SLC25A48 protein (human) - STRING database

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SLC25A48

Solute carrier family 25 member 48 (157 aa)

Predicted Functional Partners:

SLC47A2

0.599

SLC25A17

0.581

SLC16A9

0.553

TNFAIP8L2

0.538

TMEM88

0.524

HSPB9

0.523

KRT25

0.516

DNAH2

0.513

KRT27

0.503

MIOX

0.501

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DNAH2	SLC25A48	ENSP00000458355	ENSP00000413049	Dynein heavy chain 2, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity); Dyneins, axonemal	Solute carrier family 25 member 48	0.513
DNAH2	TMEM88	ENSP00000458355	ENSP00000301599	Dynein heavy chain 2, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity); Dyneins, axonemal	Transmembrane protein 88; Inhibits the Wnt/beta-catenin signaling pathway. Crucial for heart development and acts downstream of GATA factors in the pre-cardiac mesoderm to specify lineage commitment of cardiomyocyte development	0.573
DNAH2	TNFAIP8L2	ENSP00000458355	ENSP00000357906	Dynein heavy chain 2, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity); Dyneins, axonemal	Tumor necrosis factor alpha-induced protein 8-like protein 2; Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits JUN/AP1 and NF-kappa-B activation. Promotes Fas-induced apoptosis (By similarity); Belongs to the TNFAIP8 family. TNFAIP8L2 subfamily	0.428
HSPB9	KRT25	ENSP00000458018	ENSP00000310573	Heat shock protein family B member 9	Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization	0.494
HSPB9	KRT27	ENSP00000458018	ENSP00000301656	Heat shock protein family B member 9	Keratin, type I cytoskeletal 27; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs)	0.488
HSPB9	SLC25A48	ENSP00000458018	ENSP00000413049	Heat shock protein family B member 9	Solute carrier family 25 member 48	0.523
KRT25	HSPB9	ENSP00000310573	ENSP00000458018	Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization	Heat shock protein family B member 9	0.494
KRT25	KRT27	ENSP00000310573	ENSP00000301656	Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization	Keratin, type I cytoskeletal 27; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs)	0.917
KRT25	SLC25A48	ENSP00000310573	ENSP00000413049	Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization	Solute carrier family 25 member 48	0.516
KRT27	HSPB9	ENSP00000301656	ENSP00000458018	Keratin, type I cytoskeletal 27; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs)	Heat shock protein family B member 9	0.488
KRT27	KRT25	ENSP00000301656	ENSP00000310573	Keratin, type I cytoskeletal 27; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs)	Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization	0.917
KRT27	SLC25A48	ENSP00000301656	ENSP00000413049	Keratin, type I cytoskeletal 27; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs)	Solute carrier family 25 member 48	0.503
MIOX	SLC25A48	ENSP00000216075	ENSP00000413049	Myo-inositol oxygenase	Solute carrier family 25 member 48	0.501
SLC16A9	SLC25A48	ENSP00000378757	ENSP00000413049	Monocarboxylate transporter 9; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane; Solute carriers	Solute carrier family 25 member 48	0.553
SLC16A9	SLC47A2	ENSP00000378757	ENSP00000326671	Monocarboxylate transporter 9; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane; Solute carriers	Multidrug and toxin extrusion protein 2; Solute transporter for tetraethylammonium (TEA), 1- methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, and ganciclovir. Responsible for the secretion of cationic drugs across the brush border membranes	0.540
SLC25A17	SLC25A48	ENSP00000390722	ENSP00000413049	Peroxisomal membrane protein PMP34; Peroxisomal transporter for multiple cofactors like coenzyme A (CoA), flavin adenine dinucleotide (FAD), flavin mononucleotide (FMN) and nucleotide adenosine monophosphate (AMP), and to a lesser extent for nicotinamide adenine dinucleotide (NAD(+)), adenosine diphosphate (ADP) and adenosine 3’,5’- diphosphate (PAP). May catalyze the transport of free CoA, FAD and NAD(+) from the cytosol into the peroxisomal matrix by a counter- exchange mechanism. Inhibited by pyridoxal 5’-phosphate and bathophenanthroline in vitro; Belongs to the mitochondrial carri [...]	Solute carrier family 25 member 48	0.581
SLC25A48	DNAH2	ENSP00000413049	ENSP00000458355	Solute carrier family 25 member 48	Dynein heavy chain 2, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity); Dyneins, axonemal	0.513
SLC25A48	HSPB9	ENSP00000413049	ENSP00000458018	Solute carrier family 25 member 48	Heat shock protein family B member 9	0.523
SLC25A48	KRT25	ENSP00000413049	ENSP00000310573	Solute carrier family 25 member 48	Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization	0.516
SLC25A48	KRT27	ENSP00000413049	ENSP00000301656	Solute carrier family 25 member 48	Keratin, type I cytoskeletal 27; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs)	0.503

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