WDR27 protein (human) - STRING database

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

WDR27

WD repeat-containing protein 27; WD repeat domain containing (895 aa)

Predicted Functional Partners:

PHF10

0.825

BBS10

0.791

TCTE3

0.756

CXorf56

0.718

C6orf120

0.708

LRRC23

0.690

PDXDC1

0.689

FRMD1

0.672

WRB

0.672

FAM120B

0.657

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BBS10	WDR27	ENSP00000376946	ENSP00000416289	Bardet-Biedl syndrome 10 protein; Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation; Belongs to the TCP-1 chaperonin family	WD repeat-containing protein 27; WD repeat domain containing	0.791
C6orf120	FAM120B	ENSP00000346931	ENSP00000440125	UPF0669 protein C6orf120; May be involved in induction of apoptosis in CD4(+) T- cells, but not CD8(+) T-cells or hepatocytes	Constitutive coactivator of peroxisome proliferator-activated receptor gamma; Functions as a transactivator of PPARG and ESR1. Functions in adipogenesis through PPARG activation (By similarity); Belongs to the constitutive coactivator of PPAR-gamma family	0.581
C6orf120	FRMD1	ENSP00000346931	ENSP00000283309	UPF0669 protein C6orf120; May be involved in induction of apoptosis in CD4(+) T- cells, but not CD8(+) T-cells or hepatocytes	FERM domain containing 1	0.489
C6orf120	PHF10	ENSP00000346931	ENSP00000341805	UPF0669 protein C6orf120; May be involved in induction of apoptosis in CD4(+) T- cells, but not CD8(+) T-cells or hepatocytes	PHD finger protein 10; Involved in transcription activity regulation by chromatin remodeling. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors. During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. [...]	0.589
C6orf120	TCTE3	ENSP00000346931	ENSP00000355736	UPF0669 protein C6orf120; May be involved in induction of apoptosis in CD4(+) T- cells, but not CD8(+) T-cells or hepatocytes	Tctex1 domain-containing protein 3; May be an accessory component of axonemal dynein and cytoplasmic dynein 1. Candidate for involvement in male sterility (By similarity); Belongs to the dynein light chain Tctex-type family	0.669
C6orf120	WDR27	ENSP00000346931	ENSP00000416289	UPF0669 protein C6orf120; May be involved in induction of apoptosis in CD4(+) T- cells, but not CD8(+) T-cells or hepatocytes	WD repeat-containing protein 27; WD repeat domain containing	0.708
CXorf56	PDXDC1	ENSP00000441786	ENSP00000379691	UPF0428 protein CXorf56; Chromosome X open reading frame 56; Spliceosomal C complex	Pyridoxal-dependent decarboxylase domain-containing protein 1; Pyridoxal dependent decarboxylase domain containing 1; Belongs to the group II decarboxylase family	0.682
CXorf56	WDR27	ENSP00000441786	ENSP00000416289	UPF0428 protein CXorf56; Chromosome X open reading frame 56; Spliceosomal C complex	WD repeat-containing protein 27; WD repeat domain containing	0.718
CXorf56	WRB	ENSP00000441786	ENSP00000327716	UPF0428 protein CXorf56; Chromosome X open reading frame 56; Spliceosomal C complex	Tail-anchored protein insertion receptor WRB; Receptor for ASNA1/TRC40-mediated insertion of tail- anchored (TA) proteins into the ER membrane; Belongs to the WRB/GET1 family	0.678
FAM120B	C6orf120	ENSP00000440125	ENSP00000346931	Constitutive coactivator of peroxisome proliferator-activated receptor gamma; Functions as a transactivator of PPARG and ESR1. Functions in adipogenesis through PPARG activation (By similarity); Belongs to the constitutive coactivator of PPAR-gamma family	UPF0669 protein C6orf120; May be involved in induction of apoptosis in CD4(+) T- cells, but not CD8(+) T-cells or hepatocytes	0.581
FAM120B	FRMD1	ENSP00000440125	ENSP00000283309	Constitutive coactivator of peroxisome proliferator-activated receptor gamma; Functions as a transactivator of PPARG and ESR1. Functions in adipogenesis through PPARG activation (By similarity); Belongs to the constitutive coactivator of PPAR-gamma family	FERM domain containing 1	0.586
FAM120B	PHF10	ENSP00000440125	ENSP00000341805	Constitutive coactivator of peroxisome proliferator-activated receptor gamma; Functions as a transactivator of PPARG and ESR1. Functions in adipogenesis through PPARG activation (By similarity); Belongs to the constitutive coactivator of PPAR-gamma family	PHD finger protein 10; Involved in transcription activity regulation by chromatin remodeling. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors. During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. [...]	0.609
FAM120B	TCTE3	ENSP00000440125	ENSP00000355736	Constitutive coactivator of peroxisome proliferator-activated receptor gamma; Functions as a transactivator of PPARG and ESR1. Functions in adipogenesis through PPARG activation (By similarity); Belongs to the constitutive coactivator of PPAR-gamma family	Tctex1 domain-containing protein 3; May be an accessory component of axonemal dynein and cytoplasmic dynein 1. Candidate for involvement in male sterility (By similarity); Belongs to the dynein light chain Tctex-type family	0.605
FAM120B	WDR27	ENSP00000440125	ENSP00000416289	Constitutive coactivator of peroxisome proliferator-activated receptor gamma; Functions as a transactivator of PPARG and ESR1. Functions in adipogenesis through PPARG activation (By similarity); Belongs to the constitutive coactivator of PPAR-gamma family	WD repeat-containing protein 27; WD repeat domain containing	0.657
FRMD1	C6orf120	ENSP00000283309	ENSP00000346931	FERM domain containing 1	UPF0669 protein C6orf120; May be involved in induction of apoptosis in CD4(+) T- cells, but not CD8(+) T-cells or hepatocytes	0.489
FRMD1	FAM120B	ENSP00000283309	ENSP00000440125	FERM domain containing 1	Constitutive coactivator of peroxisome proliferator-activated receptor gamma; Functions as a transactivator of PPARG and ESR1. Functions in adipogenesis through PPARG activation (By similarity); Belongs to the constitutive coactivator of PPAR-gamma family	0.586
FRMD1	PHF10	ENSP00000283309	ENSP00000341805	FERM domain containing 1	PHD finger protein 10; Involved in transcription activity regulation by chromatin remodeling. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors. During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. [...]	0.624
FRMD1	TCTE3	ENSP00000283309	ENSP00000355736	FERM domain containing 1	Tctex1 domain-containing protein 3; May be an accessory component of axonemal dynein and cytoplasmic dynein 1. Candidate for involvement in male sterility (By similarity); Belongs to the dynein light chain Tctex-type family	0.617
FRMD1	WDR27	ENSP00000283309	ENSP00000416289	FERM domain containing 1	WD repeat-containing protein 27; WD repeat domain containing	0.672
LRRC23	WDR27	ENSP00000390932	ENSP00000416289	Leucine-rich repeat-containing protein 23; Leucine rich repeat containing 23	WD repeat-containing protein 27; WD repeat domain containing	0.690

page 1 of 3

Network

Fusion

Experiments

Cooccurrence

Textmining

Coexpression

Databases

Neighborhood

© STRING Consortium 2020

Credits

Access

Info

About