• Version:
  • 11.0 [archived version]
STRINGSTRING
UGT3A2 UGT3A2 MTMR9 MTMR9 FAM153B FAM153B MTMR8 MTMR8 C9orf171 C9orf171 FAM153A FAM153A SPINK13 SPINK13 SH3D21 SH3D21 CASC10 CASC10 ARMC12 ARMC12
"FAM153A" - Protein FAM153A in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM153AProtein FAM153A; Family with sequence similarity 153 member A; Belongs to the FAM153 family (310 aa)    
Predicted Functional Partners:
FAM153B
Protein FAM153B; Family with sequence similarity 153 member B (310 aa)
     
   
0.660
C9orf171
Cilia- and flagella-associated protein 77; Chromosome 9 open reading frame 171 (320 aa)
           
  0.557
UGT3A2
UDP-glucuronosyltransferase 3A2; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity); Belongs to the UDP-glycosyltransferase family (523 aa)
           
  0.429
MTMR9
Myotubularin-related protein 9; Probable pseudophosphatase. Contains a Gly residue instead of a conserved Cys residue in the dsPTPase catalytic loop which renders it catalytically inactive as a phosphatase (Potential); Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily (549 aa)
           
  0.429
SH3D21
SH3 domain containing 21 (645 aa)
           
  0.420
SPINK13
Serine protease inhibitor Kazal-type 13; May be a serine protease inhibitor (By similarity). Essential for sperm maturation and fertility. Inhibits sperm acrosome reaction, protecting sperm from premature reaction (By similarity); Serine peptidase inhibitors, Kazal type (94 aa)
           
  0.420
CASC10
Protein CASC10; Cancer susceptibility 10 (136 aa)
           
  0.418
ARMC12
Armadillo repeat containing 12 (367 aa)
           
  0.414
MTMR8
Myotubularin-related protein 8; Phosphatase that acts on lipids with a phosphoinositol headgroup; Myotubularins (704 aa)
           
  0.402
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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