node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATP13A3 | ATP1B4 | ENSP00000416508 | ENSP00000218008 | Probable cation-transporting ATPase 13A3; ATPase orphan transporters | Protein ATP1B4; May act as a transcriptional coregulator during muscle development through its interaction with SNW1. Has lost its ancestral function as a Na,K-ATPase beta-subunit; Belongs to the X(+)/potassium ATPases subunit beta family | 0.684 |
ATP13A3 | ATP7A | ENSP00000416508 | ENSP00000345728 | Probable cation-transporting ATPase 13A3; ATPase orphan transporters | Copper-transporting ATPase 1; May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells; ATPase copper transporting | 0.688 |
ATP13A3 | ATP7B | ENSP00000416508 | ENSP00000242839 | Probable cation-transporting ATPase 13A3; ATPase orphan transporters | Copper-transporting ATPase 2; Copper ion transmembrane transporter involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile; ATPase copper transporting | 0.703 |
ATP13A3 | C3orf20 | ENSP00000416508 | ENSP00000253697 | Probable cation-transporting ATPase 13A3; ATPase orphan transporters | Uncharacterized protein C3orf20; Chromosome 3 open reading frame 20 | 0.510 |
ATP13A3 | MBTD1 | ENSP00000416508 | ENSP00000468304 | Probable cation-transporting ATPase 13A3; ATPase orphan transporters | MBT domain-containing protein 1; Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility (By similarity). Specifically binds to monomethylated and dimethylated ’Lys-20’ on histone H4; MBT domain containing | 0.526 |
ATP13A3 | PRRT3 | ENSP00000416508 | ENSP00000392511 | Probable cation-transporting ATPase 13A3; ATPase orphan transporters | Proline rich transmembrane protein 3 | 0.605 |
ATP13A3 | SLC13A1 | ENSP00000416508 | ENSP00000194130 | Probable cation-transporting ATPase 13A3; ATPase orphan transporters | Solute carrier family 13 member 1; Sodium/sulfate cotransporter that mediates sulfate reabsorption in the kidney; Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily | 0.595 |
ATP13A3 | SLC35F1 | ENSP00000416508 | ENSP00000353557 | Probable cation-transporting ATPase 13A3; ATPase orphan transporters | Solute carrier family 35 member F1; Putative solute transporter | 0.579 |
ATP13A3 | XXYLT1 | ENSP00000416508 | ENSP00000309640 | Probable cation-transporting ATPase 13A3; ATPase orphan transporters | Xyloside xylosyltransferase 1; Alpha-1,3-xylosyltransferase, which elongates the O- linked xylose-glucose disaccharide attached to EGF-like repeats in the extracellular domain of target proteins by catalyzing the addition of the second xylose. Known targets include Notch proteins and coagulation factors, such as F9; Glycosyltransferase family 8 | 0.551 |
ATP13A3 | ZNF618 | ENSP00000416508 | ENSP00000288466 | Probable cation-transporting ATPase 13A3; ATPase orphan transporters | Zinc finger protein 618; Zinc fingers C2H2-type | 0.527 |
ATP1B4 | ATP13A3 | ENSP00000218008 | ENSP00000416508 | Protein ATP1B4; May act as a transcriptional coregulator during muscle development through its interaction with SNW1. Has lost its ancestral function as a Na,K-ATPase beta-subunit; Belongs to the X(+)/potassium ATPases subunit beta family | Probable cation-transporting ATPase 13A3; ATPase orphan transporters | 0.684 |
ATP7A | ATP13A3 | ENSP00000345728 | ENSP00000416508 | Copper-transporting ATPase 1; May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells; ATPase copper transporting | Probable cation-transporting ATPase 13A3; ATPase orphan transporters | 0.688 |
ATP7A | ATP7B | ENSP00000345728 | ENSP00000242839 | Copper-transporting ATPase 1; May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells; ATPase copper transporting | Copper-transporting ATPase 2; Copper ion transmembrane transporter involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile; ATPase copper transporting | 0.811 |
ATP7B | ATP13A3 | ENSP00000242839 | ENSP00000416508 | Copper-transporting ATPase 2; Copper ion transmembrane transporter involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile; ATPase copper transporting | Probable cation-transporting ATPase 13A3; ATPase orphan transporters | 0.703 |
ATP7B | ATP7A | ENSP00000242839 | ENSP00000345728 | Copper-transporting ATPase 2; Copper ion transmembrane transporter involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile; ATPase copper transporting | Copper-transporting ATPase 1; May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells; ATPase copper transporting | 0.811 |
C3orf20 | ATP13A3 | ENSP00000253697 | ENSP00000416508 | Uncharacterized protein C3orf20; Chromosome 3 open reading frame 20 | Probable cation-transporting ATPase 13A3; ATPase orphan transporters | 0.510 |
MBTD1 | ATP13A3 | ENSP00000468304 | ENSP00000416508 | MBT domain-containing protein 1; Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility (By similarity). Specifically binds to monomethylated and dimethylated ’Lys-20’ on histone H4; MBT domain containing | Probable cation-transporting ATPase 13A3; ATPase orphan transporters | 0.526 |
MBTD1 | ZNF618 | ENSP00000468304 | ENSP00000288466 | MBT domain-containing protein 1; Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility (By similarity). Specifically binds to monomethylated and dimethylated ’Lys-20’ on histone H4; MBT domain containing | Zinc finger protein 618; Zinc fingers C2H2-type | 0.579 |
PRRT3 | ATP13A3 | ENSP00000392511 | ENSP00000416508 | Proline rich transmembrane protein 3 | Probable cation-transporting ATPase 13A3; ATPase orphan transporters | 0.605 |
SLC13A1 | ATP13A3 | ENSP00000194130 | ENSP00000416508 | Solute carrier family 13 member 1; Sodium/sulfate cotransporter that mediates sulfate reabsorption in the kidney; Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily | Probable cation-transporting ATPase 13A3; ATPase orphan transporters | 0.595 |