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STRINGSTRING
ZNF280A ZNF280A ZNF280B ZNF280B POM121L1P POM121L1P ALPL ALPL ALPP ALPP GGTLC2 GGTLC2 ALPPL2 ALPPL2 ALPI ALPI GGT6 GGT6 LOR LOR TGM3 TGM3
"GGTLC2" - Gamma-glutamyltransferase light chain 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
GGTLC2Gamma-glutamyltransferase light chain 2; Belongs to the gamma-glutamyltransferase family (218 aa)    
Predicted Functional Partners:
GGT6
Glutathione hydrolase 6; Cleaves glutathione conjugates; Gamma-glutamyltransferases (499 aa)
            
  0.779
TGM3
Protein-glutamine gamma-glutamyltransferase E; Catalyzes the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in various proteins, as well as the conjugation of polyamines to proteins. Involved in the formation of the cornified envelope (CE), a specialized component consisting of covalent cross-links of proteins beneath the plasma membrane of terminally differentiated keratinocytes. Catalyzes small proline-rich proteins (SPRR1 and SPRR2) and LOR cross-linking to form small interchain oligomers, which are further cross-linked by TGM1 onto the g [...] (693 aa)
            
  0.643
ALPPL2
Alkaline phosphatase, placental like 2 (532 aa)
        
 
  0.616
ALPI
Alkaline phosphatase, intestinal (528 aa)
        
 
  0.614
ALPP
Alkaline phosphatase, placental (535 aa)
        
 
  0.593
ZNF280A
Zinc finger protein 280A; May function as a transcription factor (542 aa)
            
  0.571
POM121L1P
annotation not available (429 aa)
            
  0.556
ALPL
Alkaline phosphatase, tissue-nonspecific isozyme; This isozyme may play a role in skeletal mineralization; Belongs to the alkaline phosphatase family (524 aa)
      
 
  0.555
ZNF280B
Zinc finger protein 280B; May function as a transcription factor (543 aa)
            
  0.530
LOR
Loricrin; Major keratinocyte cell envelope protein; Cornified envelope precursor family (312 aa)
            
  0.527
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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