CYLC2 protein (human) - STRING database

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CYLC2

Cylicin-2; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation (348 aa)

Predicted Functional Partners:

CCIN

0.907

UTP3

0.738

ZPBP2

0.677

SERPINA10

0.623

CABYR

0.577

OR2T10

0.573

OR52M1

0.572

PGLYRP2

0.536

SPACA1

0.530

TPP2

0.519

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CABYR	CYLC2	ENSP00000483621	ENSP00000420256	Calcium-binding tyrosine phosphorylation-regulated protein; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium	Cylicin-2; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation	0.577
CABYR	UTP3	ENSP00000483621	ENSP00000254803	Calcium-binding tyrosine phosphorylation-regulated protein; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium	Something about silencing protein 10; Essential for gene silencing- has a role in the structure of silenced chromatin. Plays a role in the developing brain (By similarity); Belongs to the SAS10 family	0.472
CABYR	ZPBP2	ENSP00000483621	ENSP00000335384	Calcium-binding tyrosine phosphorylation-regulated protein; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium	Zona pellucida-binding protein 2; Is implicated in sperm-oocyte interaction during fertilization; Immunoglobulin like domain containing	0.509
CCIN	CYLC2	ENSP00000334996	ENSP00000420256	Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation; BTB domain containing	Cylicin-2; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation	0.907
CYLC2	CABYR	ENSP00000420256	ENSP00000483621	Cylicin-2; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation	Calcium-binding tyrosine phosphorylation-regulated protein; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium	0.577
CYLC2	CCIN	ENSP00000420256	ENSP00000334996	Cylicin-2; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation	Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation; BTB domain containing	0.907
CYLC2	OR2T10	ENSP00000420256	ENSP00000329210	Cylicin-2; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation	Olfactory receptor 2T10; Odorant receptor; Olfactory receptors, family 2	0.573
CYLC2	OR52M1	ENSP00000420256	ENSP00000353343	Cylicin-2; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation	Olfactory receptor 52M1; Odorant receptor; Olfactory receptors, family 52	0.572
CYLC2	PGLYRP2	ENSP00000420256	ENSP00000345968	Cylicin-2; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation	N-acetylmuramoyl-L-alanine amidase; May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity; Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family	0.536
CYLC2	SERPINA10	ENSP00000420256	ENSP00000261994	Cylicin-2; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation	Protein Z-dependent protease inhibitor; Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids. Also inhibits factor XIa in the absence of cofactors; Belongs to the serpin family	0.623
CYLC2	SPACA1	ENSP00000420256	ENSP00000237201	Cylicin-2; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation	Sperm acrosome membrane-associated protein 1; May be involved in sperm-egg fusion	0.530
CYLC2	TPP2	ENSP00000420256	ENSP00000365233	Cylicin-2; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation	Tripeptidyl-peptidase 2; Component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway. May be able to complement the 26S proteasome function to some extent under conditions in which the latter is inhibited. Stimulates adipogenesis (By similarity)	0.519
CYLC2	UTP3	ENSP00000420256	ENSP00000254803	Cylicin-2; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation	Something about silencing protein 10; Essential for gene silencing- has a role in the structure of silenced chromatin. Plays a role in the developing brain (By similarity); Belongs to the SAS10 family	0.738
CYLC2	ZPBP2	ENSP00000420256	ENSP00000335384	Cylicin-2; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation	Zona pellucida-binding protein 2; Is implicated in sperm-oocyte interaction during fertilization; Immunoglobulin like domain containing	0.677
OR2T10	CYLC2	ENSP00000329210	ENSP00000420256	Olfactory receptor 2T10; Odorant receptor; Olfactory receptors, family 2	Cylicin-2; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation	0.573
OR52M1	CYLC2	ENSP00000353343	ENSP00000420256	Olfactory receptor 52M1; Odorant receptor; Olfactory receptors, family 52	Cylicin-2; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation	0.572
PGLYRP2	CYLC2	ENSP00000345968	ENSP00000420256	N-acetylmuramoyl-L-alanine amidase; May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity; Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family	Cylicin-2; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation	0.536
PGLYRP2	SERPINA10	ENSP00000345968	ENSP00000261994	N-acetylmuramoyl-L-alanine amidase; May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity; Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family	Protein Z-dependent protease inhibitor; Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids. Also inhibits factor XIa in the absence of cofactors; Belongs to the serpin family	0.472
SERPINA10	CYLC2	ENSP00000261994	ENSP00000420256	Protein Z-dependent protease inhibitor; Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids. Also inhibits factor XIa in the absence of cofactors; Belongs to the serpin family	Cylicin-2; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation	0.623
SERPINA10	PGLYRP2	ENSP00000261994	ENSP00000345968	Protein Z-dependent protease inhibitor; Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids. Also inhibits factor XIa in the absence of cofactors; Belongs to the serpin family	N-acetylmuramoyl-L-alanine amidase; May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity; Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family	0.472

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