| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BCL2L15 | C3orf14 | ENSP00000376992 | ENSP00000418086 | Bcl-2-like protein 15; BCL2 like 15 | Uncharacterized protein C3orf14; Chromosome 3 open reading frame 14 | 0.541 |
| BCL2L15 | CCSAP | ENSP00000376992 | ENSP00000284617 | Bcl-2-like protein 15; BCL2 like 15 | Centriole, cilia and spindle-associated protein; Plays a role in microtubule (MT) stabilization and this stabilization involves the maintenance of NUMA1 at the spindle poles. Colocalizes with polyglutamylated MTs to promote MT stabilization and regulate bipolar spindle formation in mitosis. Binding of CCSAP to centrosomes and the spindle around centrosomes during mitosis inhibits MT depolymerization, thereby stabilizing the mitotic spindle. May play a role in embryonic development. May be required for proper cilia beating (By similarity) | 0.484 |
| BCL2L15 | FAM105A | ENSP00000376992 | ENSP00000274217 | Bcl-2-like protein 15; BCL2 like 15 | Inactive ubiquitin thioesterase FAM105A; Family with sequence similarity 105 member A; Belongs to the peptidase C65 family. Otulin subfamily | 0.483 |
| BCL2L15 | LSMEM1 | ENSP00000376992 | ENSP00000323304 | Bcl-2-like protein 15; BCL2 like 15 | Leucine rich single-pass membrane protein 1 | 0.521 |
| BCL2L15 | MRPL50 | ENSP00000376992 | ENSP00000363999 | Bcl-2-like protein 15; BCL2 like 15 | Mitochondrial ribosomal protein L50 | 0.541 |
| BCL2L15 | RNF34 | ENSP00000376992 | ENSP00000376258 | Bcl-2-like protein 15; BCL2 like 15 | E3 ubiquitin-protein ligase RNF34; E3 ubiquitin-protein ligase that regulates several biological processes through the ubiquitin-mediated proteasomal degradation of various target proteins. Ubiquitinates the caspases CASP8 and CASP10, promoting their proteasomal degradation, to negatively regulate cell death downstream of death domain receptors in the extrinsic pathway of apoptosis. May mediate ’Lys-48’-linked polyubiquitination of RIPK1 and its subsequent proteasomal degradation thereby indirectly regulating the tumor necrosis factor-mediated signaling pathway (Ref.13). Negatively reg [...] | 0.509 |
| BCL2L15 | ZPBP2 | ENSP00000376992 | ENSP00000335384 | Bcl-2-like protein 15; BCL2 like 15 | Zona pellucida-binding protein 2; Is implicated in sperm-oocyte interaction during fertilization; Immunoglobulin like domain containing | 0.510 |
| C3orf14 | BCL2L15 | ENSP00000418086 | ENSP00000376992 | Uncharacterized protein C3orf14; Chromosome 3 open reading frame 14 | Bcl-2-like protein 15; BCL2 like 15 | 0.541 |
| C3orf14 | CCSAP | ENSP00000418086 | ENSP00000284617 | Uncharacterized protein C3orf14; Chromosome 3 open reading frame 14 | Centriole, cilia and spindle-associated protein; Plays a role in microtubule (MT) stabilization and this stabilization involves the maintenance of NUMA1 at the spindle poles. Colocalizes with polyglutamylated MTs to promote MT stabilization and regulate bipolar spindle formation in mitosis. Binding of CCSAP to centrosomes and the spindle around centrosomes during mitosis inhibits MT depolymerization, thereby stabilizing the mitotic spindle. May play a role in embryonic development. May be required for proper cilia beating (By similarity) | 0.562 |
| C3orf14 | FAM105A | ENSP00000418086 | ENSP00000274217 | Uncharacterized protein C3orf14; Chromosome 3 open reading frame 14 | Inactive ubiquitin thioesterase FAM105A; Family with sequence similarity 105 member A; Belongs to the peptidase C65 family. Otulin subfamily | 0.560 |
| C3orf14 | LSMEM1 | ENSP00000418086 | ENSP00000323304 | Uncharacterized protein C3orf14; Chromosome 3 open reading frame 14 | Leucine rich single-pass membrane protein 1 | 0.636 |
| C3orf14 | MRPL50 | ENSP00000418086 | ENSP00000363999 | Uncharacterized protein C3orf14; Chromosome 3 open reading frame 14 | Mitochondrial ribosomal protein L50 | 0.621 |
