node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RPL11 | RPL12 | ENSP00000363676 | ENSP00000354739 | 60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl- transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome throug [...] | 60S ribosomal protein L12; Binds directly to 26S ribosomal RNA | 0.999 |
RPL11 | RPL13A | ENSP00000363676 | ENSP00000375730 | 60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl- transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome throug [...] | 60S ribosomal protein L13a; Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3’-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppre [...] | 0.999 |
RPL11 | RPL19 | ENSP00000363676 | ENSP00000225430 | 60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl- transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome throug [...] | Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family | 0.999 |
RPL11 | RPL32 | ENSP00000363676 | ENSP00000416429 | 60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl- transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome throug [...] | Ribosomal protein L32; Belongs to the eukaryotic ribosomal protein eL32 family | 0.999 |
RPL11 | RPL34 | ENSP00000363676 | ENSP00000378163 | 60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl- transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome throug [...] | 60S ribosomal protein L34; Component of the large ribosomal subunit | 0.999 |
RPL11 | RPL35A | ENSP00000363676 | ENSP00000419117 | 60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl- transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome throug [...] | 60S ribosomal protein L35a; Required for the proliferation and viability of hematopoietic cells. Plays a role in 60S ribosomal subunit formation. The protein was found to bind to both initiator and elongator tRNAs and consequently was assigned to the P site or P and A site | 0.999 |
RPL11 | RPS11 | ENSP00000363676 | ENSP00000270625 | 60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl- transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome throug [...] | Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family | 0.999 |
RPL11 | RPS16 | ENSP00000363676 | ENSP00000251453 | 60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl- transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome throug [...] | Ribosomal protein S16 | 0.999 |
RPL11 | RPS6 | ENSP00000363676 | ENSP00000369757 | 60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl- transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome throug [...] | 40S ribosomal protein S6; May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA; S ribosomal proteins | 0.999 |
RPL11 | RPS8 | ENSP00000363676 | ENSP00000379888 | 60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl- transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome throug [...] | Ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family | 0.999 |
RPL12 | RPL11 | ENSP00000354739 | ENSP00000363676 | 60S ribosomal protein L12; Binds directly to 26S ribosomal RNA | 60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl- transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome throug [...] | 0.999 |
RPL12 | RPL13A | ENSP00000354739 | ENSP00000375730 | 60S ribosomal protein L12; Binds directly to 26S ribosomal RNA | 60S ribosomal protein L13a; Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3’-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppre [...] | 0.999 |
RPL12 | RPL19 | ENSP00000354739 | ENSP00000225430 | 60S ribosomal protein L12; Binds directly to 26S ribosomal RNA | Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family | 0.999 |
RPL12 | RPL32 | ENSP00000354739 | ENSP00000416429 | 60S ribosomal protein L12; Binds directly to 26S ribosomal RNA | Ribosomal protein L32; Belongs to the eukaryotic ribosomal protein eL32 family | 0.999 |
RPL12 | RPL34 | ENSP00000354739 | ENSP00000378163 | 60S ribosomal protein L12; Binds directly to 26S ribosomal RNA | 60S ribosomal protein L34; Component of the large ribosomal subunit | 0.999 |
RPL12 | RPL35A | ENSP00000354739 | ENSP00000419117 | 60S ribosomal protein L12; Binds directly to 26S ribosomal RNA | 60S ribosomal protein L35a; Required for the proliferation and viability of hematopoietic cells. Plays a role in 60S ribosomal subunit formation. The protein was found to bind to both initiator and elongator tRNAs and consequently was assigned to the P site or P and A site | 0.999 |
RPL12 | RPS11 | ENSP00000354739 | ENSP00000270625 | 60S ribosomal protein L12; Binds directly to 26S ribosomal RNA | Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family | 0.999 |
RPL12 | RPS16 | ENSP00000354739 | ENSP00000251453 | 60S ribosomal protein L12; Binds directly to 26S ribosomal RNA | Ribosomal protein S16 | 0.999 |
RPL12 | RPS6 | ENSP00000354739 | ENSP00000369757 | 60S ribosomal protein L12; Binds directly to 26S ribosomal RNA | 40S ribosomal protein S6; May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA; S ribosomal proteins | 0.999 |
RPL12 | RPS8 | ENSP00000354739 | ENSP00000379888 | 60S ribosomal protein L12; Binds directly to 26S ribosomal RNA | Ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family | 0.999 |