node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ERLEC1 | ZNF181 | ENSP00000185150 | ENSP00000420727 | Endoplasmic reticulum lectin 1; Probable lectin that binds selectively to improperly folded lumenal proteins. May function in endoplasmic reticulum quality control and endoplasmic reticulum-associated degradation (ERAD) of both non-glycosylated proteins and glycoproteins; MRH domain containing | Zinc finger protein 181; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.457 |
GABPB1 | MORF4L2 | ENSP00000220429 | ENSP00000394417 | GA-binding protein subunit beta-1; Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene; Ankyrin repeat domain containing | Mortality factor 4-like protein 2; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative [...] | 0.404 |
GABPB1 | ZMAT5 | ENSP00000220429 | ENSP00000344241 | GA-binding protein subunit beta-1; Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene; Ankyrin repeat domain containing | Zinc finger matrin-type 5; U11/U12 di-snRNP | 0.414 |
GABPB1 | ZNF181 | ENSP00000220429 | ENSP00000420727 | GA-binding protein subunit beta-1; Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene; Ankyrin repeat domain containing | Zinc finger protein 181; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.435 |
LSM14A | UBA2 | ENSP00000446271 | ENSP00000246548 | Protein LSM14 homolog A; Essential for formation of P-bodies, cytoplasmic structures that provide storage sites for non-translating mRNAs; LSm proteins | SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2; Ubiquitin like modifier activating enzymes | 0.803 |
LSM14A | ZNF181 | ENSP00000446271 | ENSP00000420727 | Protein LSM14 homolog A; Essential for formation of P-bodies, cytoplasmic structures that provide storage sites for non-translating mRNAs; LSm proteins | Zinc finger protein 181; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.443 |
MORF4L2 | GABPB1 | ENSP00000394417 | ENSP00000220429 | Mortality factor 4-like protein 2; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative [...] | GA-binding protein subunit beta-1; Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene; Ankyrin repeat domain containing | 0.404 |
MORF4L2 | ZMAT5 | ENSP00000394417 | ENSP00000344241 | Mortality factor 4-like protein 2; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative [...] | Zinc finger matrin-type 5; U11/U12 di-snRNP | 0.507 |
MORF4L2 | ZNF181 | ENSP00000394417 | ENSP00000420727 | Mortality factor 4-like protein 2; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative [...] | Zinc finger protein 181; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.468 |
SCGB2B2 | UBA2 | ENSP00000469876 | ENSP00000246548 | Secretoglobin family 2B member 2; Secretoglobins | SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2; Ubiquitin like modifier activating enzymes | 0.491 |
SCGB2B2 | ZNF181 | ENSP00000469876 | ENSP00000420727 | Secretoglobin family 2B member 2; Secretoglobins | Zinc finger protein 181; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.477 |
UBA2 | LSM14A | ENSP00000246548 | ENSP00000446271 | SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2; Ubiquitin like modifier activating enzymes | Protein LSM14 homolog A; Essential for formation of P-bodies, cytoplasmic structures that provide storage sites for non-translating mRNAs; LSm proteins | 0.803 |
UBA2 | SCGB2B2 | ENSP00000246548 | ENSP00000469876 | SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2; Ubiquitin like modifier activating enzymes | Secretoglobin family 2B member 2; Secretoglobins | 0.491 |
UBA2 | ZNF181 | ENSP00000246548 | ENSP00000420727 | SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2; Ubiquitin like modifier activating enzymes | Zinc finger protein 181; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.431 |
ZDHHC11 | ZNF181 | ENSP00000283441 | ENSP00000420727 | Probable palmitoyltransferase ZDHHC11; Zinc finger DHHC-type containing 11; Belongs to the DHHC palmitoyltransferase family | Zinc finger protein 181; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.435 |
ZMAT5 | GABPB1 | ENSP00000344241 | ENSP00000220429 | Zinc finger matrin-type 5; U11/U12 di-snRNP | GA-binding protein subunit beta-1; Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene; Ankyrin repeat domain containing | 0.414 |
ZMAT5 | MORF4L2 | ENSP00000344241 | ENSP00000394417 | Zinc finger matrin-type 5; U11/U12 di-snRNP | Mortality factor 4-like protein 2; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative [...] | 0.507 |
ZMAT5 | ZNF181 | ENSP00000344241 | ENSP00000420727 | Zinc finger matrin-type 5; U11/U12 di-snRNP | Zinc finger protein 181; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.575 |
ZNF181 | ERLEC1 | ENSP00000420727 | ENSP00000185150 | Zinc finger protein 181; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Endoplasmic reticulum lectin 1; Probable lectin that binds selectively to improperly folded lumenal proteins. May function in endoplasmic reticulum quality control and endoplasmic reticulum-associated degradation (ERAD) of both non-glycosylated proteins and glycoproteins; MRH domain containing | 0.457 |
ZNF181 | GABPB1 | ENSP00000420727 | ENSP00000220429 | Zinc finger protein 181; May be involved in transcriptional regulation; Zinc fingers C2H2-type | GA-binding protein subunit beta-1; Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene; Ankyrin repeat domain containing | 0.435 |