| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CFAP221 | SH3D21 | ENSP00000393222 | ENSP00000421294 | Cilia- and flagella-associated protein 221; May play a role in cilium morphogenesis; Cilia and flagella associated | SH3 domain containing 21 | 0.519 |
| CKAP4 | LOC646862 | ENSP00000367265 | ENSP00000470441 | Cytoskeleton-associated protein 4; High-affinity epithelial cell surface receptor for APF | RING finger protein 225; Uncharacterized protein LOC646862 | 0.457 |
| CKAP4 | SCEL | ENSP00000367265 | ENSP00000302579 | Cytoskeleton-associated protein 4; High-affinity epithelial cell surface receptor for APF | Sciellin; May function in the assembly or regulation of proteins in the cornified envelope. The LIM domain may be involved in homotypic or heterotypic associations and may function to localize sciellin to the cornified envelope | 0.434 |
| CKAP4 | SH3D21 | ENSP00000367265 | ENSP00000421294 | Cytoskeleton-associated protein 4; High-affinity epithelial cell surface receptor for APF | SH3 domain containing 21 | 0.446 |
| EVA1B | SH3D21 | ENSP00000270824 | ENSP00000421294 | Eva-1 homolog B; Belongs to the EVA1 family | SH3 domain containing 21 | 0.543 |
| GDPD4 | NADK2 | ENSP00000320815 | ENSP00000371362 | Glycerophosphodiester phosphodiesterase domain containing 4; Belongs to the glycerophosphoryl diester phosphodiesterase family | NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor. Also has weak NADH kinase activity in vitro; however NADH kinase activity is much weaker than the NAD(+) kinase activity and may not be relevant in vivo | 0.473 |
| GDPD4 | RANBP3L | ENSP00000320815 | ENSP00000421853 | Glycerophosphodiester phosphodiesterase domain containing 4; Belongs to the glycerophosphoryl diester phosphodiesterase family | Ran-binding protein 3-like; Nuclear export factor for BMP-specific SMAD1/5/8 that plays a critical role in terminating BMP signaling and regulating mesenchymal stem cell differentiation by blocking osteoblast differentiation to promote myogenic differention. Directly recognizes dephosphorylated SMAD1/5/8 and mediates their nuclear export in a Ran-dependent manner | 0.451 |
| GDPD4 | SH3D21 | ENSP00000320815 | ENSP00000421294 | Glycerophosphodiester phosphodiesterase domain containing 4; Belongs to the glycerophosphoryl diester phosphodiesterase family | SH3 domain containing 21 | 0.527 |
| LOC646862 | CKAP4 | ENSP00000470441 | ENSP00000367265 | RING finger protein 225; Uncharacterized protein LOC646862 | Cytoskeleton-associated protein 4; High-affinity epithelial cell surface receptor for APF | 0.457 |
| LOC646862 | SH3D21 | ENSP00000470441 | ENSP00000421294 | RING finger protein 225; Uncharacterized protein LOC646862 | SH3 domain containing 21 | 0.452 |
| NADK2 | GDPD4 | ENSP00000371362 | ENSP00000320815 | NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor. Also has weak NADH kinase activity in vitro; however NADH kinase activity is much weaker than the NAD(+) kinase activity and may not be relevant in vivo | Glycerophosphodiester phosphodiesterase domain containing 4; Belongs to the glycerophosphoryl diester phosphodiesterase family | 0.473 |
| NADK2 | RANBP3L | ENSP00000371362 | ENSP00000421853 | NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor. Also has weak NADH kinase activity in vitro; however NADH kinase activity is much weaker than the NAD(+) kinase activity and may not be relevant in vivo | Ran-binding protein 3-like; Nuclear export factor for BMP-specific SMAD1/5/8 that plays a critical role in terminating BMP signaling and regulating mesenchymal stem cell differentiation by blocking osteoblast differentiation to promote myogenic differention. Directly recognizes dephosphorylated SMAD1/5/8 and mediates their nuclear export in a Ran-dependent manner | 0.524 |
| NADK2 | SH3D21 | ENSP00000371362 | ENSP00000421294 | NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor. Also has weak NADH kinase activity in vitro; however NADH kinase activity is much weaker than the NAD(+) kinase activity and may not be relevant in vivo | SH3 domain containing 21 | 0.574 |
| RANBP3L | GDPD4 | ENSP00000421853 | ENSP00000320815 | Ran-binding protein 3-like; Nuclear export factor for BMP-specific SMAD1/5/8 that plays a critical role in terminating BMP signaling and regulating mesenchymal stem cell differentiation by blocking osteoblast differentiation to promote myogenic differention. Directly recognizes dephosphorylated SMAD1/5/8 and mediates their nuclear export in a Ran-dependent manner | Glycerophosphodiester phosphodiesterase domain containing 4; Belongs to the glycerophosphoryl diester phosphodiesterase family | 0.451 |
| RANBP3L | NADK2 | ENSP00000421853 | ENSP00000371362 | Ran-binding protein 3-like; Nuclear export factor for BMP-specific SMAD1/5/8 that plays a critical role in terminating BMP signaling and regulating mesenchymal stem cell differentiation by blocking osteoblast differentiation to promote myogenic differention. Directly recognizes dephosphorylated SMAD1/5/8 and mediates their nuclear export in a Ran-dependent manner | NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor. Also has weak NADH kinase activity in vitro; however NADH kinase activity is much weaker than the NAD(+) kinase activity and may not be relevant in vivo | 0.524 |
| RANBP3L | SH3D21 | ENSP00000421853 | ENSP00000421294 | Ran-binding protein 3-like; Nuclear export factor for BMP-specific SMAD1/5/8 that plays a critical role in terminating BMP signaling and regulating mesenchymal stem cell differentiation by blocking osteoblast differentiation to promote myogenic differention. Directly recognizes dephosphorylated SMAD1/5/8 and mediates their nuclear export in a Ran-dependent manner | SH3 domain containing 21 | 0.558 |
| RPS27A | SH3D21 | ENSP00000272317 | ENSP00000421294 | Ubiquitin-40S ribosomal protein S27a; Ubiquitin- Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked- Lys-6-linked may be inv [...] | SH3 domain containing 21 | 0.510 |
| RPS27A | UBA52 | ENSP00000272317 | ENSP00000388107 | Ubiquitin-40S ribosomal protein S27a; Ubiquitin- Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked- Lys-6-linked may be inv [...] | Ubiquitin-60S ribosomal protein L40; Ubiquitin- Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked- Lys-6-linked may be invo [...] | 0.999 |
| SCEL | CKAP4 | ENSP00000302579 | ENSP00000367265 | Sciellin; May function in the assembly or regulation of proteins in the cornified envelope. The LIM domain may be involved in homotypic or heterotypic associations and may function to localize sciellin to the cornified envelope | Cytoskeleton-associated protein 4; High-affinity epithelial cell surface receptor for APF | 0.434 |
| SCEL | SH3D21 | ENSP00000302579 | ENSP00000421294 | Sciellin; May function in the assembly or regulation of proteins in the cornified envelope. The LIM domain may be involved in homotypic or heterotypic associations and may function to localize sciellin to the cornified envelope | SH3 domain containing 21 | 0.456 |
