• Version:
  • 11.0 [archived version]
STRINGSTRING
AR AR MAP7D1 MAP7D1 FAM71C FAM71C LRGUK LRGUK ZNF438 ZNF438 STPG1 STPG1 CCDC60 CCDC60 ELMOD3 ELMOD3 MFSD3 MFSD3
"ZNF438" - Zinc finger protein 438 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
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[Homology]
Score
ZNF438Zinc finger protein 438; Isoform 1 acts as a transcriptional repressor; Zinc fingers C2H2-type (828 aa)    
Predicted Functional Partners:
FAM71C
Protein FAM71C; Family with sequence similarity 71 member C (241 aa)
           
  0.530
CCDC60
Coiled-coil domain containing 60 (550 aa)
           
  0.491
LRGUK
Leucine-rich repeat and guanylate kinase domain-containing protein; Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Not essential for primary cilium biogenesis; Cilia and flagella associated (825 aa)
       
 
  0.476
STPG1
O(6)-methylguanine-induced apoptosis 2; May positively contribute to the induction of apoptosis triggered by O(6)-methylguanine (334 aa)
           
  0.472
AR
Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3 (920 aa)
       
 
  0.464
MFSD3
Major facilitator superfamily domain containing 3 (412 aa)
     
   
  0.453
ELMOD3
ELMO domain-containing protein 3; Acts as a GTPase-activating protein (GAP) for ARL2 with low specific activity; Deafness associated genes (391 aa)
           
  0.441
MAP7D1
MAP7 domain containing 1; Belongs to the MAP7 family (841 aa)
       
 
  0.419
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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