• Version:
  • 11.0 [archived version]
STRINGSTRING
SH3D21 SH3D21 NADK2 NADK2 ZNF211 ZNF211 DBX2 DBX2 ZNF608 ZNF608 RANBP3L RANBP3L PDCD11 PDCD11 ZNF25 ZNF25 TRIM73 TRIM73 FAM181A FAM181A TRIM74 TRIM74
"RANBP3L" - Ran-binding protein 3-like in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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RANBP3LRan-binding protein 3-like; Nuclear export factor for BMP-specific SMAD1/5/8 that plays a critical role in terminating BMP signaling and regulating mesenchymal stem cell differentiation by blocking osteoblast differentiation to promote myogenic differention. Directly recognizes dephosphorylated SMAD1/5/8 and mediates their nuclear export in a Ran-dependent manner (490 aa)    
Predicted Functional Partners:
PDCD11
Protein RRP5 homolog; Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA; Minor histocompatibility antigens (1871 aa)
     
   
  0.701
ZNF25
Zinc finger protein 25; May be involved in transcriptional regulation; Zinc fingers C2H2-type (456 aa)
     
   
  0.575
ZNF211
Zinc finger protein 211; Zinc fingers C2H2-type (629 aa)
           
  0.572
FAM181A
Protein FAM181A; Family with sequence similarity 181 member A (354 aa)
     
   
  0.562
SH3D21
SH3 domain containing 21 (645 aa)
           
  0.558
TRIM74
Tripartite motif containing 74; Belongs to the TRIM/RBCC family (250 aa)
           
  0.552
ZNF608
Zinc finger protein 608; Transcription factor, which represses ZNF609 transcription; Zinc fingers C2H2-type (1512 aa)
           
  0.533
TRIM73
Tripartite motif containing 73; Belongs to the TRIM/RBCC family (250 aa)
           
  0.530
NADK2
NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor. Also has weak NADH kinase activity in vitro; however NADH kinase activity is much weaker than the NAD(+) kinase activity and may not be relevant in vivo (442 aa)
           
  0.524
DBX2
Homeobox protein DBX2; NKL subclass homeoboxes and pseudogenes (339 aa)
     
   
  0.521
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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