node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDR2L | FADS6 | ENSP00000336587 | ENSP00000481684 | Cerebellar degeneration related protein 2 like | Fatty acid desaturase 6; Belongs to the fatty acid desaturase type 1 family | 0.626 |
CDR2L | HID1 | ENSP00000336587 | ENSP00000413520 | Cerebellar degeneration related protein 2 like | Protein HID1; May play an important role in the development of cancers in a broad range of tissues | 0.709 |
CDR2L | OTOP2 | ENSP00000336587 | ENSP00000332528 | Cerebellar degeneration related protein 2 like | Otopetrin-2; Otopetrin 2 | 0.792 |
CDR2L | STAP2 | ENSP00000336587 | ENSP00000468927 | Cerebellar degeneration related protein 2 like | Signal transducing adaptor family member 2 | 0.577 |
CDR2L | TMEM128 | ENSP00000336587 | ENSP00000372201 | Cerebellar degeneration related protein 2 like | Transmembrane protein 128 | 0.736 |
DENND2C | HID1 | ENSP00000376955 | ENSP00000413520 | DENN domain-containing protein 2C; Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP- bound form; DENN/MADD domain containing | Protein HID1; May play an important role in the development of cancers in a broad range of tissues | 0.692 |
DYM | HID1 | ENSP00000269445 | ENSP00000413520 | Dymeclin; Necessary for correct organization of Golgi apparatus. Involved in bone development; Belongs to the dymeclin family | Protein HID1; May play an important role in the development of cancers in a broad range of tissues | 0.612 |
FADS6 | CDR2L | ENSP00000481684 | ENSP00000336587 | Fatty acid desaturase 6; Belongs to the fatty acid desaturase type 1 family | Cerebellar degeneration related protein 2 like | 0.626 |
FADS6 | HID1 | ENSP00000481684 | ENSP00000413520 | Fatty acid desaturase 6; Belongs to the fatty acid desaturase type 1 family | Protein HID1; May play an important role in the development of cancers in a broad range of tissues | 0.626 |
FADS6 | OTOP2 | ENSP00000481684 | ENSP00000332528 | Fatty acid desaturase 6; Belongs to the fatty acid desaturase type 1 family | Otopetrin-2; Otopetrin 2 | 0.626 |
FADS6 | TMEM128 | ENSP00000481684 | ENSP00000372201 | Fatty acid desaturase 6; Belongs to the fatty acid desaturase type 1 family | Transmembrane protein 128 | 0.626 |
GPD1L | HID1 | ENSP00000282541 | ENSP00000413520 | Glycerol-3-phosphate dehydrogenase 1-like protein; Plays a role in regulating cardiac sodium current; decreased enzymatic activity with resulting increased levels of glycerol 3-phosphate activating the DPD1L-dependent SCN5A phosphorylation pathway, may ultimately lead to decreased sodium current; cardiac sodium current may also be reduced due to alterations of NAD(H) balance induced by DPD1L | Protein HID1; May play an important role in the development of cancers in a broad range of tissues | 0.634 |
HID1 | CDR2L | ENSP00000413520 | ENSP00000336587 | Protein HID1; May play an important role in the development of cancers in a broad range of tissues | Cerebellar degeneration related protein 2 like | 0.709 |
HID1 | DENND2C | ENSP00000413520 | ENSP00000376955 | Protein HID1; May play an important role in the development of cancers in a broad range of tissues | DENN domain-containing protein 2C; Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP- bound form; DENN/MADD domain containing | 0.692 |
HID1 | DYM | ENSP00000413520 | ENSP00000269445 | Protein HID1; May play an important role in the development of cancers in a broad range of tissues | Dymeclin; Necessary for correct organization of Golgi apparatus. Involved in bone development; Belongs to the dymeclin family | 0.612 |
HID1 | FADS6 | ENSP00000413520 | ENSP00000481684 | Protein HID1; May play an important role in the development of cancers in a broad range of tissues | Fatty acid desaturase 6; Belongs to the fatty acid desaturase type 1 family | 0.626 |
HID1 | GPD1L | ENSP00000413520 | ENSP00000282541 | Protein HID1; May play an important role in the development of cancers in a broad range of tissues | Glycerol-3-phosphate dehydrogenase 1-like protein; Plays a role in regulating cardiac sodium current; decreased enzymatic activity with resulting increased levels of glycerol 3-phosphate activating the DPD1L-dependent SCN5A phosphorylation pathway, may ultimately lead to decreased sodium current; cardiac sodium current may also be reduced due to alterations of NAD(H) balance induced by DPD1L | 0.634 |
HID1 | OTOP2 | ENSP00000413520 | ENSP00000332528 | Protein HID1; May play an important role in the development of cancers in a broad range of tissues | Otopetrin-2; Otopetrin 2 | 0.819 |
HID1 | PTCRA | ENSP00000413520 | ENSP00000477815 | Protein HID1; May play an important role in the development of cancers in a broad range of tissues | Pre T-cell antigen receptor alpha; The pre-T-cell receptor complex (composed of PTCRA, TCRB and the CD3 complex) regulates early T-cell development | 0.716 |
HID1 | STAP2 | ENSP00000413520 | ENSP00000468927 | Protein HID1; May play an important role in the development of cancers in a broad range of tissues | Signal transducing adaptor family member 2 | 0.643 |