node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALG11 | GXYLT1 | ENSP00000430236 | ENSP00000381666 | GDP-Man-Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase; Mannosyltransferase involved in the last steps of the synthesis of Man5GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum. Catalyzes the addition of the 4th and 5th mannose residues to the dolichol- linked oligosaccharide chain; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily | Glucoside xylosyltransferase 1; Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose | 0.444 |
ALG11 | UTP14A | ENSP00000430236 | ENSP00000377944 | GDP-Man-Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase; Mannosyltransferase involved in the last steps of the synthesis of Man5GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum. Catalyzes the addition of the 4th and 5th mannose residues to the dolichol- linked oligosaccharide chain; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily | U3 small nucleolar RNA-associated protein 14 homolog A; May be required for ribosome biogenesis | 0.612 |
ALG11 | UTP14C | ENSP00000430236 | ENSP00000428619 | GDP-Man-Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase; Mannosyltransferase involved in the last steps of the synthesis of Man5GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum. Catalyzes the addition of the 4th and 5th mannose residues to the dolichol- linked oligosaccharide chain; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily | U3 small nucleolar RNA-associated protein 14 homolog C; Essential for spermatogenesis. May be required specifically for ribosome biogenesis and hence protein synthesis during male meiosis (By similarity) | 0.667 |
ALG11 | ZNF782 | ENSP00000430236 | ENSP00000419397 | GDP-Man-Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase; Mannosyltransferase involved in the last steps of the synthesis of Man5GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum. Catalyzes the addition of the 4th and 5th mannose residues to the dolichol- linked oligosaccharide chain; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily | Zinc finger protein 782; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.449 |
C11orf94 | ERV3-1 | ENSP00000401498 | ENSP00000391594 | Uncharacterized protein C11orf94; Chromosome 11 open reading frame 94 | Endogenous retrovirus group 3 member 1 Env polyprotein; Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its fusogenic properties. It can inhibit cell growth through decrease expression of cyclin B1 and increased expression of p21 in vitro; Envelope ERV derived genes | 0.511 |
C11orf94 | NCKIPSD | ENSP00000401498 | ENSP00000294129 | Uncharacterized protein C11orf94; Chromosome 11 open reading frame 94 | NCK-interacting protein with SH3 domain; Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1). Induces microspike formation, in vivo (By similarity). In vitro, stimulates N-WASP- induced ARP2/3 complex activation in the absence of CDC42 (By similarity). May play an important role in the maintenance of sarcomeres and/or in the assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion. Plays a role in angiogenesis | 0.530 |
C11orf94 | OR2A2 | ENSP00000401498 | ENSP00000386209 | Uncharacterized protein C11orf94; Chromosome 11 open reading frame 94 | Olfactory receptor 2A2; Odorant receptor; Olfactory receptors, family 2 | 0.709 |
C11orf94 | ZNF782 | ENSP00000401498 | ENSP00000419397 | Uncharacterized protein C11orf94; Chromosome 11 open reading frame 94 | Zinc finger protein 782; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.708 |
ERV3-1 | C11orf94 | ENSP00000391594 | ENSP00000401498 | Endogenous retrovirus group 3 member 1 Env polyprotein; Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its fusogenic properties. It can inhibit cell growth through decrease expression of cyclin B1 and increased expression of p21 in vitro; Envelope ERV derived genes | Uncharacterized protein C11orf94; Chromosome 11 open reading frame 94 | 0.511 |
ERV3-1 | OR2A2 | ENSP00000391594 | ENSP00000386209 | Endogenous retrovirus group 3 member 1 Env polyprotein; Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its fusogenic properties. It can inhibit cell growth through decrease expression of cyclin B1 and increased expression of p21 in vitro; Envelope ERV derived genes | Olfactory receptor 2A2; Odorant receptor; Olfactory receptors, family 2 | 0.441 |
