| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADAD1 | ANKRD50 | ENSP00000296513 | ENSP00000425658 | Adenosine deaminase domain-containing protein 1; Plays a role in spermatogenesis. Binds to RNA but not to DNA (By similarity); Adenosine deaminases acting on RNA | Ankyrin repeat domain-containing protein 50; Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1; Ankyrin repeat domain containing | 0.645 |
| ADAD1 | ARL9 | ENSP00000296513 | ENSP00000353210 | Adenosine deaminase domain-containing protein 1; Plays a role in spermatogenesis. Binds to RNA but not to DNA (By similarity); Adenosine deaminases acting on RNA | ADP-ribosylation factor-like protein 9; ADP ribosylation factor like GTPase 9; ARF GTPase family | 0.662 |
| ADAD1 | SRP72 | ENSP00000296513 | ENSP00000342181 | Adenosine deaminase domain-containing protein 1; Plays a role in spermatogenesis. Binds to RNA but not to DNA (By similarity); Adenosine deaminases acting on RNA | Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. Binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function; Belongs to the SRP72 family | 0.514 |
| ADAD1 | TAPT1 | ENSP00000296513 | ENSP00000385347 | Adenosine deaminase domain-containing protein 1; Plays a role in spermatogenesis. Binds to RNA but not to DNA (By similarity); Adenosine deaminases acting on RNA | Transmembrane anterior posterior transformation protein 1 homolog; Plays a role in primary cilia formation. May act as a downstream effector of HOXC8 possibly by transducing or transmitting extracellular information required for axial skeletal patterning during development (By similarity). May be involved in cartilage and bone development (By similarity). May play a role in the differentiation of cranial neural crest cells (By similarity) | 0.545 |
| ADAD1 | TMEM33 | ENSP00000296513 | ENSP00000422473 | Adenosine deaminase domain-containing protein 1; Plays a role in spermatogenesis. Binds to RNA but not to DNA (By similarity); Adenosine deaminases acting on RNA | Transmembrane protein 33; Acts as a regulator of the tubular endoplasmic reticulum (ER) network. Suppresses the RTN3/4-induced formation of the ER tubules. Positively regulates PERK-mediated and IRE1-mediated unfolded protein response signaling | 0.660 |
| ANKRD50 | ADAD1 | ENSP00000425658 | ENSP00000296513 | Ankyrin repeat domain-containing protein 50; Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1; Ankyrin repeat domain containing | Adenosine deaminase domain-containing protein 1; Plays a role in spermatogenesis. Binds to RNA but not to DNA (By similarity); Adenosine deaminases acting on RNA | 0.645 |
| ANKRD50 | ARL9 | ENSP00000425658 | ENSP00000353210 | Ankyrin repeat domain-containing protein 50; Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1; Ankyrin repeat domain containing | ADP-ribosylation factor-like protein 9; ADP ribosylation factor like GTPase 9; ARF GTPase family | 0.735 |
| ANKRD50 | SRP72 | ENSP00000425658 | ENSP00000342181 | Ankyrin repeat domain-containing protein 50; Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1; Ankyrin repeat domain containing | Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. Binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function; Belongs to the SRP72 family | 0.568 |
| ANKRD50 | TAPT1 | ENSP00000425658 | ENSP00000385347 | Ankyrin repeat domain-containing protein 50; Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1; Ankyrin repeat domain containing | Transmembrane anterior posterior transformation protein 1 homolog; Plays a role in primary cilia formation. May act as a downstream effector of HOXC8 possibly by transducing or transmitting extracellular information required for axial skeletal patterning during development (By similarity). May be involved in cartilage and bone development (By similarity). May play a role in the differentiation of cranial neural crest cells (By similarity) | 0.628 |
