA) expression; Belongs to the paired homeobox family	Ret finger protein like 4B; Ring finger proteins	0.645
DUX4	TRIM48	ENSP00000458065	ENSP00000402414	Double homeobox protein 4; Involved in transcriptional regulation. May regulate microRNA (miRNA) expression; Belongs to the paired homeobox family	Tripartite motif containing 48; Belongs to the TRIM/RBCC family	0.457
DUX4	ZSCAN4	ENSP00000458065	ENSP00000321963	Double homeobox protein 4; Involved in transcriptional regulation. May regulate microRNA (miRNA) expression; Belongs to the paired homeobox family	Zinc finger and SCAN domain-containing protein 4; Embryonic stem (ES) cell-specific transcription factor required to regulate ES cell pluripotency. Binds telomeres and plays a key role in genomic stability in ES cells by regulating telomere elongation. Acts as an activator of spontaneous telomere sister chromatid exchange (T-SCE) and telomere elongation in undifferentiated ES cells (By similarity); SCAN domain containing	0.797
DUX4L1	DUX4	ENSP00000451207	ENSP00000458065	Double homeobox 4 like 1; PRD class homeoboxes and pseudogenes	Double homeobox protein 4; Involved in transcriptional regulation. May regulate microRNA (miRNA) expression; Belongs to the paired homeobox family	0.800
DUX4L1	DUX4L7	ENSP00000451207	ENSP00000451411	Double homeobox 4 like 1; PRD class homeoboxes and pseudogenes	Double homeobox 4 like 7; PRD class homeoboxes and pseudogenes	0.808
DUX4L1	DUX4L8	ENSP00000451207	ENSP00000485452	Double homeobox 4 like 1; PRD class homeoboxes and pseudogenes	Double homeodomain protein DUX4-s; PRD class homeoboxes and pseudogenes	0.815
DUX4L1	KHDC1L	ENSP00000451207	ENSP00000359415	Double homeobox 4 like 1; PRD class homeoboxes and pseudogenes	Putative KHDC1-like protein; KH domain containing 1 like; Belongs to the KHDC1 family	0.514
DUX4L1	RFPL4B	ENSP00000451207	ENSP00000423391	Double homeobox 4 like 1; PRD class homeoboxes and pseudogenes	Ret finger protein like 4B; Ring finger proteins	0.645
DUX4L1	TRIM48	ENSP00000451207	ENSP00000402414	Double homeobox 4 like 1; PRD class homeoboxes and pseudogenes	Tripartite motif containing 48; Belongs to the TRIM/RBCC family	0.460
DUX4L1	ZSCAN4	ENSP00000451207	ENSP00000321963	Double homeobox 4 like 1; PRD class homeoboxes and pseudogenes	Zinc finger and SCAN domain-containing protein 4; Embryonic stem (ES) cell-specific transcription factor required to regulate ES cell pluripotency. Binds telomeres and plays a key role in genomic stability in ES cells by regulating telomere elongation. Acts as an activator of spontaneous telomere sister chromatid exchange (T-SCE) and telomere elongation in undifferentiated ES cells (By similarity); SCAN domain containing	0.788
DUX4L7	DUX4	ENSP00000451411	ENSP00000458065	Double homeobox 4 like 7; PRD class homeoboxes and pseudogenes	Double homeobox protein 4; Involved in transcriptional regulation. May regulate microRNA (miRNA) expression; Belongs to the paired homeobox family	0.801
DUX4L7	DUX4L1	ENSP00000451411	ENSP00000451207	Double homeobox 4 like 7; PRD class homeoboxes and pseudogenes	Double homeobox 4 like 1; PRD class homeoboxes and pseudogenes	0.808
DUX4L7	DUX4L8	ENSP00000451411	ENSP00000485452	Double homeobox 4 like 7; PRD class homeoboxes and pseudogenes	Double homeodomain protein DUX4-s; PRD class homeoboxes and pseudogenes	0.814
DUX4L7	KHDC1L	ENSP00000451411	ENSP00000359415	Double homeobox 4 like 7; PRD class homeoboxes and pseudogenes	Putative KHDC1-like protein; KH domain containing 1 like; Belongs to the KHDC1 family	0.526
DUX4L7	RFPL4B	ENSP00000451411	ENSP00000423391	Double homeobox 4 like 7; PRD class homeoboxes and pseudogenes	Ret finger protein like 4B; Ring finger proteins	0.648

page 1 of 4

Network

Cooccurrence

Experiments

Coexpression

Textmining

Neighborhood

Databases

Fusion

© STRING Consortium 2020

Credits

Access

Info

About