node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABCB7 | ABCF2 | ENSP00000253577 | ENSP00000222388 | ATP-binding cassette sub-family B member 7, mitochondrial; Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins; ATP binding cassette subfamily B | ATP binding cassette subfamily F member 2 | 0.731 |
ABCB7 | FAM122B | ENSP00000253577 | ENSP00000419592 | ATP-binding cassette sub-family B member 7, mitochondrial; Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins; ATP binding cassette subfamily B | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family | 0.561 |
ABCB7 | THOC2 | ENSP00000253577 | ENSP00000245838 | ATP-binding cassette sub-family B member 7, mitochondrial; Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins; ATP binding cassette subfamily B | THO complex subunit 2; Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5’ end of the mRNA where it functions in mRNA export to the cyt [...] | 0.599 |
ABCF2 | ABCB7 | ENSP00000222388 | ENSP00000253577 | ATP binding cassette subfamily F member 2 | ATP-binding cassette sub-family B member 7, mitochondrial; Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins; ATP binding cassette subfamily B | 0.731 |
ABCF2 | FAM122B | ENSP00000222388 | ENSP00000419592 | ATP binding cassette subfamily F member 2 | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family | 0.560 |
APBA2 | FAM122A | ENSP00000453293 | ENSP00000377807 | Amyloid-beta A4 precursor protein-binding family A member 2; Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta; PDZ domain containing | Protein FAM122A; Family with sequence similarity 122A | 0.637 |
APBA2 | FAM122B | ENSP00000453293 | ENSP00000419592 | Amyloid-beta A4 precursor protein-binding family A member 2; Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta; PDZ domain containing | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family | 0.527 |
DDX26B | FAM122B | ENSP00000359788 | ENSP00000419592 | Integrator complex subunit 6-like; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family | 0.568 |
DDX26B | MUM1L1 | ENSP00000359788 | ENSP00000338641 | Integrator complex subunit 6-like; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B | PWWP domain-containing protein MUM1L1; PWWP domain containing; Belongs to the MUM1 family | 0.439 |
DDX26B | RBMX2 | ENSP00000359788 | ENSP00000339090 | Integrator complex subunit 6-like; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B | RNA binding motif protein, X-linked 2 | 0.627 |
FAM122A | APBA2 | ENSP00000377807 | ENSP00000453293 | Protein FAM122A; Family with sequence similarity 122A | Amyloid-beta A4 precursor protein-binding family A member 2; Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta; PDZ domain containing | 0.637 |
FAM122A | FAM122B | ENSP00000377807 | ENSP00000419592 | Protein FAM122A; Family with sequence similarity 122A | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family | 0.821 |
FAM122B | ABCB7 | ENSP00000419592 | ENSP00000253577 | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family | ATP-binding cassette sub-family B member 7, mitochondrial; Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins; ATP binding cassette subfamily B | 0.561 |
FAM122B | ABCF2 | ENSP00000419592 | ENSP00000222388 | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family | ATP binding cassette subfamily F member 2 | 0.560 |
FAM122B | APBA2 | ENSP00000419592 | ENSP00000453293 | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family | Amyloid-beta A4 precursor protein-binding family A member 2; Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta; PDZ domain containing | 0.527 |
FAM122B | DDX26B | ENSP00000419592 | ENSP00000359788 | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family | Integrator complex subunit 6-like; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B | 0.568 |
FAM122B | FAM122A | ENSP00000419592 | ENSP00000377807 | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family | Protein FAM122A; Family with sequence similarity 122A | 0.821 |
FAM122B | MUM1L1 | ENSP00000419592 | ENSP00000338641 | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family | PWWP domain-containing protein MUM1L1; PWWP domain containing; Belongs to the MUM1 family | 0.580 |
FAM122B | RBMX2 | ENSP00000419592 | ENSP00000339090 | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family | RNA binding motif protein, X-linked 2 | 0.634 |
FAM122B | RIN2 | ENSP00000419592 | ENSP00000255006 | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family | Ras and Rab interactor 2; Ras effector protein. May function as an upstream activator and/or downstream effector for RAB5B in endocytic pathway. May function as a guanine nucleotide exchange (GEF) of RAB5B, required for activating the RAB5 proteins by exchanging bound GDP for free GTP; Belongs to the RIN (Ras interaction/interference) family | 0.611 |