• Version:
  • 11.0 [archived version]
STRINGSTRING
OR6V1 OR6V1 OR51E2 OR51E2 GPR135 GPR135 TMEM87B TMEM87B GPRC5C GPRC5C GPR137 GPR137 GPR107 GPR107 GPR158 GPR158 TMEM181 TMEM181 TM7SF3 TM7SF3 GPR108 GPR108
"GPR137" - Integral membrane protein GPR137 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
GPR137Integral membrane protein GPR137; G protein-coupled receptor 137; Belongs to the GPR137 family (475 aa)    
Predicted Functional Partners:
GPR108
G protein-coupled receptor 108; 7TM orphan receptors (543 aa)
           
  0.662
GPR107
Protein GPR107; Involved in Golgi-to-ER retrograde transport. Functions as a host factor required for infection by Pseudomonas aeruginosa exotoxin A and Campylobacter jejuni CDT toxins; Belongs to the LU7TM family (600 aa)
           
  0.571
GPR135
Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans (494 aa)
           
  0.540
OR6V1
Olfactory receptor 6V1; Odorant receptor; Olfactory receptors, family 6 (313 aa)
           
  0.532
OR51E2
Olfactory receptor 51E2; Probable G protein-coupled receptor that is activated by the short chain fatty acids (SCFA) acetate and propionate. In response to SCFA, may positively regulate renin secretion and increase blood pressure. May also be activated by steroid hormones and regulate cell proliferation. May also function as an olfactory receptor being activated by beta-ionone; Olfactory receptors, family 51 (320 aa)
           
  0.505
GPRC5C
G-protein coupled receptor family C group 5 member C; This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways; G protein-coupled receptors, Class C orphans (486 aa)
           
  0.476
TM7SF3
Transmembrane 7 superfamily member 3; Involved in the inhibition of cytokine-induced death of pancreatic beta cells. Involved in the promotion of insulin secretion from pancreatic beta cells. Is a downstream transcriptional target of p53/TP53, and acts as a pro- survival homeostatic factor that attenuates the development of cellular stress. Maintains protein homeostasis and promotes cell survival through attenuation of endoplasmic reticulum (ER) stress and the subsequent induction of unfolded protein response (UPR) (570 aa)
           
  0.464
GPR158
Probable G-protein coupled receptor 158; Orphan receptor; G protein-coupled receptors, Class C orphans (1215 aa)
     
   
  0.454
TMEM87B
Transmembrane protein 87B; May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN); Belongs to the LU7TM family. TMEM87 subfamily (555 aa)
           
  0.453
TMEM181
Transmembrane protein 181; Mediates action of cytolethal distending toxins (CDT), which are secreted by many pathogenic bacteria. Expression level of TMEM181 is rate-limiting for intoxication (612 aa)
           
  0.453
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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