node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDK10 | FANCA | ENSP00000338673 | ENSP00000373952 | Cyclin-dependent kinase 10; Cyclin-dependent kinase that phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells) | Fanconi anemia group A protein; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability; Fanconi anemia complementation groups | 0.402 |
CDK10 | GALNS | ENSP00000338673 | ENSP00000268695 | Cyclin-dependent kinase 10; Cyclin-dependent kinase that phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells) | N-acetylgalactosamine-6-sulfatase; Galactosamine-6-sulfatase; Belongs to the sulfatase family | 0.633 |
CDK10 | ZNF276 | ENSP00000338673 | ENSP00000415836 | Cyclin-dependent kinase 10; Cyclin-dependent kinase that phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells) | Zinc finger protein 276; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.738 |
FANCA | CDK10 | ENSP00000373952 | ENSP00000338673 | Fanconi anemia group A protein; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability; Fanconi anemia complementation groups | Cyclin-dependent kinase 10; Cyclin-dependent kinase that phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells) | 0.402 |
FANCA | ZNF276 | ENSP00000373952 | ENSP00000415836 | Fanconi anemia group A protein; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability; Fanconi anemia complementation groups | Zinc finger protein 276; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.640 |
FSBP | NAIF1 | ENSP00000420405 | ENSP00000362170 | Fibrinogen silencer-binding protein; Transcriptional repressor that down-regulates the expression of the fibrinogen gamma chain. Represses transcription of GSK3B gene promoter via its interaction with APBA1 | Nuclear apoptosis-inducing factor 1; Induces apoptosis; Belongs to the NAIF1 family | 0.733 |
FSBP | SRBD1 | ENSP00000420405 | ENSP00000263736 | Fibrinogen silencer-binding protein; Transcriptional repressor that down-regulates the expression of the fibrinogen gamma chain. Represses transcription of GSK3B gene promoter via its interaction with APBA1 | S1 RNA-binding domain-containing protein 1; S1 RNA binding domain 1 | 0.708 |
FSBP | ZNF276 | ENSP00000420405 | ENSP00000415836 | Fibrinogen silencer-binding protein; Transcriptional repressor that down-regulates the expression of the fibrinogen gamma chain. Represses transcription of GSK3B gene promoter via its interaction with APBA1 | Zinc finger protein 276; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.743 |
FSBP | ZNF827 | ENSP00000420405 | ENSP00000368761 | Fibrinogen silencer-binding protein; Transcriptional repressor that down-regulates the expression of the fibrinogen gamma chain. Represses transcription of GSK3B gene promoter via its interaction with APBA1 | Zinc finger protein 827; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.713 |
GALNS | CDK10 | ENSP00000268695 | ENSP00000338673 | N-acetylgalactosamine-6-sulfatase; Galactosamine-6-sulfatase; Belongs to the sulfatase family | Cyclin-dependent kinase 10; Cyclin-dependent kinase that phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells) | 0.633 |
GALNS | ZNF276 | ENSP00000268695 | ENSP00000415836 | N-acetylgalactosamine-6-sulfatase; Galactosamine-6-sulfatase; Belongs to the sulfatase family | Zinc finger protein 276; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.627 |
GAS8 | ZNF276 | ENSP00000268699 | ENSP00000415836 | Growth arrest-specific protein 8; Cytoskeletal linker which binds microtubules and probably functions in axonemal and non-axonemal dynein regulation. May play a role in the spermatozoa motility (By similarity). May play a role in cilia motility; Dynein regulatory complex | Zinc finger protein 276; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.725 |
LRWD1 | ZNF276 | ENSP00000292616 | ENSP00000415836 | Leucine-rich repeat and WD repeat-containing protein 1; Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability; WD repeat d [...] | Zinc finger protein 276; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.636 |
MC1R | ZNF276 | ENSP00000451605 | ENSP00000415836 | Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family | Zinc finger protein 276; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.654 |
NAIF1 | FSBP | ENSP00000362170 | ENSP00000420405 | Nuclear apoptosis-inducing factor 1; Induces apoptosis; Belongs to the NAIF1 family | Fibrinogen silencer-binding protein; Transcriptional repressor that down-regulates the expression of the fibrinogen gamma chain. Represses transcription of GSK3B gene promoter via its interaction with APBA1 | 0.733 |
NAIF1 | SRBD1 | ENSP00000362170 | ENSP00000263736 | Nuclear apoptosis-inducing factor 1; Induces apoptosis; Belongs to the NAIF1 family | S1 RNA-binding domain-containing protein 1; S1 RNA binding domain 1 | 0.693 |
NAIF1 | ZNF276 | ENSP00000362170 | ENSP00000415836 | Nuclear apoptosis-inducing factor 1; Induces apoptosis; Belongs to the NAIF1 family | Zinc finger protein 276; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.703 |
NAIF1 | ZNF827 | ENSP00000362170 | ENSP00000368761 | Nuclear apoptosis-inducing factor 1; Induces apoptosis; Belongs to the NAIF1 family | Zinc finger protein 827; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.760 |
SRBD1 | FSBP | ENSP00000263736 | ENSP00000420405 | S1 RNA-binding domain-containing protein 1; S1 RNA binding domain 1 | Fibrinogen silencer-binding protein; Transcriptional repressor that down-regulates the expression of the fibrinogen gamma chain. Represses transcription of GSK3B gene promoter via its interaction with APBA1 | 0.708 |
SRBD1 | NAIF1 | ENSP00000263736 | ENSP00000362170 | S1 RNA-binding domain-containing protein 1; S1 RNA binding domain 1 | Nuclear apoptosis-inducing factor 1; Induces apoptosis; Belongs to the NAIF1 family | 0.693 |