SKIDA1 protein (human) - STRING database

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SKIDA1

SKI/DACH domain containing 1 (908 aa)

Predicted Functional Partners:

VWC2L

0.688

ARL15

0.676

ARHGAP24

0.624

C10orf113

0.560

ZNF738

0.520

PRCC

0.516

ATG2A

0.504

MLLT10

0.501

PSMD3

0.494

MED26

0.493

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGAP24	ARL15	ENSP00000378611	ENSP00000433427	Rho GTPase-activating protein 24; Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamel [...]	ADP-ribosylation factor-like protein 15; ADP ribosylation factor like GTPase 15; ARF GTPase family	0.626
ARHGAP24	SKIDA1	ENSP00000378611	ENSP00000410041	Rho GTPase-activating protein 24; Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamel [...]	SKI/DACH domain containing 1	0.624
ARHGAP24	VWC2L	ENSP00000378611	ENSP00000308976	Rho GTPase-activating protein 24; Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamel [...]	Von Willebrand factor C domain-containing protein 2-like; May play a role in neurogenesis. May play a role in bone differentiation and matrix mineralization	0.572
ARL15	ARHGAP24	ENSP00000433427	ENSP00000378611	ADP-ribosylation factor-like protein 15; ADP ribosylation factor like GTPase 15; ARF GTPase family	Rho GTPase-activating protein 24; Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamel [...]	0.626
ARL15	MLLT10	ENSP00000433427	ENSP00000307411	ADP-ribosylation factor-like protein 15; ADP ribosylation factor like GTPase 15; ARF GTPase family	Protein AF-10; Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA; PHD finger proteins	0.472
ARL15	SKIDA1	ENSP00000433427	ENSP00000410041	ADP-ribosylation factor-like protein 15; ADP ribosylation factor like GTPase 15; ARF GTPase family	SKI/DACH domain containing 1	0.676
ARL15	VWC2L	ENSP00000433427	ENSP00000308976	ADP-ribosylation factor-like protein 15; ADP ribosylation factor like GTPase 15; ARF GTPase family	Von Willebrand factor C domain-containing protein 2-like; May play a role in neurogenesis. May play a role in bone differentiation and matrix mineralization	0.610
ATG2A	SKIDA1	ENSP00000366475	ENSP00000410041	Autophagy-related protein 2 homolog A; Required for both autophagosome formation and regulation of lipid droplet morphology and dispersion; Belongs to the ATG2 family	SKI/DACH domain containing 1	0.504
C10orf113	SKIDA1	ENSP00000433646	ENSP00000410041	Putative uncharacterized protein C10orf113; Chromosome 10 open reading frame 113	SKI/DACH domain containing 1	0.560
MED26	SKIDA1	ENSP00000263390	ENSP00000410041	Mediator of RNA polymerase II transcription subunit 26; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors	SKI/DACH domain containing 1	0.493
MLLT10	ARL15	ENSP00000307411	ENSP00000433427	Protein AF-10; Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA; PHD finger proteins	ADP-ribosylation factor-like protein 15; ADP ribosylation factor like GTPase 15; ARF GTPase family	0.472
MLLT10	SKIDA1	ENSP00000307411	ENSP00000410041	Protein AF-10; Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA; PHD finger proteins	SKI/DACH domain containing 1	0.501
PRCC	SKIDA1	ENSP00000271526	ENSP00000410041	Proline-rich protein PRCC; May regulate cell cycle progression through interaction with MAD2L2; Spliceosomal Bact complex	SKI/DACH domain containing 1	0.516
PSMD3	SKIDA1	ENSP00000264639	ENSP00000410041	26S proteasome non-ATPase regulatory subunit 3; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S3 family	SKI/DACH domain containing 1	0.494
SKIDA1	ARHGAP24	ENSP00000410041	ENSP00000378611	SKI/DACH domain containing 1	Rho GTPase-activating protein 24; Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamel [...]	0.624
SKIDA1	ARL15	ENSP00000410041	ENSP00000433427	SKI/DACH domain containing 1	ADP-ribosylation factor-like protein 15; ADP ribosylation factor like GTPase 15; ARF GTPase family	0.676
SKIDA1	ATG2A	ENSP00000410041	ENSP00000366475	SKI/DACH domain containing 1	Autophagy-related protein 2 homolog A; Required for both autophagosome formation and regulation of lipid droplet morphology and dispersion; Belongs to the ATG2 family	0.504
SKIDA1	C10orf113	ENSP00000410041	ENSP00000433646	SKI/DACH domain containing 1	Putative uncharacterized protein C10orf113; Chromosome 10 open reading frame 113	0.560
SKIDA1	MED26	ENSP00000410041	ENSP00000263390	SKI/DACH domain containing 1	Mediator of RNA polymerase II transcription subunit 26; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors	0.493
SKIDA1	MLLT10	ENSP00000410041	ENSP00000307411	SKI/DACH domain containing 1	Protein AF-10; Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA; PHD finger proteins	0.501

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