| ANKRD50 | TMEM33 | ENSP00000425658 | ENSP00000422473 | Ankyrin repeat domain-containing protein 50; Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1; Ankyrin repeat domain containing | Transmembrane protein 33; Acts as a regulator of the tubular endoplasmic reticulum (ER) network. Suppresses the RTN3/4-induced formation of the ER tubules. Positively regulates PERK-mediated and IRE1-mediated unfolded protein response signaling | 0.739 |
| ARL9 | ADAD1 | ENSP00000353210 | ENSP00000296513 | ADP-ribosylation factor-like protein 9; ADP ribosylation factor like GTPase 9; ARF GTPase family | Adenosine deaminase domain-containing protein 1; Plays a role in spermatogenesis. Binds to RNA but not to DNA (By similarity); Adenosine deaminases acting on RNA | 0.662 |
| ARL9 | ANKRD50 | ENSP00000353210 | ENSP00000425658 | ADP-ribosylation factor-like protein 9; ADP ribosylation factor like GTPase 9; ARF GTPase family | Ankyrin repeat domain-containing protein 50; Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1; Ankyrin repeat domain containing | 0.735 |
| ARL9 | SRP72 | ENSP00000353210 | ENSP00000342181 | ADP-ribosylation factor-like protein 9; ADP ribosylation factor like GTPase 9; ARF GTPase family | Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. Binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function; Belongs to the SRP72 family | 0.615 |
| ARL9 | TAPT1 | ENSP00000353210 | ENSP00000385347 | ADP-ribosylation factor-like protein 9; ADP ribosylation factor like GTPase 9; ARF GTPase family | Transmembrane anterior posterior transformation protein 1 homolog; Plays a role in primary cilia formation. May act as a downstream effector of HOXC8 possibly by transducing or transmitting extracellular information required for axial skeletal patterning during development (By similarity). May be involved in cartilage and bone development (By similarity). May play a role in the differentiation of cranial neural crest cells (By similarity) | 0.602 |
| ARL9 | TMEM33 | ENSP00000353210 | ENSP00000422473 | ADP-ribosylation factor-like protein 9; ADP ribosylation factor like GTPase 9; ARF GTPase family | Transmembrane protein 33; Acts as a regulator of the tubular endoplasmic reticulum (ER) network. Suppresses the RTN3/4-induced formation of the ER tubules. Positively regulates PERK-mediated and IRE1-mediated unfolded protein response signaling | 0.728 |
| BEND4 | DCAF4L1 | ENSP00000421169 | ENSP00000327796 | BEN domain containing 4 | DDB1- and CUL4-associated factor 4-like protein 1; DDB1 and CUL4 associated factor 4 like 1; WD repeat domain containing | 0.675 |
| BEND4 | TMEM33 | ENSP00000421169 | ENSP00000422473 | BEN domain containing 4 | Transmembrane protein 33; Acts as a regulator of the tubular endoplasmic reticulum (ER) network. Suppresses the RTN3/4-induced formation of the ER tubules. Positively regulates PERK-mediated and IRE1-mediated unfolded protein response signaling | 0.659 |
| DCAF4L1 | BEND4 | ENSP00000327796 | ENSP00000421169 | DDB1- and CUL4-associated factor 4-like protein 1; DDB1 and CUL4 associated factor 4 like 1; WD repeat domain containing | BEN domain containing 4 | 0.675 |
| DCAF4L1 | TMEM33 | ENSP00000327796 | ENSP00000422473 | DDB1- and CUL4-associated factor 4-like protein 1; DDB1 and CUL4 associated factor 4 like 1; WD repeat domain containing | Transmembrane protein 33; Acts as a regulator of the tubular endoplasmic reticulum (ER) network. Suppresses the RTN3/4-induced formation of the ER tubules. Positively regulates PERK-mediated and IRE1-mediated unfolded protein response signaling | 0.729 |
| RTN1 | RTN4 | ENSP00000267484 | ENSP00000337838 | Reticulon-1; May be involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells | Reticulon-4; Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Regulates neurite fasciculation, branching and extension in the developing nervous system. Involved in down-regulation of growth, stabilization of wiring and restriction of plasticity in the adult CNS. Regulates the radial migration of cortical neurons via an RTN4R-LINGO1 containing receptor complex (By similarity). Isoform 2 reduces the anti-apoptotic activity of Bcl-xl and Bcl-2. This is likely consecutive to thei [...] | 0.678 |
