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  • 11.0 [archived version]
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THTPA THTPA TRIM28 TRIM28 TBPL1 TBPL1 ERLEC1 ERLEC1 ZNF786 ZNF786 NDUFAF3 NDUFAF3 CAMKMT CAMKMT METTL22 METTL22 COQ10B COQ10B HMBOX1 HMBOX1 EEF1E1 EEF1E1
"ZNF786" - Zinc finger protein 786 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZNF786Zinc finger protein 786; May be involved in transcriptional regulation; Zinc fingers C2H2-type (782 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
     
    0.903
COQ10B
Coenzyme Q-binding protein COQ10 homolog B, mitochondrial; Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes (By similarity); Belongs to the COQ10 family (238 aa)
     
 
  0.731
EEF1E1
Eukaryotic translation elongation factor 1 epsilon-1; Positive modulator of ATM response to DNA damage (174 aa)
       
 
  0.641
CAMKMT
Calmodulin-lysine N-methyltransferase; Catalyzes the trimethylation of ’Lys-116’ in calmodulin; Seven-beta-strand methyltransferase motif containing (323 aa)
           
  0.593
TBPL1
TATA box-binding protein-like protein 1; Part of a specialized transcription system that mediates the transcription of most ribosomal proteins through the 5’-TCT-3’ motif which is a core promoter element at these genes. Seems to also mediate the transcription of NF1. Does not bind the TATA box (186 aa)
       
 
  0.558
HMBOX1
Homeobox-containing protein 1; Transcription factor. Isoform 1 acts as a transcriptional repressor. Isoform 4 has very low activity as a transcriptional repressor; HNF class homeoboxes (420 aa)
           
  0.551
NDUFAF3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3; Essential factor for the assembly of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I) (184 aa)
           
  0.541
ERLEC1
Endoplasmic reticulum lectin 1; Probable lectin that binds selectively to improperly folded lumenal proteins. May function in endoplasmic reticulum quality control and endoplasmic reticulum-associated degradation (ERAD) of both non-glycosylated proteins and glycoproteins; MRH domain containing (483 aa)
           
  0.540
METTL22
Methyltransferase-like protein 22; Protein N-lysine methyltransferase. In vitro methylates KIN; Belongs to the methyltransferase superfamily. METTL22 family (404 aa)
           
  0.536
THTPA
Thiamine-triphosphatase; Hydrolase highly specific for thiamine triphosphate (ThTP); Belongs to the ThTPase family (230 aa)
           
  0.526
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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