• Version:
  • 11.0 [archived version]
STRINGSTRING
ZNF385D ZNF385D CLEC2L CLEC2L FAM19A1 FAM19A1 DENND2A DENND2A FAM171B FAM171B TMEM179 TMEM179 TMEM88B TMEM88B TMEM145 TMEM145 FAM189A1 FAM189A1 AMER3 AMER3 TMEM130 TMEM130
"FAM19A1" - Protein FAM19A1 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM19A1Protein FAM19A1; Family with sequence similarity 19 member A1, C-C motif chemokine like (133 aa)    
Predicted Functional Partners:
ZNF385D
Zinc finger protein 385D (395 aa)
     
   
  0.763
DENND2A
DENN domain-containing protein 2A; Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP- bound form. May play a role in late endosomes back to trans-Golgi network/TGN transport; DENN/MADD domain containing (1009 aa)
           
  0.712
CLEC2L
C-type lectin domain family 2 member L (214 aa)
     
   
  0.674
TMEM179
Transmembrane protein 179; Belongs to the TMEM179 family (233 aa)
     
   
  0.651
TMEM130
Transmembrane protein 130 (435 aa)
     
   
  0.640
TMEM88B
Transmembrane protein 88B (163 aa)
     
   
  0.630
AMER3
APC membrane recruitment protein 3; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity) (861 aa)
     
   
  0.622
FAM171B
Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family (826 aa)
     
   
  0.622
TMEM145
Transmembrane protein 145 (493 aa)
     
   
  0.611
FAM189A1
Protein FAM189A1; Family with sequence similarity 189 member A1; Belongs to the FAM189 family (539 aa)
     
   
  0.608
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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