• Version:
  • 11.0 [archived version]
STRINGSTRING
PTPN3 PTPN3 ZNF736 ZNF736 FAM218A FAM218A TRIM42 TRIM42 TMEM192 TMEM192 TRIM60 TRIM60 TRAT1 TRAT1 TRIM36 TRIM36 KIF3A KIF3A KIF3B KIF3B KIFAP3 KIFAP3
"TRIM60" - Tripartite motif containing 60 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
TRIM60Tripartite motif containing 60; Belongs to the TRIM/RBCC family (471 aa)    
Predicted Functional Partners:
ZNF736
Zinc finger protein 736; May be involved in transcriptional regulation; Zinc fingers C2H2-type (427 aa)
     
 
  0.699
FAM218A
Protein FAM218A; Family with sequence similarity 218 member A (157 aa)
           
  0.588
KIF3B
Kinesin-like protein KIF3B; Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro (By similarity); Kinesins (747 aa)
       
 
  0.574
KIF3A
Kinesin-like protein KIF3A; Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. Plays a role in primary cilia formation. Plays a role in centriole cohesion and subdistal appendage organization and function. Regulates the formation of the subdistal appendage via recruitement of DCTN1 to the centriole. Also required for ciliary basal feet formation and microtubule anchoring to mother centriole; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Kinesin II subfamily (726 aa)
       
 
  0.539
TRIM42
Tripartite motif-containing protein 42; Protein phosphatase 1 regulatory subunits; Belongs to the TRIM/RBCC family (723 aa)
           
  0.537
TMEM192
Transmembrane protein 192 (271 aa)
           
  0.513
TRIM36
E3 ubiquitin-protein ligase TRIM36; E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Involved in chromosome segregation and cell cycle regulation. May play a role in the acrosome reaction and fertilization; Belongs to the TRIM/RBCC family (728 aa)
           
  0.481
TRAT1
T-cell receptor-associated transmembrane adapter 1; Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells (186 aa)
           
  0.473
KIFAP3
Kinesin-associated protein 3; Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Binds to the tail domain of the KIF3A/KIF3B heterodimer to form a heterotrimeric KIF3 complex and may regulate the membrane binding of this complex (By similarity); Armadillo-like helical domain containing (792 aa)
           
  0.469
PTPN3
Tyrosine-protein phosphatase non-receptor type 3; May act at junctions between the membrane and the cytoskeleton. Possesses tyrosine phosphatase activity; FERM domain containing (913 aa)
           
  0.467
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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