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  • 11.0 [archived version]
STRINGSTRING
FAM122A FAM122A APBA2 APBA2 UBE2Q1 UBE2Q1 ABCF2 ABCF2 FAM122B FAM122B RIN2 RIN2 ABCB7 ABCB7 THOC2 THOC2 MUM1L1 MUM1L1 RBMX2 RBMX2 DDX26B DDX26B
"FAM122B" - Protein FAM122B in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
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[Homology]
Score
FAM122BProtein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family (248 aa)    
Predicted Functional Partners:
FAM122A
Protein FAM122A; Family with sequence similarity 122A (287 aa)
       
 
0.821
RBMX2
RNA binding motif protein, X-linked 2 (322 aa)
     
   
  0.634
RIN2
Ras and Rab interactor 2; Ras effector protein. May function as an upstream activator and/or downstream effector for RAB5B in endocytic pathway. May function as a guanine nucleotide exchange (GEF) of RAB5B, required for activating the RAB5 proteins by exchanging bound GDP for free GTP; Belongs to the RIN (Ras interaction/interference) family (944 aa)
           
  0.611
MUM1L1
PWWP domain-containing protein MUM1L1; PWWP domain containing; Belongs to the MUM1 family (696 aa)
           
  0.580
DDX26B
Integrator complex subunit 6-like; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B (861 aa)
           
  0.568
ABCB7
ATP-binding cassette sub-family B member 7, mitochondrial; Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins; ATP binding cassette subfamily B (753 aa)
     
   
  0.561
ABCF2
ATP binding cassette subfamily F member 2 (634 aa)
           
  0.560
UBE2Q1
Ubiquitin-conjugating enzyme E2 Q1; Catalyzes the covalent attachment of ubiquitin to other proteins. May be involved in hormonal homeostasis in females. Involved in regulation of B4GALT1 cell surface expression, B4GALT1-mediated cell adhesion to laminin and embryoid body formation (By similarity); Ubiquitin conjugating enzymes E2 (422 aa)
           
  0.549
THOC2
THO complex subunit 2; Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5’ end of the mRNA where it functions in mRNA export to the cyt [...] (1593 aa)
     
   
  0.542
APBA2
Amyloid-beta A4 precursor protein-binding family A member 2; Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta; PDZ domain containing (749 aa)
           
  0.527
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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