node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGT | CPB1 | ENSP00000355627 | ENSP00000417222 | Angiotensinogen; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis; Endogenous ligands | M14 carboxypeptidases; Belongs to the peptidase M14 family | 0.919 |
CEL | CELA2A | ENSP00000361151 | ENSP00000352639 | Bile salt-activated lipase; Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides; Belongs to the type-B carboxylesterase/lipase family | Chymotrypsin-like elastase family member 2A; Acts upon elastin | 0.651 |
CEL | CELA2B | ENSP00000361151 | ENSP00000365075 | Bile salt-activated lipase; Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides; Belongs to the type-B carboxylesterase/lipase family | Chymotrypsin-like elastase family member 2B; Acts upon elastin; Belongs to the peptidase S1 family. Elastase subfamily | 0.592 |
CEL | CELA3A | ENSP00000361151 | ENSP00000290122 | Bile salt-activated lipase; Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides; Belongs to the type-B carboxylesterase/lipase family | Chymotrypsin-like elastase family member 3A; Efficient protease with alanine specificity but only little elastolytic activity | 0.765 |
CEL | CELA3B | ENSP00000361151 | ENSP00000338369 | Bile salt-activated lipase; Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides; Belongs to the type-B carboxylesterase/lipase family | Chymotrypsin-like elastase family member 3B; Efficient protease with alanine specificity but only little elastolytic activity | 0.882 |
CEL | CPA1 | ENSP00000361151 | ENSP00000011292 | Bile salt-activated lipase; Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides; Belongs to the type-B carboxylesterase/lipase family | Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C- terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro; Belongs to the peptidase M14 family | 0.919 |
CEL | CPB1 | ENSP00000361151 | ENSP00000417222 | Bile salt-activated lipase; Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides; Belongs to the type-B carboxylesterase/lipase family | M14 carboxypeptidases; Belongs to the peptidase M14 family | 0.846 |
CEL | CTRC | ENSP00000361151 | ENSP00000365116 | Bile salt-activated lipase; Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides; Belongs to the type-B carboxylesterase/lipase family | Chymotrypsin-C; Regulates activation and degradation of trypsinogens and procarboxypeptidases by targeting specific cleavage sites within their zymogen precursors. Has chymotrypsin-type protease activity and hypocalcemic activity | 0.612 |
CEL | CTRL | ENSP00000361151 | ENSP00000458537 | Bile salt-activated lipase; Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides; Belongs to the type-B carboxylesterase/lipase family | Chymotrypsin-like protease CTRL-1; Chymotrypsin like; Belongs to the peptidase S1 family | 0.921 |
CEL | PNLIP | ENSP00000361151 | ENSP00000358223 | Bile salt-activated lipase; Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides; Belongs to the type-B carboxylesterase/lipase family | Pancreatic lipase; Belongs to the AB hydrolase superfamily. Lipase family | 0.960 |
CELA2A | CEL | ENSP00000352639 | ENSP00000361151 | Chymotrypsin-like elastase family member 2A; Acts upon elastin | Bile salt-activated lipase; Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides; Belongs to the type-B carboxylesterase/lipase family | 0.651 |
CELA2A | CPA1 | ENSP00000352639 | ENSP00000011292 | Chymotrypsin-like elastase family member 2A; Acts upon elastin | Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C- terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro; Belongs to the peptidase M14 family | 0.871 |
CELA2A | CPB1 | ENSP00000352639 | ENSP00000417222 | Chymotrypsin-like elastase family member 2A; Acts upon elastin | M14 carboxypeptidases; Belongs to the peptidase M14 family | 0.945 |
CELA2A | CTRC | ENSP00000352639 | ENSP00000365116 | Chymotrypsin-like elastase family member 2A; Acts upon elastin | Chymotrypsin-C; Regulates activation and degradation of trypsinogens and procarboxypeptidases by targeting specific cleavage sites within their zymogen precursors. Has chymotrypsin-type protease activity and hypocalcemic activity | 0.473 |
CELA2A | CTRL | ENSP00000352639 | ENSP00000458537 | Chymotrypsin-like elastase family member 2A; Acts upon elastin | Chymotrypsin-like protease CTRL-1; Chymotrypsin like; Belongs to the peptidase S1 family | 0.839 |
CELA2A | PNLIP | ENSP00000352639 | ENSP00000358223 | Chymotrypsin-like elastase family member 2A; Acts upon elastin | Pancreatic lipase; Belongs to the AB hydrolase superfamily. Lipase family | 0.563 |
CELA2B | CEL | ENSP00000365075 | ENSP00000361151 | Chymotrypsin-like elastase family member 2B; Acts upon elastin; Belongs to the peptidase S1 family. Elastase subfamily | Bile salt-activated lipase; Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides; Belongs to the type-B carboxylesterase/lipase family | 0.592 |
CELA2B | CPA1 | ENSP00000365075 | ENSP00000011292 | Chymotrypsin-like elastase family member 2B; Acts upon elastin; Belongs to the peptidase S1 family. Elastase subfamily | Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C- terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro; Belongs to the peptidase M14 family | 0.796 |
CELA2B | CPB1 | ENSP00000365075 | ENSP00000417222 | Chymotrypsin-like elastase family member 2B; Acts upon elastin; Belongs to the peptidase S1 family. Elastase subfamily | M14 carboxypeptidases; Belongs to the peptidase M14 family | 0.878 |
CELA2B | CTRC | ENSP00000365075 | ENSP00000365116 | Chymotrypsin-like elastase family member 2B; Acts upon elastin; Belongs to the peptidase S1 family. Elastase subfamily | Chymotrypsin-C; Regulates activation and degradation of trypsinogens and procarboxypeptidases by targeting specific cleavage sites within their zymogen precursors. Has chymotrypsin-type protease activity and hypocalcemic activity | 0.455 |