TRIM34 protein (human) - STRING database

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TRIM34

Tripartite motif containing 34; May function as antiviral protein and may contribute to the defense against retroviral infections; Belongs to the TRIM/RBCC family (488 aa)

Predicted Functional Partners:

ENSG00000258588

0.800

TRAT1

0.719

FLG2

0.671

BBOX1

0.580

OR52H1

0.498

BTBD1

0.470

BTBD2

0.470

OR52B6

0.437

TMLHE

0.434

TRIM5

0.431

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BBOX1	ENSG00000258588	ENSP00000263182	ENSP00000346916	Gamma-butyrobetaine dioxygenase; Catalyzes the formation of L-carnitine from gamma- butyrobetaine; Belongs to the gamma-BBH/TMLD family	Tripartite motif-containing protein 34; May function as antiviral protein and may contribute to the defense against retroviral infections; Belongs to the TRIM/RBCC family	0.587
BBOX1	TRAT1	ENSP00000263182	ENSP00000295756	Gamma-butyrobetaine dioxygenase; Catalyzes the formation of L-carnitine from gamma- butyrobetaine; Belongs to the gamma-BBH/TMLD family	T-cell receptor-associated transmembrane adapter 1; Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells	0.880
BBOX1	TRIM34	ENSP00000263182	ENSP00000422947	Gamma-butyrobetaine dioxygenase; Catalyzes the formation of L-carnitine from gamma- butyrobetaine; Belongs to the gamma-BBH/TMLD family	Tripartite motif containing 34; May function as antiviral protein and may contribute to the defense against retroviral infections; Belongs to the TRIM/RBCC family	0.580
BBOX1	TRIM5	ENSP00000263182	ENSP00000369373	Gamma-butyrobetaine dioxygenase; Catalyzes the formation of L-carnitine from gamma- butyrobetaine; Belongs to the gamma-BBH/TMLD family	Tripartite motif-containing protein 5; Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice. Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1-UBE2N (also [...]	0.714
BTBD1	BTBD2	ENSP00000261721	ENSP00000255608	BTB/POZ domain-containing protein 1; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; BTB domain containing	BTB/POZ domain-containing protein 2; BTB domain containing 2	0.915
BTBD1	ENSG00000258588	ENSP00000261721	ENSP00000346916	BTB/POZ domain-containing protein 1; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; BTB domain containing	Tripartite motif-containing protein 34; May function as antiviral protein and may contribute to the defense against retroviral infections; Belongs to the TRIM/RBCC family	0.470
BTBD1	TRIM34	ENSP00000261721	ENSP00000422947	BTB/POZ domain-containing protein 1; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; BTB domain containing	Tripartite motif containing 34; May function as antiviral protein and may contribute to the defense against retroviral infections; Belongs to the TRIM/RBCC family	0.470
BTBD1	TRIM5	ENSP00000261721	ENSP00000369373	BTB/POZ domain-containing protein 1; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; BTB domain containing	Tripartite motif-containing protein 5; Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice. Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1-UBE2N (also [...]	0.931
BTBD2	BTBD1	ENSP00000255608	ENSP00000261721	BTB/POZ domain-containing protein 2; BTB domain containing 2	BTB/POZ domain-containing protein 1; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; BTB domain containing	0.915
BTBD2	ENSG00000258588	ENSP00000255608	ENSP00000346916	BTB/POZ domain-containing protein 2; BTB domain containing 2	Tripartite motif-containing protein 34; May function as antiviral protein and may contribute to the defense against retroviral infections; Belongs to the TRIM/RBCC family	0.470
BTBD2	TRIM34	ENSP00000255608	ENSP00000422947	BTB/POZ domain-containing protein 2; BTB domain containing 2	Tripartite motif containing 34; May function as antiviral protein and may contribute to the defense against retroviral infections; Belongs to the TRIM/RBCC family	0.470
BTBD2	TRIM5	ENSP00000255608	ENSP00000369373	BTB/POZ domain-containing protein 2; BTB domain containing 2	Tripartite motif-containing protein 5; Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice. Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1-UBE2N (also [...]	0.931
ENSG00000258588	BBOX1	ENSP00000346916	ENSP00000263182	Tripartite motif-containing protein 34; May function as antiviral protein and may contribute to the defense against retroviral infections; Belongs to the TRIM/RBCC family	Gamma-butyrobetaine dioxygenase; Catalyzes the formation of L-carnitine from gamma- butyrobetaine; Belongs to the gamma-BBH/TMLD family	0.587
ENSG00000258588	BTBD1	ENSP00000346916	ENSP00000261721	Tripartite motif-containing protein 34; May function as antiviral protein and may contribute to the defense against retroviral infections; Belongs to the TRIM/RBCC family	BTB/POZ domain-containing protein 1; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; BTB domain containing	0.470
ENSG00000258588	BTBD2	ENSP00000346916	ENSP00000255608	Tripartite motif-containing protein 34; May function as antiviral protein and may contribute to the defense against retroviral infections; Belongs to the TRIM/RBCC family	BTB/POZ domain-containing protein 2; BTB domain containing 2	0.470
ENSG00000258588	FLG2	ENSP00000346916	ENSP00000373370	Tripartite motif-containing protein 34; May function as antiviral protein and may contribute to the defense against retroviral infections; Belongs to the TRIM/RBCC family	Filaggrin-2; S100 fused type protein family; In the N-terminal section; belongs to the S-100 family	0.671
ENSG00000258588	OR52B6	ENSP00000346916	ENSP00000341581	Tripartite motif-containing protein 34; May function as antiviral protein and may contribute to the defense against retroviral infections; Belongs to the TRIM/RBCC family	Olfactory receptor 52B6; Odorant receptor; Olfactory receptors, family 52	0.447
ENSG00000258588	OR52H1	ENSP00000346916	ENSP00000326259	Tripartite motif-containing protein 34; May function as antiviral protein and may contribute to the defense against retroviral infections; Belongs to the TRIM/RBCC family	Olfactory receptor 52H1; Odorant receptor; Olfactory receptors, family 52	0.418
ENSG00000258588	TMLHE	ENSP00000346916	ENSP00000335261	Tripartite motif-containing protein 34; May function as antiviral protein and may contribute to the defense against retroviral infections; Belongs to the TRIM/RBCC family	Trimethyllysine dioxygenase, mitochondrial; Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML); Belongs to the gamma-BBH/TMLD family	0.481
ENSG00000258588	TRAT1	ENSP00000346916	ENSP00000295756	Tripartite motif-containing protein 34; May function as antiviral protein and may contribute to the defense against retroviral infections; Belongs to the TRIM/RBCC family	T-cell receptor-associated transmembrane adapter 1; Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells	0.719

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