• Version:
  • 11.0 [archived version]
STRINGSTRING
CLPS CLPS TMEM99 TMEM99 MT2A MT2A C22orf24 C22orf24 ARHGEF35 ARHGEF35 CXorf40A CXorf40A ZNF630 ZNF630 ARL17A ARL17A SPACA5 SPACA5 TMEM185A TMEM185A CYTH4 CYTH4
"CXorf40A" - Protein CXorf40A in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CXorf40AProtein CXorf40A; May have an important role of cell protection in inflammation reaction (158 aa)    
Predicted Functional Partners:
MT2A
Metallothionein-2; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family (61 aa)
       
 
  0.685
C22orf24
Uncharacterized protein C22orf24; Chromosome 22 open reading frame 24 (160 aa)
           
  0.668
CYTH4
Cytohesin-4; Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF factors through replacement of GDP with GTP; Pleckstrin homology domain containing (394 aa)
           
  0.582
ZNF630
Zinc finger protein 630; May be involved in transcriptional regulation; Zinc fingers C2H2-type (657 aa)
           
  0.575
ARHGEF35
Rho guanine nucleotide exchange factor 35 (484 aa)
           
  0.555
SPACA5
Sperm acrosome associated 5; Belongs to the glycosyl hydrolase 22 family (159 aa)
           
  0.516
CLPS
Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase (112 aa)
           
  0.492
TMEM99
Transmembrane protein 99 (258 aa)
           
  0.473
ARL17A
ADP ribosylation factor like GTPase 17A; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity); ARF GTPase family (177 aa)
           
  0.447
TMEM185A
Transmembrane protein 185A; Belongs to the TMEM185 family (350 aa)
           
  0.440
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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