| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCDC107 | DHX35 | ENSP00000414964 | ENSP00000252011 | Coiled-coil domain containing 107 | Probable ATP-dependent RNA helicase DHX35; May be involved in pre-mRNA splicing; Belongs to the DEAD box helicase family. DEAH subfamily | 0.591 |
| CCDC107 | DXO | ENSP00000414964 | ENSP00000364498 | Coiled-coil domain containing 107 | Decapping and exoribonuclease protein; Ribonuclease that specifically degrades pre-mRNAs with a defective 5’ end cap and is part of a pre-mRNA capping quality control. Has decapping, pyrophosphohydrolase and 5’-3’ exonuclease activities. Has decapping activity toward incomplete 5’ end cap mRNAs such as unmethylated 5’ end-capped RNA to release GpppN and 5’ end monophosphate RNA. The 5’ end monophosphate RNA is then degraded by the 5’-3’ exoribonuclease activity, enabling this enzyme to decap and degrade incompletely capped mRNAs. Also possesses RNA 5’-pyrophosphohydrolase activity by h [...] | 0.672 |
| CCDC107 | FAF1 | ENSP00000414964 | ENSP00000379457 | Coiled-coil domain containing 107 | FAS-associated factor 1; Potentiates but cannot initiate FAS-induced apoptosis; UBX domain containing | 0.511 |
| CCDC107 | GARNL3 | ENSP00000414964 | ENSP00000362485 | Coiled-coil domain containing 107 | GTPase-activating Rap/Ran-GAP domain-like protein 3; GTPase activating Rap/RanGAP domain like 3 | 0.524 |
| CCDC107 | LMNTD1 | ENSP00000414964 | ENSP00000407353 | Coiled-coil domain containing 107 | Lamin tail domain containing 1 | 0.494 |
| CCDC107 | MRGBP | ENSP00000414964 | ENSP00000359518 | Coiled-coil domain containing 107 | MRG/MORF4L-binding protein; Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative [...] | 0.476 |
| CCDC107 | MYO10 | ENSP00000414964 | ENSP00000421280 | Coiled-coil domain containing 107 | Unconventional myosin-X; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. MYO10 binds to actin filaments and actin bundles and functions as plus end-directed motor. The tail domain binds to membranous compartments containing phosphatidylinositol 3,4,5-trisphosphate or integrins, and mediates cargo transport along actin filaments. Regulates cell shape, cell spreading and cell adhesion. Stimulates the formation and elongation of filopodia. May play a role in neurite outgrowth and axon guidance. In hippocampal neurons i [...] | 0.488 |
| CCDC107 | PAQR8 | ENSP00000414964 | ENSP00000406197 | Coiled-coil domain containing 107 | Membrane progestin receptor beta; Plasma membrane progesterone (P4) receptor coupled to G proteins. Seems to act through a G(i) mediated pathway. May be involved in oocyte maturation (By similarity). Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone; Belongs to the ADIPOR family | 0.511 |
| CCDC107 | QSOX1 | ENSP00000414964 | ENSP00000356574 | Coiled-coil domain containing 107 | Sulfhydryl oxidase 1; Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins. In fibroblasts, it may have tumor- suppressing capabilities being involved in growth regulation; Belongs to the quiescin-sulfhydryl oxidase (QSOX) family | 0.453 |
| CCDC107 | SLC37A4 | ENSP00000414964 | ENSP00000476176 | Coiled-coil domain containing 107 | Glucose-6-phosphate exchanger SLC37A4; Inorganic phosphate and glucose-6-phosphate antiporter of the endoplasmic reticulum. Transports cytoplasmic glucose-6- phosphate into the lumen of the endoplasmic reticulum and translocates inorganic phosphate into the opposite direction. Forms with glucose-6-phosphatase the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it plays a central role in homeostatic regulation of blood glucose levels; Belongs to the major facilitator superfamily. Organophosphate-Pi antiporter (OPA) (TC 2.A.1.4) family | 0.447 |
| DHX35 | CCDC107 | ENSP00000252011 | ENSP00000414964 | Probable ATP-dependent RNA helicase DHX35; May be involved in pre-mRNA splicing; Belongs to the DEAD box helicase family. DEAH subfamily | Coiled-coil domain containing 107 | 0.591 |
| DHX35 | FAF1 | ENSP00000252011 | ENSP00000379457 | Probable ATP-dependent RNA helicase DHX35; May be involved in pre-mRNA splicing; Belongs to the DEAD box helicase family. DEAH subfamily | FAS-associated factor 1; Potentiates but cannot initiate FAS-induced apoptosis; UBX domain containing | 0.458 |
| DHX35 | MYO10 | ENSP00000252011 | ENSP00000421280 | Probable ATP-dependent RNA helicase DHX35; May be involved in pre-mRNA splicing; Belongs to the DEAD box helicase family. DEAH subfamily | Unconventional myosin-X; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. MYO10 binds to actin filaments and actin bundles and functions as plus end-directed motor. The tail domain binds to membranous compartments containing phosphatidylinositol 3,4,5-trisphosphate or integrins, and mediates cargo transport along actin filaments. Regulates cell shape, cell spreading and cell adhesion. Stimulates the formation and elongation of filopodia. May play a role in neurite outgrowth and axon guidance. In hippocampal neurons i [...] | 0.513 |
| DXO | CCDC107 | ENSP00000364498 | ENSP00000414964 | Decapping and exoribonuclease protein; Ribonuclease that specifically degrades pre-mRNAs with a defective 5’ end cap and is part of a pre-mRNA capping quality control. Has decapping, pyrophosphohydrolase and 5’-3’ exonuclease activities. Has decapping activity toward incomplete 5’ end cap mRNAs such as unmethylated 5’ end-capped RNA to release GpppN and 5’ end monophosphate RNA. The 5’ end monophosphate RNA is then degraded by the 5’-3’ exoribonuclease activity, enabling this enzyme to decap and degrade incompletely capped mRNAs. Also possesses RNA 5’-pyrophosphohydrolase activity by h [...] | Coiled-coil domain containing 107 | 0.672 |
| FAF1 | CCDC107 | ENSP00000379457 | ENSP00000414964 | FAS-associated factor 1; Potentiates but cannot initiate FAS-induced apoptosis; UBX domain containing | Coiled-coil domain containing 107 | 0.511 |
| FAF1 | DHX35 | ENSP00000379457 | ENSP00000252011 | FAS-associated factor 1; Potentiates but cannot initiate FAS-induced apoptosis; UBX domain containing | Probable ATP-dependent RNA helicase DHX35; May be involved in pre-mRNA splicing; Belongs to the DEAD box helicase family. DEAH subfamily | 0.458 |
| GARNL3 | CCDC107 | ENSP00000362485 | ENSP00000414964 | GTPase-activating Rap/Ran-GAP domain-like protein 3; GTPase activating Rap/RanGAP domain like 3 | Coiled-coil domain containing 107 | 0.524 |
| GARNL3 | LMNTD1 | ENSP00000362485 | ENSP00000407353 | GTPase-activating Rap/Ran-GAP domain-like protein 3; GTPase activating Rap/RanGAP domain like 3 | Lamin tail domain containing 1 | 0.645 |
| LMNTD1 | CCDC107 | ENSP00000407353 | ENSP00000414964 | Lamin tail domain containing 1 | Coiled-coil domain containing 107 | 0.494 |
| LMNTD1 | GARNL3 | ENSP00000407353 | ENSP00000362485 | Lamin tail domain containing 1 | GTPase-activating Rap/Ran-GAP domain-like protein 3; GTPase activating Rap/RanGAP domain like 3 | 0.645 |
