node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SCRN1 | SLC35A5 | ENSP00000388942 | ENSP00000417654 | Secernin-1; Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium (By similarity) | Probable UDP-sugar transporter protein SLC35A5; Solute carrier family 35 member A5 | 0.717 |
SLC35A5 | SCRN1 | ENSP00000417654 | ENSP00000388942 | Probable UDP-sugar transporter protein SLC35A5; Solute carrier family 35 member A5 | Secernin-1; Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium (By similarity) | 0.717 |
SLC35A5 | SLC35B1 | ENSP00000417654 | ENSP00000240333 | Probable UDP-sugar transporter protein SLC35A5; Solute carrier family 35 member A5 | Solute carrier family 35 member B1; Probable sugar transporter; Belongs to the nucleotide-sugar transporter family. SLC35B subfamily | 0.680 |
SLC35A5 | SLC35B3 | ENSP00000417654 | ENSP00000368981 | Probable UDP-sugar transporter protein SLC35A5; Solute carrier family 35 member A5 | Adenosine 3’-phospho 5’-phosphosulfate transporter 2; Mediates the transport of adenosine 3’-phospho 5’- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon; Solute carriers | 0.672 |
SLC35A5 | SLC35B4 | ENSP00000417654 | ENSP00000367770 | Probable UDP-sugar transporter protein SLC35A5; Solute carrier family 35 member A5 | UDP-xylose and UDP-N-acetylglucosamine transporter; Sugar transporter that specifically mediates the transport of UDP-xylose (UDP-Xyl) and UDP-N-acetylglucosamine (UDP-GlcNAc) from cytosol into Golgi; Belongs to the nucleotide-sugar transporter family. SLC35B subfamily | 0.573 |
SLC35A5 | SLC35C1 | ENSP00000417654 | ENSP00000313318 | Probable UDP-sugar transporter protein SLC35A5; Solute carrier family 35 member A5 | GDP-fucose transporter 1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen; Belongs to the TPT transporter family. SLC35C subfamily | 0.710 |
SLC35A5 | SLC35C2 | ENSP00000417654 | ENSP00000318960 | Probable UDP-sugar transporter protein SLC35A5; Solute carrier family 35 member A5 | Solute carrier family 35 member C2; May play an important role in the cellular response to tissue hypoxia. May be either a GDP-fucose transporter that competes with SLC35C1 for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells; Solute carriers | 0.627 |
SLC35A5 | SLC35D1 | ENSP00000417654 | ENSP00000235345 | Probable UDP-sugar transporter protein SLC35A5; Solute carrier family 35 member A5 | UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter; Transports both UDP-glucuronic acid (UDP-GlcA) and UDP- N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm into the endoplasmic reticulum lumen. Plays a role in chondroitin sulfate biosynthesis, which is important for formation of cartilage extracellular matrix and normal skeletal development (By similarity); Solute carriers | 0.628 |
SLC35A5 | SLC35D2 | ENSP00000417654 | ENSP00000253270 | Probable UDP-sugar transporter protein SLC35A5; Solute carrier family 35 member A5 | UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter; Antiporter transporting nucleotide sugars such as UDP-N- acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP- mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling; Solute carriers | 0.602 |
SLC35A5 | SLC35D3 | ENSP00000417654 | ENSP00000333591 | Probable UDP-sugar transporter protein SLC35A5; Solute carrier family 35 member A5 | Solute carrier family 35 member D3; May play a role in hemostasis as a regulator of the biosynthesis of platelet-dense granules; Solute carriers | 0.649 |
SLC35A5 | SPATA21 | ENSP00000417654 | ENSP00000335612 | Probable UDP-sugar transporter protein SLC35A5; Solute carrier family 35 member A5 | Spermatogenesis-associated protein 21; Involved in the differentiation of haploid spermatids; EF-hand domain containing | 0.557 |
SLC35B1 | SLC35A5 | ENSP00000240333 | ENSP00000417654 | Solute carrier family 35 member B1; Probable sugar transporter; Belongs to the nucleotide-sugar transporter family. SLC35B subfamily | Probable UDP-sugar transporter protein SLC35A5; Solute carrier family 35 member A5 | 0.680 |
SLC35B1 | SLC35C1 | ENSP00000240333 | ENSP00000313318 | Solute carrier family 35 member B1; Probable sugar transporter; Belongs to the nucleotide-sugar transporter family. SLC35B subfamily | GDP-fucose transporter 1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen; Belongs to the TPT transporter family. SLC35C subfamily | 0.793 |
SLC35B1 | SLC35C2 | ENSP00000240333 | ENSP00000318960 | Solute carrier family 35 member B1; Probable sugar transporter; Belongs to the nucleotide-sugar transporter family. SLC35B subfamily | Solute carrier family 35 member C2; May play an important role in the cellular response to tissue hypoxia. May be either a GDP-fucose transporter that competes with SLC35C1 for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells; Solute carriers | 0.595 |
SLC35B1 | SLC35D1 | ENSP00000240333 | ENSP00000235345 | Solute carrier family 35 member B1; Probable sugar transporter; Belongs to the nucleotide-sugar transporter family. SLC35B subfamily | UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter; Transports both UDP-glucuronic acid (UDP-GlcA) and UDP- N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm into the endoplasmic reticulum lumen. Plays a role in chondroitin sulfate biosynthesis, which is important for formation of cartilage extracellular matrix and normal skeletal development (By similarity); Solute carriers | 0.912 |
SLC35B1 | SLC35D2 | ENSP00000240333 | ENSP00000253270 | Solute carrier family 35 member B1; Probable sugar transporter; Belongs to the nucleotide-sugar transporter family. SLC35B subfamily | UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter; Antiporter transporting nucleotide sugars such as UDP-N- acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP- mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling; Solute carriers | 0.562 |
SLC35B1 | SLC35D3 | ENSP00000240333 | ENSP00000333591 | Solute carrier family 35 member B1; Probable sugar transporter; Belongs to the nucleotide-sugar transporter family. SLC35B subfamily | Solute carrier family 35 member D3; May play a role in hemostasis as a regulator of the biosynthesis of platelet-dense granules; Solute carriers | 0.573 |
SLC35B3 | SLC35A5 | ENSP00000368981 | ENSP00000417654 | Adenosine 3’-phospho 5’-phosphosulfate transporter 2; Mediates the transport of adenosine 3’-phospho 5’- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon; Solute carriers | Probable UDP-sugar transporter protein SLC35A5; Solute carrier family 35 member A5 | 0.672 |
SLC35B3 | SLC35C1 | ENSP00000368981 | ENSP00000313318 | Adenosine 3’-phospho 5’-phosphosulfate transporter 2; Mediates the transport of adenosine 3’-phospho 5’- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon; Solute carriers | GDP-fucose transporter 1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen; Belongs to the TPT transporter family. SLC35C subfamily | 0.807 |
SLC35B3 | SLC35C2 | ENSP00000368981 | ENSP00000318960 | Adenosine 3’-phospho 5’-phosphosulfate transporter 2; Mediates the transport of adenosine 3’-phospho 5’- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon; Solute carriers | Solute carrier family 35 member C2; May play an important role in the cellular response to tissue hypoxia. May be either a GDP-fucose transporter that competes with SLC35C1 for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells; Solute carriers | 0.832 |