• Version:
  • 11.0 [archived version]
STRINGSTRING
FRG2C FRG2C FAM104B FAM104B UBTFL1 UBTFL1 OR4C3 OR4C3 CDCP2 CDCP2 ZNF717 ZNF717 TRIM28 TRIM28 HNRNPCP5 HNRNPCP5 OR8U1 OR8U1 OR5M11 OR5M11 HNRNPCL2 HNRNPCL2
"ZNF717" - Zinc finger protein 717 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF717Zinc finger protein 717; Zinc fingers C2H2-type (110 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
     
    0.903
OR4C3
Olfactory receptor 4C3; Odorant receptor; Olfactory receptors, family 4 (329 aa)
           
  0.668
FRG2C
Protein FRG2-like-2; FSHD region gene 2 family member C (282 aa)
           
  0.648
OR8U1
Olfactory receptor 8U1; Odorant receptor; Olfactory receptors, family 8 (309 aa)
           
  0.587
HNRNPCL2
Heterogeneous nuclear ribonucleoprotein C-like 3; May play a role in nucleosome assembly by neutralizing basic proteins such as A and B core hnRNPs (293 aa)
       
 
  0.579
FAM104B
Family with sequence similarity 104 member B (116 aa)
           
  0.556
HNRNPCP5
Heterogeneous nuclear ribonucleoprotein C-like 2; May play a role in nucleosome assembly by neutralizing basic proteins such as A and B core hnRNPs (293 aa)
       
 
  0.525
CDCP2
CUB domain containing protein 2 (449 aa)
           
  0.493
OR5M11
Olfactory receptor 5M11; Odorant receptor; Olfactory receptors, family 5 (305 aa)
           
  0.479
UBTFL1
Upstream-binding factor 1-like protein 1; Essential for proliferation of the inner cell mass and trophectodermal cells in peri-implantation development (393 aa)
       
 
  0.478
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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