| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARHGAP6 | C2CD2 | ENSP00000338967 | ENSP00000369853 | Rho GTPase-activating protein 6; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Could regulate the interactions of signaling molecules with the actin cytoskeleton. Promotes continuous elongation of cytoplasmic processes during cell motility and simultaneous retraction of the cell body changing the cell morphology | C2 calcium dependent domain containing 2 | 0.536 |
| ARHGAP6 | INTS2 | ENSP00000338967 | ENSP00000414237 | Rho GTPase-activating protein 6; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Could regulate the interactions of signaling molecules with the actin cytoskeleton. Promotes continuous elongation of cytoplasmic processes during cell motility and simultaneous retraction of the cell body changing the cell morphology | Integrator complex subunit 2; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3’-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex | 0.427 |
| ARHGAP6 | SLC25A51 | ENSP00000338967 | ENSP00000366945 | Rho GTPase-activating protein 6; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Could regulate the interactions of signaling molecules with the actin cytoskeleton. Promotes continuous elongation of cytoplasmic processes during cell motility and simultaneous retraction of the cell body changing the cell morphology | Solute carrier family 25 member 51 | 0.474 |
| ARHGAP6 | TRAPPC1 | ENSP00000338967 | ENSP00000302783 | Rho GTPase-activating protein 6; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Could regulate the interactions of signaling molecules with the actin cytoskeleton. Promotes continuous elongation of cytoplasmic processes during cell motility and simultaneous retraction of the cell body changing the cell morphology | Trafficking protein particle complex subunit 1; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the TRAPP small subunits family. BET5 subfamily | 0.518 |
| ARHGAP6 | ZNF805 | ENSP00000338967 | ENSP00000412999 | Rho GTPase-activating protein 6; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Could regulate the interactions of signaling molecules with the actin cytoskeleton. Promotes continuous elongation of cytoplasmic processes during cell motility and simultaneous retraction of the cell body changing the cell morphology | Zinc finger protein 805; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.562 |
| C2CD2 | ARHGAP6 | ENSP00000369853 | ENSP00000338967 | C2 calcium dependent domain containing 2 | Rho GTPase-activating protein 6; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Could regulate the interactions of signaling molecules with the actin cytoskeleton. Promotes continuous elongation of cytoplasmic processes during cell motility and simultaneous retraction of the cell body changing the cell morphology | 0.536 |
| C2CD2 | INTS2 | ENSP00000369853 | ENSP00000414237 | C2 calcium dependent domain containing 2 | Integrator complex subunit 2; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3’-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex | 0.585 |
| C2CD2 | N4BP2L2 | ENSP00000369853 | ENSP00000382328 | C2 calcium dependent domain containing 2 | NEDD4 binding protein 2 like 2 | 0.453 |
| C2CD2 | PARP11 | ENSP00000369853 | ENSP00000228820 | C2 calcium dependent domain containing 2 | Poly [ADP-ribose] polymerase 11; Plays a role in nuclear envelope stability and nuclear remodeling during spermiogenesis (By similarity). In vitro, exhibits mono(ADP-ribosyl) transferase activity; Poly(ADP-ribose) polymerases | 0.532 |
| C2CD2 | RBM47 | ENSP00000369853 | ENSP00000371212 | C2 calcium dependent domain containing 2 | RNA-binding protein 47; RNA binding motif containing; Belongs to the RRM RBM47 family | 0.515 |
| C2CD2 | SLC25A51 | ENSP00000369853 | ENSP00000366945 | C2 calcium dependent domain containing 2 | Solute carrier family 25 member 51 | 0.663 |
| C2CD2 | THEM5 | ENSP00000369853 | ENSP00000357807 | C2 calcium dependent domain containing 2 | Acyl-coenzyme A thioesterase THEM5; Has acyl-CoA thioesterase activity towards long-chain (C16 and C18) fatty acyl-CoA substrates, with a preference for linoleoyl-CoA and other unsaturated long-chain fatty acid-CoA esters. Plays an important role in mitochondrial fatty acid metabolism, and in remodeling of the mitochondrial lipid cardiolipin. Required for normal mitochondrial function | 0.535 |
| C2CD2 | TRAPPC1 | ENSP00000369853 | ENSP00000302783 | C2 calcium dependent domain containing 2 | Trafficking protein particle complex subunit 1; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the TRAPP small subunits family. BET5 subfamily | 0.679 |
| C2CD2 | ZNF805 | ENSP00000369853 | ENSP00000412999 | C2 calcium dependent domain containing 2 | Zinc finger protein 805; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.702 |
| INTS2 | ARHGAP6 | ENSP00000414237 | ENSP00000338967 | Integrator complex subunit 2; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3’-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex | Rho GTPase-activating protein 6; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Could regulate the interactions of signaling molecules with the actin cytoskeleton. Promotes continuous elongation of cytoplasmic processes during cell motility and simultaneous retraction of the cell body changing the cell morphology | 0.427 |
| INTS2 | C2CD2 | ENSP00000414237 | ENSP00000369853 | Integrator complex subunit 2; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3’-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex | C2 calcium dependent domain containing 2 | 0.585 |
| INTS2 | N4BP2L2 | ENSP00000414237 | ENSP00000382328 | Integrator complex subunit 2; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3’-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex | NEDD4 binding protein 2 like 2 | 0.423 |
| INTS2 | PARP11 | ENSP00000414237 | ENSP00000228820 | Integrator complex subunit 2; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3’-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex | Poly [ADP-ribose] polymerase 11; Plays a role in nuclear envelope stability and nuclear remodeling during spermiogenesis (By similarity). In vitro, exhibits mono(ADP-ribosyl) transferase activity; Poly(ADP-ribose) polymerases | 0.415 |
| INTS2 | RBM47 | ENSP00000414237 | ENSP00000371212 | Integrator complex subunit 2; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3’-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex | RNA-binding protein 47; RNA binding motif containing; Belongs to the RRM RBM47 family | 0.404 |
| INTS2 | SLC25A51 | ENSP00000414237 | ENSP00000366945 | Integrator complex subunit 2; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3’-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex | Solute carrier family 25 member 51 | 0.533 |