ERV3-1 | ZNF782 | ENSP00000391594 | ENSP00000419397 | Endogenous retrovirus group 3 member 1 Env polyprotein; Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its fusogenic properties. It can inhibit cell growth through decrease expression of cyclin B1 and increased expression of p21 in vitro; Envelope ERV derived genes | Zinc finger protein 782; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.472 |
GXYLT1 | ALG11 | ENSP00000381666 | ENSP00000430236 | Glucoside xylosyltransferase 1; Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose | GDP-Man-Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase; Mannosyltransferase involved in the last steps of the synthesis of Man5GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum. Catalyzes the addition of the 4th and 5th mannose residues to the dolichol- linked oligosaccharide chain; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily | 0.444 |
GXYLT1 | ZNF782 | ENSP00000381666 | ENSP00000419397 | Glucoside xylosyltransferase 1; Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose | Zinc finger protein 782; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.556 |
MYO3B | ZNF782 | ENSP00000386213 | ENSP00000419397 | Myosin-IIIb; Probable actin-based motor with a protein kinase activity. Required for normal cochlear hair bundle development and hearing. Plays an important role in the early steps of cochlear hair bundle morphogenesis. Influences the number and lengths of stereocilia to be produced and limits the growth of microvilli within the forming auditory hair bundles thereby contributing to the architecture of the hair bundle, including its staircase pattern. Involved in the elongation of actin in stereocilia tips by transporting the actin regulatory factor ESPN to the plus ends of actin filame [...] | Zinc finger protein 782; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.487 |
NCKIPSD | C11orf94 | ENSP00000294129 | ENSP00000401498 | NCK-interacting protein with SH3 domain; Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1). Induces microspike formation, in vivo (By similarity). In vitro, stimulates N-WASP- induced ARP2/3 complex activation in the absence of CDC42 (By similarity). May play an important role in the maintenance of sarcomeres and/or in the assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion. Plays a role in angiogenesis | Uncharacterized protein C11orf94; Chromosome 11 open reading frame 94 | 0.530 |
NCKIPSD | OR2A2 | ENSP00000294129 | ENSP00000386209 | NCK-interacting protein with SH3 domain; Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1). Induces microspike formation, in vivo (By similarity). In vitro, stimulates N-WASP- induced ARP2/3 complex activation in the absence of CDC42 (By similarity). May play an important role in the maintenance of sarcomeres and/or in the assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion. Plays a role in angiogenesis | Olfactory receptor 2A2; Odorant receptor; Olfactory receptors, family 2 | 0.448 |
NCKIPSD | ZNF782 | ENSP00000294129 | ENSP00000419397 | NCK-interacting protein with SH3 domain; Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1). Induces microspike formation, in vivo (By similarity). In vitro, stimulates N-WASP- induced ARP2/3 complex activation in the absence of CDC42 (By similarity). May play an important role in the maintenance of sarcomeres and/or in the assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion. Plays a role in angiogenesis | Zinc finger protein 782; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.474 |
OR2A2 | C11orf94 | ENSP00000386209 | ENSP00000401498 | Olfactory receptor 2A2; Odorant receptor; Olfactory receptors, family 2 | Uncharacterized protein C11orf94; Chromosome 11 open reading frame 94 | 0.709 |
OR2A2 | ERV3-1 | ENSP00000386209 | ENSP00000391594 | Olfactory receptor 2A2; Odorant receptor; Olfactory receptors, family 2 | Endogenous retrovirus group 3 member 1 Env polyprotein; Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its fusogenic properties. It can inhibit cell growth through decrease expression of cyclin B1 and increased expression of p21 in vitro; Envelope ERV derived genes | 0.441 |
OR2A2 | NCKIPSD | ENSP00000386209 | ENSP00000294129 | Olfactory receptor 2A2; Odorant receptor; Olfactory receptors, family 2 | NCK-interacting protein with SH3 domain; Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1). Induces microspike formation, in vivo (By similarity). In vitro, stimulates N-WASP- induced ARP2/3 complex activation in the absence of CDC42 (By similarity). May play an important role in the maintenance of sarcomeres and/or in the assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion. Plays a role in angiogenesis | 0.448 |