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STRINGSTRING
MYO1B MYO1B CARF CARF CELA1 CELA1 PRSS3P2 PRSS3P2 CPA5 CPA5 PRSS1 PRSS1 TSGA13 TSGA13 CTRB2 CTRB2 CTRB1 CTRB1 SSMEM1 SSMEM1 CELA3B CELA3B
"CPA5" - M14 carboxypeptidases in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CPA5M14 carboxypeptidases; Belongs to the peptidase M14 family (436 aa)    
Predicted Functional Partners:
CTRB2
Chymotrypsinogen B2; Belongs to the peptidase S1 family (263 aa)
      
 
  0.726
CTRB1
Chymotrypsinogen B1; Belongs to the peptidase S1 family (263 aa)
      
 
  0.695
CARF
Calcium-responsive transcription factor; Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription. Binds to the consensus calcium-response element CaRE1 5’-CTATTTCGAG-3’ sequence (725 aa)
            
  0.665
CELA3B
Chymotrypsin-like elastase family member 3B; Efficient protease with alanine specificity but only little elastolytic activity (270 aa)
      
 
  0.612
SSMEM1
Serine rich single-pass membrane protein 1 (244 aa)
      
   
  0.581
TSGA13
Testis-specific gene 13 protein; Testis specific 13 (275 aa)
            
  0.576
PRSS3P2
Trypsin-2; In the ileum, may be involved in defensin processing, including DEFA5; Belongs to the peptidase S1 family (261 aa)
      
 
  0.566
CELA1
Chymotrypsin-like elastase family member 1; Acts upon elastin (258 aa)
      
 
  0.546
PRSS1
Trypsin-1; Has activity against the synthetic substrates Boc-Phe- Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val- Pro-Arg-Mec. The single-chain form is more active than the two- chain form against all of these substrates; Belongs to the peptidase S1 family (247 aa)
      
 
  0.526
MYO1B
Unconventional myosin-Ib; Motor protein that may participate in process critical to neuronal development and function such as cell migration, neurite outgrowth and vesicular transport; Myosins, class I (1136 aa)
            
  0.512
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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