| C3orf14 | OR13A1 | ENSP00000418086 | ENSP00000451950 | Uncharacterized protein C3orf14; Chromosome 3 open reading frame 14 | Olfactory receptor 13A1; Odorant receptor; Olfactory receptors, family 13 | 0.578 |
| C3orf14 | RNF34 | ENSP00000418086 | ENSP00000376258 | Uncharacterized protein C3orf14; Chromosome 3 open reading frame 14 | E3 ubiquitin-protein ligase RNF34; E3 ubiquitin-protein ligase that regulates several biological processes through the ubiquitin-mediated proteasomal degradation of various target proteins. Ubiquitinates the caspases CASP8 and CASP10, promoting their proteasomal degradation, to negatively regulate cell death downstream of death domain receptors in the extrinsic pathway of apoptosis. May mediate ’Lys-48’-linked polyubiquitination of RIPK1 and its subsequent proteasomal degradation thereby indirectly regulating the tumor necrosis factor-mediated signaling pathway (Ref.13). Negatively reg [...] | 0.568 |
| C3orf14 | SATL1 | ENSP00000418086 | ENSP00000425421 | Uncharacterized protein C3orf14; Chromosome 3 open reading frame 14 | Spermidine/spermine N1-acetyl transferase like 1; GCN5 related N-acetyltransferases | 0.645 |
| C3orf14 | TMPRSS3 | ENSP00000418086 | ENSP00000291532 | Uncharacterized protein C3orf14; Chromosome 3 open reading frame 14 | Transmembrane protease serine 3; Probable serine protease that plays a role in hearing. Acts as a permissive factor for cochlear hair cell survival and activation at the onset of hearing and is required for saccular hair cell survival (By similarity). Activates ENaC (in vitro); Belongs to the peptidase S1 family | 0.647 |
| C3orf14 | ZPBP2 | ENSP00000418086 | ENSP00000335384 | Uncharacterized protein C3orf14; Chromosome 3 open reading frame 14 | Zona pellucida-binding protein 2; Is implicated in sperm-oocyte interaction during fertilization; Immunoglobulin like domain containing | 0.588 |
| CCSAP | BCL2L15 | ENSP00000284617 | ENSP00000376992 | Centriole, cilia and spindle-associated protein; Plays a role in microtubule (MT) stabilization and this stabilization involves the maintenance of NUMA1 at the spindle poles. Colocalizes with polyglutamylated MTs to promote MT stabilization and regulate bipolar spindle formation in mitosis. Binding of CCSAP to centrosomes and the spindle around centrosomes during mitosis inhibits MT depolymerization, thereby stabilizing the mitotic spindle. May play a role in embryonic development. May be required for proper cilia beating (By similarity) | Bcl-2-like protein 15; BCL2 like 15 | 0.484 |
| CCSAP | C3orf14 | ENSP00000284617 | ENSP00000418086 | Centriole, cilia and spindle-associated protein; Plays a role in microtubule (MT) stabilization and this stabilization involves the maintenance of NUMA1 at the spindle poles. Colocalizes with polyglutamylated MTs to promote MT stabilization and regulate bipolar spindle formation in mitosis. Binding of CCSAP to centrosomes and the spindle around centrosomes during mitosis inhibits MT depolymerization, thereby stabilizing the mitotic spindle. May play a role in embryonic development. May be required for proper cilia beating (By similarity) | Uncharacterized protein C3orf14; Chromosome 3 open reading frame 14 | 0.562 |
| CCSAP | FAM105A | ENSP00000284617 | ENSP00000274217 | Centriole, cilia and spindle-associated protein; Plays a role in microtubule (MT) stabilization and this stabilization involves the maintenance of NUMA1 at the spindle poles. Colocalizes with polyglutamylated MTs to promote MT stabilization and regulate bipolar spindle formation in mitosis. Binding of CCSAP to centrosomes and the spindle around centrosomes during mitosis inhibits MT depolymerization, thereby stabilizing the mitotic spindle. May play a role in embryonic development. May be required for proper cilia beating (By similarity) | Inactive ubiquitin thioesterase FAM105A; Family with sequence similarity 105 member A; Belongs to the peptidase C65 family. Otulin subfamily | 0.508 |
