https://version11.string-db.org/cgi/show_network_section.pl?networkId=yKECtPfLUlyY
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[archived version]
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There are several matches for 'ENSP00000415139'.
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organism
protein
Homo sapiens
TMED7 - Transmembrane emp24 domain-containing protein 7; Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Appears to play a role in the biosynthesis of secreted cargo including processing and post- translational modifications; Transmembrane p24 trafficking proteins
[a.k.a. TMED7-TICAM2, CGI-109, 51014,
ENSP00000415139
]
Homo sapiens
TICAM2 - TIR domain-containing adapter molecule 2; Functions as sorting adapter in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. Physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1; signaling is proposed to occur in early endosomes after endocytosis of TLR4. May also be involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB; however, reports are controversial. Involved in IL-18 signaling and is proposed to function as a sorting adaptor for MYD88 in IL-18 [...]
[a.k.a. TIRAP3, TRAM, TIRP,
ENSP00000415139
]